[Leish-l] spleen

[Jacob Golenser]

Dear all

Please note that leishmaniasis is an immunopathological disease (at least partially) and splenectomy reduces the autoimmune- like capacity. This may decrease pathology.

Jacob Golenser

________________________________
From: leish-l-bounces at lineu.icb.usp.br [mailto:leish-l-bounces at lineu.icb.usp.br] On Behalf Of Dr Omar Hamarsheh
Sent: ג 27 אוגוסט 2013 11:28
To: 'Carlos Costa'; 'Leish-L'
Subject: Re: [Leish-l] spleen

Dear All,
I am not an immunologist but I have an opinion that I would like to share; splenectomy cures patients with Visceral Leishmaniasis.
large masses of Leishmania in case of visceral Leishmaniasis is  existed in reticuloendothelial system including spleen. Removal of spleen will remove huge masses of the parasite infected cells. In cases of serious splenomegaly and cytopenia, spelenectomy become a good option.

All the best,
omar

-------------------------------------
Omar Hamarsheh, MSc., PhD
Al-Quds University
Department of Biological Sciences
P.O.Box 51000
Jerusalem
PALESTINE

Tel: 00970-599197097
Fax: 00970-22796960

Email: ohamarsheh at gmail.com<mailto:ohamarsheh at gmail.com>
          mail.alquds.edu/~f3706/<http://mail.alquds.edu/~f3706/>

From: leish-l-bounces at lineu.icb.usp.br [mailto:leish-l-bounces at lineu.icb.usp.br] On Behalf Of Carlos Costa
Sent: Wednesday, August 21, 2013 3:53 PM
To: Leish-L
Subject: [Leish-l] spleen

Dear leishimmunologists,

Do you have any guess on why splenectomy cures kala-azar? Would it be the absence of spleen-derived IL-10?

All my best,

Carlos.

--
Carlos H. N. Costa, MD, DSc.
Coordenador
Laboratório de Leishmanioses - LabLeish
Universidade Federal do Piauí
Instituto de Doenças Tropicais Natan Portella
Rua Artur de Vasconcelos 151-Sul
64001-450 Teresina-PI
Brazil
Telephones: +55 86 3222-4377 (W),
+55 86 3221-3062 (W),
+55 86 3237-1075 (R).


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