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<p class="MsoNormal" dir="LTR"><font size="3" color="navy" face="Times New Roman"><span style="font-size:12.0pt;color:navy">Dear all<o:p></o:p></span></font></p>
<p class="MsoNormal" dir="LTR"><font size="3" color="navy" face="Times New Roman"><span style="font-size:12.0pt;color:navy"><o:p> </o:p></span></font></p>
<p class="MsoNormal" dir="LTR"><font size="3" color="navy" face="Times New Roman"><span style="font-size:12.0pt;color:navy">Please note that leishmaniasis is an immunopathological disease (at least partially) and splenectomy reduces the autoimmune- like capacity.
This may decrease pathology.<o:p></o:p></span></font></p>
<p class="MsoNormal" dir="LTR"><font size="3" color="navy" face="Times New Roman"><span style="font-size:12.0pt;color:navy"><o:p> </o:p></span></font></p>
<p class="MsoNormal" dir="LTR"><font size="3" color="navy" face="Times New Roman"><span style="font-size:12.0pt;color:navy">Jacob Golenser<o:p></o:p></span></font></p>
<p class="MsoNormal" dir="LTR"><font size="2" color="navy" face="Arial"><span style="font-size:10.0pt;font-family:Arial;color:navy"><o:p> </o:p></span></font></p>
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<hr size="2" width="100%" align="center" tabindex="-1">
</span></font></div>
<p class="MsoNormal" dir="LTR"><b><font size="2" face="Tahoma"><span style="font-size:
10.0pt;font-family:Tahoma;font-weight:bold">From:</span></font></b><font size="2" face="Tahoma"><span style="font-size:10.0pt;font-family:Tahoma"> leish-l-bounces@lineu.icb.usp.br
[mailto:leish-l-bounces@lineu.icb.usp.br] <b><span style="font-weight:bold">On Behalf Of
</span></b>Dr Omar Hamarsheh<br>
<b><span style="font-weight:bold">Sent:</span></b> </span></font><font size="2" face="Tahoma"><span lang="HE" dir="RTL" style="font-size:10.0pt;font-family:Tahoma">ג</span></font><span dir="LTR"></span><font size="2" face="Tahoma"><span style="font-size:10.0pt;
font-family:Tahoma"><span dir="LTR"></span>
27 </span></font><font size="2" face="Tahoma"><span lang="HE" dir="RTL" style="font-size:10.0pt;font-family:Tahoma">אוגוסט</span></font><span dir="LTR"></span><font size="2" face="Tahoma"><span style="font-size:10.0pt;
font-family:Tahoma"><span dir="LTR"></span>
2013 11:28<br>
<b><span style="font-weight:bold">To:</span></b> 'Carlos Costa'; 'Leish-L'<br>
<b><span style="font-weight:bold">Subject:</span></b> Re: [Leish-l] spleen</span></font><o:p></o:p></p>
</div>
<p class="MsoNormal" dir="LTR"><font size="3" face="Times New Roman"><span style="font-size:12.0pt"><o:p> </o:p></span></font></p>
<p class="MsoNormal" dir="LTR"><font size="2" color="#1f497d" face="Calibri"><span style="font-size:11.0pt;font-family:Calibri;color:#1F497D">Dear All,<o:p></o:p></span></font></p>
<p class="MsoNormal" dir="LTR"><font size="2" color="#1f497d" face="Calibri"><span style="font-size:11.0pt;font-family:Calibri;color:#1F497D">I am not an immunologist but I have an opinion that I would like to share; splenectomy cures patients with Visceral
Leishmaniasis. <o:p></o:p></span></font></p>
<p class="MsoNormal" dir="LTR"><font size="2" color="#1f497d" face="Calibri"><span style="font-size:11.0pt;font-family:Calibri;color:#1F497D">large masses of Leishmania in case of visceral Leishmaniasis is existed in reticuloendothelial system including spleen.
