Dear Laura Many thanks for the info. It seems that another "newish" treatment apart from allopurinol, is the aminoglycodise Aminosidine (paromomycin) - 10mg/kg b.i.d. SC for 4 weeks. Marco Romito Immunology Division Onderstepoort Veterinary Institute Private Bag X5 Onderstepoort 0110 South Africa Tel: +27-12-529-9224/8 Fax: +27-12-529-9431