[Leish-l] Mucocutaneius leishmaniasis and lipid formulations of Amphotericin B

[jlindoso at usp.br]

Dear Flavio Queiroz,
Liposomal amphotericin B has been used to treat mucosal leishmaniasis. The WHO recommend the total dose= 30 to 40 mg/kg (3 mg/kg/day). In our hospital we have been used the total dose= 30 mg/kg and we had an excelente treatment response.
Sincerely 

José Angelo Lauletta Lindoso
Laboratório de Soroepidemiologia e Imunobiologia
Instituto de Medicina Tropical de São Paulo - USP
Av. Dr. Enéas de Carvalho Aguiar, 450, Prédio II
CEP. 05403-000
Telefone:(11) 3061 - 7023
Fax: (11) 30618270


----- Flavio Queiroz Telles <queiroz.telles at uol.com.br> escreveu:
> 
> > 
> Dear Jeffrey
> 
> I am looking for some evidence about the use of the lipid formulations oaf
> Ampho B (ABELCET and AMBISOME) for the therapy of refractory or intolerant
> mucocutaneous leishmaniasis?
> Is there any published controlled clinical trial? Do you have any personal
> experience using AMBISOME or ABELCET on Mucocutaneous Leishmaniasis?
> Bets Regards
> Flavio Queiroz-Telles M
> Federal University of Parana, Brazil
> 
> 
> 
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