Removal of spleen will remove huge masses of the parasite infected cells. In cases of serious splenomegaly and cytopenia, spelenectomy become a good option.<o:p></o:p></span></font></p>
<p class="MsoNormal" dir="LTR"><font size="2" color="#1f497d" face="Calibri"><span style="font-size:11.0pt;font-family:Calibri;color:#1F497D"><o:p> </o:p></span></font></p>
<p class="MsoNormal" dir="LTR"><font size="2" color="#1f497d" face="Calibri"><span style="font-size:11.0pt;font-family:Calibri;color:#1F497D">All the best,<o:p></o:p></span></font></p>
<p class="MsoNormal" dir="LTR"><font size="2" color="#1f497d" face="Calibri"><span style="font-size:11.0pt;font-family:Calibri;color:#1F497D">omar<o:p></o:p></span></font></p>
<p class="MsoNormal" dir="LTR"><font size="2" color="#1f497d" face="Calibri"><span style="font-size:11.0pt;font-family:Calibri;color:#1F497D"><o:p> </o:p></span></font></p>
<p class="MsoNormal" dir="LTR"><b><font size="3" color="black" face="Times New Roman"><span style="font-size:12.0pt;color:black;font-weight:bold">-------------------------------------<o:p></o:p></span></font></b></p>
<p class="MsoNormal" dir="LTR"><b><font size="3" color="black" face="Times New Roman"><span style="font-size:12.0pt;color:black;font-weight:bold">Omar Hamarsheh, MSc., PhD<o:p></o:p></span></font></b></p>
<p class="MsoNormal" dir="LTR"><st1:place w:st="on"><st1:PlaceName w:st="on"><b><font size="3" color="black" face="Times New Roman"><span style="font-size:12.0pt;
color:black;font-weight:bold">Al-Quds</span></font></b></st1:PlaceName><b><font color="black"><span style="color:black;font-weight:bold">
<st1:PlaceType w:st="on">University</st1:PlaceType></span></font></b></st1:place><b><font color="black"><span style="color:black;font-weight:bold"><o:p></o:p></span></font></b></p>
<p class="MsoNormal" dir="LTR"><b><font size="3" color="black" face="Times New Roman"><span style="font-size:12.0pt;color:black;font-weight:bold">Department of Biological Sciences<o:p></o:p></span></font></b></p>
<p class="MsoNormal" dir="LTR"><st1:address w:st="on"><st1:Street w:st="on"><b><font size="3" color="black" face="Times New Roman"><span style="font-size:12.0pt;
color:black;font-weight:bold">P.O.Box</span></font></b></st1:Street><b><font color="black"><span style="color:black;font-weight:bold">
51000</span></font></b></st1:address><b><font color="black"><span style="color:black;font-weight:bold"><o:p></o:p></span></font></b></p>
<p class="MsoNormal" dir="LTR"><st1:City w:st="on"><st1:place w:st="on"><b><font size="3" color="black" face="Times New Roman"><span style="font-size:12.0pt;
color:black;font-weight:bold">Jerusalem</span></font></b></st1:place></st1:City><b><font color="black"><span style="color:black;font-weight:bold"><o:p></o:p></span></font></b></p>
<p class="MsoNormal" dir="LTR"><st1:City w:st="on"><st1:place w:st="on"><b><font size="3" color="black" face="Times New Roman"><span style="font-size:12.0pt;
color:black;font-weight:bold">PALESTINE</span></font></b></st1:place></st1:City><b><font color="black"><span style="color:black;font-weight:bold"><o:p></o:p></span></font></b></p>
<p class="MsoNormal" dir="LTR"><b><font size="3" color="black" face="Times New Roman"><span style="font-size:12.0pt;color:black;font-weight:bold"> <o:p></o:p></span></font></b></p>
<p class="MsoNormal" dir="LTR"><b><font size="3" color="black" face="Times New Roman"><span style="font-size:12.0pt;color:black;font-weight:bold">Tel: 00970-599197097<o:p></o:p></span></font></b></p>
<p class="MsoNormal" dir="LTR"><b><font size="3" color="black" face="Times New Roman"><span style="font-size:12.0pt;color:black;font-weight:bold">Fax: 00970-22796960<o:p></o:p></span></font></b></p>
<p class="MsoNormal" dir="LTR"><b><font size="3" color="black" face="Times New Roman"><span style="font-size:12.0pt;color:black;font-weight:bold"> <o:p></o:p></span></font></b></p>
<p class="MsoNormal" dir="LTR"><b><font size="3" color="black" face="Times New Roman"><span style="font-size:12.0pt;color:black;font-weight:bold">Email: <a href="mailto:ohamarsheh@gmail.com" target="_blank">ohamarsheh@gmail.com</a><o:p></o:p></span></font></b></p>
<p class="MsoNormal" dir="LTR"><b><font size="3" color="black" face="Times New Roman"><span style="font-size:12.0pt;color:black;font-weight:bold"> <a href="http://mail.alquds.edu/~f3706/" target="_blank">mail.alquds.edu/~f3706/</a><o:p></o:p></span></font></b></p>
<p class="MsoNormal" dir="LTR"><font size="2" color="#1f497d" face="Calibri"><span style="font-size:11.0pt;font-family:Calibri;color:#1F497D"><o:p> </o:p></span></font></p>
<div style="border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt 0cm 0cm 0cm">
