[Leish-l] paleopathology and leishmaniasis

[Carlos Costa]

Hi Kelly,

Aren't you interested in animal remains to look for ancestral reservoirs?

Cheers,

Carlos.

2012/1/20 Kelly Harkins <kelly.harkins at gmail.com>

> Hello all,
>
> I'm new to the mailing list and new to the leishmanisis community. I
> am a doctoral student in bioarchaeology at Arizona State University,
> focusing on the evolutionary history of leishmaniasis, specifically in
> the New World, with modern (next-generation sequencing) and ancient
> molecular approaches, as well as archaeological approach. I am also
> interested in the differential human immune response, as it seems
> there is no absolute predictable association between species of
> Leishmania and clinical outcome? As you all know, this parasite is
> fascinating!
>
> I have located some potential cases of leishmaniasis in human remains
> that have affected the underlying bone and facial structure. But in
> paleopathology, there is no standard differential diagnosis for
> determining these cases, and without the clinical background and
> without x-rays, I cannot fully understand the
> timing/nature/pattern/variability of the potential bone destruction
> that can be associated with chronic lesions, especially of the
> mucucutaneous type (more likely to show up in archaeological remains).
> I want other archaeologists to be able to add leishmaniasis to the
> list of conditions they consider when viewing skeletons in
> prehistorically endemic areas, but in my opinion, it's not quite there
> yet...
>
> So my question to the group is whether anyone knows of potential
> resources I could access to develop a better differential diagnosis in
> skeletal remains, for example, research groups with collections of
> radiographs from patients? clinics in endemic areas that would allow
> me to visit? Any ideas are appreciated.
>
> Thank you for your time,
>
> Kelly Harkins
>
> --
> Kelly M. Harkins, PhD student
> Center for Bioarchaeological Research
> School of Human Evolution and Social Change
> Arizona State University
> Tempe, AZ, 85281
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-- 
*Carlos H. N. Costa, MD, DSc.*
*Sociedade Brasileira de Medicina Tropical *
***(Brazilian Society of Tropical Medicine)*
*President*
*
*
*Universidade Federal do Piauí*
*Instituto de Doenças Tropicais Natan Portella*
*Rua Artur de Vasconcelos 151-Sul*
*64001-450 Teresina-PI*
*Brazil*
*
Telephones: +55 86 3222-4377 (W),
+55 86 3221-3062 (W),
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*

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