[Leish-l] Re : Re: inquiry

Fri Jun 17 16:28:08 BRT 2011

Dear KP
There is a fundamental point that needs to be noted  Applying heat to  
the area and using Thermomed treatment to stimulate radiowave is not  
the same.  We do not apply heat but generate heat at the molecular  
level.  I don’t think that the same effects are occurring at the  
cellular level when heat is being applied versus agitating the  
molecules to where they generate heat.  I understand that what  occurs  
at the cellular level using radio waves is being studied currently  at  
the VA Hospital in Arizona.
John

On Jun 16, 2011, at 2:35 AM, buffet pierre wrote:

> There was also a very nice poster at the last ASTMH Meeting from a  
> colleague from Tulasne in collaboration with Alejandro LLanos- 
> Cuentas using inexpensive plastic bags of sodium acetate that reach  
> temperatures close to 50°C. For an enhancing effect a few seconds of  
> contact would probably be enough.
>
> Pierre
>
> Pierre Buffet MCU-PH
> Service de Parasitologie Mycologie Pr. Mazier
> Hôpital Pitié Salpêtrière
> + 33 (0)1 42 16 01 31     + 33 (0)6 23 21 43 00
>
> Adresse postale Mailing address:
> Groupe Hospitalier Pitié-salpêtrière
> 47 Boulevard de l'hôpital
> 75651 Paris Cedex 13
> France
> Visite our webside: http://www.umrs945.upmc.fr/fr/equipe_dominique_mazier.html
>
> ----- Message d'origine -----
> De: "Chang, Kwang-Poo" <KwangPoo.Chang at rosalindfranklin.edu>
> Date: Jeudi, Juin 16, 2011 12:48 am
> Objet: Re: [Leish-l] inquiry
> À: John David <jdavid at hsph.harvard.edu>, "Magill, Alan J COL MIL USA  
> MEDCOM	WRAIR" <ALAN.MAGILL at US.ARMY.MIL>
> Cc: "Satoskar, Abhay" <Abhay.Satoskar at osumc.edu>, vishwamohan_katoch at yahoo.co.in 
> , Raj <raj at cellabs.com.au>, leish-l at lineu.icb.usp.br
>
>
>> I put my index finger into a 50 C water bath and can only stand the  
>> heat
>> for ~15 seconds.
>>
>> I wonder if someone might have tried air-activated heat pads/wraps,
>> which are inexpensive and readily available in Walgreen/CVS drug  
>> stores
>> for treating muscle pains. The temperature probably doesn't go much
>> above 40 C, but it lasts for hours and can be repeatedly applied. I  
>> used
>> such items without experiencing any problem.
>>
>> KP
>>
>> -----Original Message-----
>> From: John David [mailto:jdavid at hsph.harvard.edu]
>> Sent: Wednesday, June 08, 2011 5:34 PM
>> To: Magill, Alan J COL MIL USA MEDCOM WRAIR
>> Cc: Chang, Kwang-Poo; Satoskar, Abhay;  
>> vishwamohan_katoch at yahoo.co.in;
>> Raj; leish-l at lineu.icb.usp.br
>> Subject: Re: [Leish-l] inquiry
>>
>> Local anesthesia must be given when using heat therapy. I should
>> mention that some have advocated local lesion injection of
>> pentavalent
>> antimony. This, usually given without anesthesia, is very painful. I
>>
>> have seen it given in a clinic where adults winced terribly and it
>> was
>> complete bedlam with the loud piercing screams of  children.
>> And they had to return weekly for at least five times. I can't
>> recommend that.
>> John David
>>
>>
>>
>> On Jun 8, 2011, at 3:45 PM, Magill, Alan J COL MIL USA MEDCOM WRAIR
>>
>> wrote:
>>
>>> John certainly knows well..
>>>
>>> 50C is not tolerable to human skin. All potential lesions to be
>>> treated need to be appropriately cleaned and anesthetized with
>>> intradermal and subQ injection of lidocaine. I have never tried the
>>
>>> newer lidocaine creams such as EMLA, they might work as well. This
>>
>>> can be somewhat rate limiting for multiple lesions as each lesion
>>
>>> needs to be prepared, injected, and you need to wait about 10 plus
>>
>>> minutes for the lidocaine to work.
>>>
>>> Trying the Thermomed device on normal skin (try on yourself) will
>>
>>> show that most people can only get to about 43 or 44 C before
>>> quickly removing the device from their skin.
>>>
>>> Alan Magill
>>>
>>>
>>> ________________________________
>>> From: leish-l-bounces at lineu.icb.usp.br
>> [leish-l-bounces at lineu.icb.usp.br
>>> ] On Behalf Of Chang, Kwang-Poo  
>>> [KwangPoo.Chang at rosalindfranklin.edu]
>>> Sent: Monday, June 06, 2011 12:02 PM
>>> To: John David
>>> Cc: Satoskar, Abhay; vishwamohan_katoch at yahoo.co.in; Raj;
>> leish-l at lineu.icb.usp.br
>>> Subject: Re: [Leish-l] inquiry
>>>
>>> Any chance to make it available for additional trials elsewhere ?
>>>
>>> I recall your statement in our conversation about the advantage of
>>
>>> this instrument over the heating lamp. That is to maintain the
>>> specific elevated temperature uniformly throughout the skin lesion
>>
>>> for a sustained period. The 50 C must be the effective temperature
>>
>>> that has been experimentally determined. It seems to be a tolerable
>>
>>> temperature to human skin ?  Dr. Sharma may comment on this
>>> medically as a dermatologist ?
>>>
>>> KP
>>>
>>> ________________________________
>>> From: John David [mailto:jdavid at hsph.harvard.edu]
>>> Sent: Sunday, June 05, 2011 11:18 PM
>>> To: Chang, Kwang-Poo
>>> Cc: Sharmanl; Satoskar, Abhay; Raj; Petr Volf;
>> leish-l at lineu.icb.usp.br
>>> ; hgoto at usp.br; elfadil_abass at yahoo.com;
>> vishwamohan_katoch at yahoo.co.in
>>> Subject: Re: [Leish-l] inquiry
>>>
>>> The Themomed instrument shown below can produce accurate 50 degrees
>>
>>> C  plus or minus 0.2 degrees temperature by radio wave.
>>> from Themorsurgery Technologies. Picture below.
>>> Two papers of a trial in Brazil and one in Afghanistan on CL below.
>>
>>
>> _______________________________________________
>> Leish-l mailing list
>> Leish-l at lineu.icb.usp.br
>> http://lineu.icb.usp.br/cgi-bin/mailman/listinfo/leish-l
>>

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