[Leish-l] inquiry

[Chang, Kwang-Poo]

Dear Alan,

Most valuable information !

I read from John's article, that untreated lesions also disappeared
after thermotherapy of a single one ?

Please respond with your experience. This is an important issue.

KP

-----Original Message-----
From: Magill, Alan J COL MIL USA MEDCOM WRAIR
[mailto:ALAN.MAGILL at US.ARMY.MIL] 
Sent: Wednesday, June 08, 2011 2:45 PM
To: Chang, Kwang-Poo; John David
Cc: Satoskar, Abhay; vishwamohan_katoch at yahoo.co.in; Raj;
leish-l at lineu.icb.usp.br
Subject: RE: [Leish-l] inquiry

John certainly knows well..

50C is not tolerable to human skin. All potential lesions to be treated
need to be appropriately cleaned and anesthetized with intradermal and
subQ injection of lidocaine. I have never tried the newer lidocaine
creams such as EMLA, they might work as well. This can be somewhat rate
limiting for multiple lesions as each lesion needs to be prepared,
injected, and you need to wait about 10 plus minutes for the lidocaine
to work.

Trying the Thermomed device on normal skin (try on yourself) will show
that most people can only get to about 43 or 44 C before quickly
removing the device from their skin.

Alan Magill


________________________________
From: leish-l-bounces at lineu.icb.usp.br
[leish-l-bounces at lineu.icb.usp.br] On Behalf Of Chang, Kwang-Poo
[KwangPoo.Chang at rosalindfranklin.edu]
Sent: Monday, June 06, 2011 12:02 PM
To: John David
Cc: Satoskar, Abhay; vishwamohan_katoch at yahoo.co.in; Raj;
leish-l at lineu.icb.usp.br
Subject: Re: [Leish-l] inquiry

Any chance to make it available for additional trials elsewhere ?

I recall your statement in our conversation about the advantage of this
instrument over the heating lamp. That is to maintain the specific
elevated temperature uniformly throughout the skin lesion for a
sustained period. The 50 C must be the effective temperature that has
been experimentally determined. It seems to be a tolerable temperature
to human skin ?  Dr. Sharma may comment on this medically as a
dermatologist ?

KP

________________________________
From: John David [mailto:jdavid at hsph.harvard.edu]
Sent: Sunday, June 05, 2011 11:18 PM
To: Chang, Kwang-Poo
Cc: Sharmanl; Satoskar, Abhay; Raj; Petr Volf; leish-l at lineu.icb.usp.br;
hgoto at usp.br; elfadil_abass at yahoo.com; vishwamohan_katoch at yahoo.co.in
Subject: Re: [Leish-l] inquiry

The Themomed instrument shown below can produce accurate 50 degrees C
plus or minus 0.2 degrees temperature by radio wave.
from Themorsurgery Technologies. Picture below.
Two papers of a trial in Brazil and one in Afghanistan on CL below.