<font color="#000000"><font size="4"><font face="verdana,sans-serif">Hi Kelly,</font></font></font><div><font color="#000000"><font size="4"><font face="verdana,sans-serif"><br></font></font></font></div><div><font color="#000000"><font size="4"><font face="verdana,sans-serif">Aren't you interested in animal remains to look for ancestral reservoirs?</font></font></font></div>
<div><font color="#000000"><font size="4"><font face="verdana,sans-serif"><br></font></font></font></div><div><font color="#000000"><font size="4"><font face="verdana,sans-serif">Cheers,</font></font></font></div><div><font color="#000000"><font size="4"><font face="verdana,sans-serif"><br>
</font></font></font></div><div><font color="#000000"><font size="4"><font face="verdana,sans-serif">Carlos.<br></font></font></font><br><div class="gmail_quote">2012/1/20 Kelly Harkins <span dir="ltr"><<a href="mailto:kelly.harkins@gmail.com">kelly.harkins@gmail.com</a>></span><br>
<blockquote class="gmail_quote" style="margin:0 0 0 .8ex;border-left:1px #ccc solid;padding-left:1ex">Hello all,<br>
<br>
I'm new to the mailing list and new to the leishmanisis community. I<br>
am a doctoral student in bioarchaeology at Arizona State University,<br>
focusing on the evolutionary history of leishmaniasis, specifically in<br>
the New World, with modern (next-generation sequencing) and ancient<br>
molecular approaches, as well as archaeological approach. I am also<br>
interested in the differential human immune response, as it seems<br>
there is no absolute predictable association between species of<br>
Leishmania and clinical outcome? As you all know, this parasite is<br>
fascinating!<br>
<br>
I have located some potential cases of leishmaniasis in human remains<br>
that have affected the underlying bone and facial structure. But in<br>
paleopathology, there is no standard differential diagnosis for<br>
determining these cases, and without the clinical background and<br>
without x-rays, I cannot fully understand the<br>
timing/nature/pattern/variability of the potential bone destruction<br>
that can be associated with chronic lesions, especially of the<br>
mucucutaneous type (more likely to show up in archaeological remains).<br>
I want other archaeologists to be able to add leishmaniasis to the<br>
list of conditions they consider when viewing skeletons in<br>
prehistorically endemic areas, but in my opinion, it's not quite there<br>
yet...<br>
<br>
So my question to the group is whether anyone knows of potential<br>
resources I could access to develop a better differential diagnosis in<br>
skeletal remains, for example, research groups with collections of<br>
radiographs from patients? clinics in endemic areas that would allow<br>
me to visit? Any ideas are appreciated.<br>
<br>
Thank you for your time,<br>
<br>
Kelly Harkins<br>
<font color="#888888"><br>
--<br>
Kelly M. Harkins, PhD student<br>
Center for Bioarchaeological Research<br>
School of Human Evolution and Social Change<br>
Arizona State University<br>
Tempe, AZ, 85281<br>
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</font></blockquote></div><br><br clear="all"><div><br></div>-- <br><div style="text-align:center"><span style="font-family:verdana,sans-serif"><b>Carlos H. N. Costa, MD, DSc.</b></span></div><div style="text-align:center">
<span style="font-family:verdana,sans-serif"><b>Sociedade Brasileira de Medicina Tropical </b></span></div><div style="text-align:center"><b><span style="font-family:verdana,sans-serif"></span></b><span style="font-family:verdana,sans-serif"><b>(Brazilian Society of Tropical Medicine)</b></span></div>
<div style="text-align:center"><span style="font-family:verdana,sans-serif"><b>President</b></span></div><div style="text-align:center"><span style="font-family:verdana,sans-serif"><b><br></b></span></div><div style="text-align:center">
<span style="font-family:verdana,sans-serif"><b>Universidade Federal do Piauí</b></span></div><div><div style="text-align:center"><span style="font-family:verdana,sans-serif"><b>Instituto de Doenças Tropicais Natan Portella</b></span></div>
<div style="text-align:center"><font face="verdana, sans-serif"><b>Rua Artur de Vasconcelos 151-Sul</b></font></div><div><div style="text-align:center"><span style="font-family:verdana,sans-serif"><b>64001-450 Teresina-PI</b></span></div>
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