<p class="MsoNormal" dir="LTR"><b><font size="2" face="Tahoma"><span style="font-size:
10.0pt;font-family:Tahoma;font-weight:bold">From:</span></font></b><font size="2" face="Tahoma"><span style="font-size:10.0pt;font-family:Tahoma"> leish-l-bounces@lineu.icb.usp.br
[mailto:leish-l-bounces@lineu.icb.usp.br] <b><span style="font-weight:bold">On Behalf Of
</span></b>Carlos Costa<br>
<b><span style="font-weight:bold">Sent:</span></b> Wednesday, August 21, 2013 3:53 PM<br>
<b><span style="font-weight:bold">To:</span></b> Leish-L<br>
<b><span style="font-weight:bold">Subject:</span></b> [Leish-l] spleen<o:p></o:p></span></font></p>
</div>
<p class="MsoNormal" dir="LTR"><font size="3" face="Times New Roman"><span style="font-size:12.0pt"><o:p> </o:p></span></font></p>
<div>
<div>
<p class="MsoNormal" dir="LTR"><font size="3" color="black" face="Verdana"><span style="font-size:12.0pt;font-family:Verdana;color:black">Dear leishimmunologists,<o:p></o:p></span></font></p>
</div>
<div>
<p class="MsoNormal" dir="LTR"><font size="3" color="black" face="Verdana"><span style="font-size:12.0pt;font-family:Verdana;color:black"><o:p> </o:p></span></font></p>
</div>
<div>
<p class="MsoNormal" dir="LTR"><font size="3" color="black" face="Verdana"><span style="font-size:12.0pt;font-family:Verdana;color:black">Do you have any guess on why splenectomy cures kala-azar? Would it be the absence of spleen-derived IL-10?<o:p></o:p></span></font></p>
</div>
<div>
<p class="MsoNormal" dir="LTR"><font size="3" color="black" face="Verdana"><span style="font-size:12.0pt;font-family:Verdana;color:black"><o:p> </o:p></span></font></p>
</div>
<div>
<p class="MsoNormal" dir="LTR"><font size="3" color="black" face="Verdana"><span style="font-size:12.0pt;font-family:Verdana;color:black">All my best,<o:p></o:p></span></font></p>
</div>
<div>
<p class="MsoNormal" dir="LTR"><font size="3" color="black" face="Verdana"><span style="font-size:12.0pt;font-family:Verdana;color:black"><o:p> </o:p></span></font></p>
</div>
<div>
<p class="MsoNormal" dir="LTR"><font size="3" color="black" face="Verdana"><span style="font-size:12.0pt;font-family:Verdana;color:black">Carlos.<o:p></o:p></span></font></p>
</div>
<div>
<p class="MsoNormal" dir="LTR"><font size="3" face="Times New Roman"><span style="font-size:12.0pt"><o:p> </o:p></span></font></p>
</div>
<p class="MsoNormal" dir="LTR"><font size="3" face="Times New Roman"><span style="font-size:12.0pt">--
<o:p></o:p></span></font></p>
<div>
<p class="MsoNormal" dir="LTR"><font size="3" face="Verdana"><span style="font-size:
12.0pt;font-family:Verdana">Carlos H. N. Costa, MD, DSc.</span></font><o:p></o:p></p>
<p class="MsoNormal" dir="LTR"><font size="3" face="Verdana"><span style="font-size:
12.0pt;font-family:Verdana">Coordenador</span></font><o:p></o:p></p>
<p class="MsoNormal" dir="LTR"><font size="3" face="Verdana"><span style="font-size:
12.0pt;font-family:Verdana">Laboratório de Leishmanioses - LabLeish</span></font><o:p></o:p></p>
<p class="MsoNormal" dir="LTR"><font size="3" face="Verdana"><span style="font-size:
12.0pt;font-family:Verdana">Universidade Federal do Piauí</span></font><o:p></o:p></p>
<div>
<p class="MsoNormal" dir="LTR"><font size="3" face="Verdana"><span style="font-size:
12.0pt;font-family:Verdana">Instituto de Doenças Tropicais Natan Portella</span></font><o:p></o:p></p>
<p class="MsoNormal" dir="LTR"><font size="3" face="Verdana"><span style="font-size:
12.0pt;font-family:Verdana">Rua Artur de Vasconcelos 151-Sul</span></font><o:p></o:p></p>
<div>
<p class="MsoNormal" dir="LTR"><font size="3" face="Verdana"><span style="font-size:
12.0pt;font-family:Verdana">64001-450 Teresina-PI</span></font><o:p></o:p></p>
<p class="MsoNormal" dir="LTR"><st1:country-region w:st="on"><st1:place w:st="on"><font size="3" face="Verdana"><span style="font-size:12.0pt;font-family:Verdana">Brazil</span></font></st1:place></st1:country-region><font face="Verdana"><span style="font-family:Verdana"><o:p></o:p></span></font></p>
<p class="MsoNormal" dir="LTR"><font size="3" face="Verdana"><span style="font-size:
12.0pt;font-family:Verdana">Telephones: +55 86 3222-4377 (W), <o:p></o:p></span></font></p>
<p class="MsoNormal" align="center" dir="LTR" style="text-align:center"><font size="3" face="Verdana"><span style="font-size:12.0pt;font-family:Verdana">+55 86 3221-3062 (W), <o:p></o:p></span></font></p>
<p class="MsoNormal" align="center" dir="LTR" style="text-align:center"><font size="3" face="Verdana"><span style="font-size:12.0pt;font-family:Verdana">+55 86 3237-1075 (R). <o:p></o:p></span></font></p>
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12.0pt;font-family:Verdana"><o:p> </o:p></span></font></p>
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