[Leish-l] inquiry

[Magill, Alan J COL MIL USA MEDCOM WRAIR]

John certainly knows well..

50C is not tolerable to human skin. All potential lesions to be treated need to be appropriately cleaned and anesthetized with intradermal and subQ injection of lidocaine. I have never tried the newer lidocaine creams such as EMLA, they might work as well. This can be somewhat rate limiting for multiple lesions as each lesion needs to be prepared, injected, and you need to wait about 10 plus minutes for the lidocaine to work.

Trying the Thermomed device on normal skin (try on yourself) will show that most people can only get to about 43 or 44 C before quickly removing the device from their skin.

Alan Magill


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From: leish-l-bounces at lineu.icb.usp.br [leish-l-bounces at lineu.icb.usp.br] On Behalf Of Chang, Kwang-Poo [KwangPoo.Chang at rosalindfranklin.edu]
Sent: Monday, June 06, 2011 12:02 PM
To: John David
Cc: Satoskar, Abhay; vishwamohan_katoch at yahoo.co.in; Raj; leish-l at lineu.icb.usp.br
Subject: Re: [Leish-l] inquiry

Any chance to make it available for additional trials elsewhere ?

I recall your statement in our conversation about the advantage of this instrument over the heating lamp. That is to maintain the specific elevated temperature uniformly throughout the skin lesion for a sustained period. The 50 C must be the effective temperature that has been experimentally determined. It seems to be a tolerable temperature to human skin ?  Dr. Sharma may comment on this medically as a dermatologist ?

KP

________________________________
From: John David [mailto:jdavid at hsph.harvard.edu]
Sent: Sunday, June 05, 2011 11:18 PM
To: Chang, Kwang-Poo
Cc: Sharmanl; Satoskar, Abhay; Raj; Petr Volf; leish-l at lineu.icb.usp.br; hgoto at usp.br; elfadil_abass at yahoo.com; vishwamohan_katoch at yahoo.co.in
Subject: Re: [Leish-l] inquiry

The Themomed instrument shown below can produce accurate 50 degrees C  plus or minus 0.2 degrees temperature by radio wave.
from Themorsurgery Technologies. Picture below.
Two papers of a trial in Brazil and one in Afghanistan on CL below.