[leish-l] Dogs and VL

[Carlos Brisola Marcondes]

Dear all,
I listened at Ribeirão Preto, São Paulo, that a phisician intended to treat
dermal leishmaniais, based in a "positive" Montenegro reaction. I saw the
arm of the patient, who lived at Mato Grosso, and the nodule was very small
(2-3 mm). The patient, a M.Sc. student, was convinced of the usefulness of
the treatment, with at least ten injections of Glucantime.
   Is the treatment really recommendable in this condition?

Sincerely yours
prof. dr. Carlos Brisola Marcondes
Depto Microb. Parasitol./CCB
UFSC- Campus Trindade
88040-900 Florianópolis (SC)

----- Original Message -----
From: Jeffrey Jon Shaw <jshaw at brturbo.com>
To: <Leish-L at bdt.org.br>
Sent: Sunday, July 21, 2002 9:06 AM
Subject: Fwd: Re: [leish-l] Dogs and VL


>
> >From: "Ellicott McConnell" <eck at intercom.net>
> >To: "Jeffrey Jon Shaw" <jshaw at brturbo.com>
> >Subject: Re: [leish-l] Dogs and VL
> >Date: Thu, 18 Jul 2002 14:17:07 -0400
> >X-Mailer: Microsoft Outlook Express 6.00.2600.0000
> >
> >Hi Jeff,
> >
> >Your message reminded me that I took a couple of technicians down to
Malakal
> >and hence up to Paloich in late 63 or early 64 and took bone marrow
samples
> >directly into hamsters from every dog (we paid per dog) in a large area
> >where VL was endemic (several hundred dogs probably)..  Not a single
"take".
> >For whatever reason the local strain does not seem to be involved with
> >canines.  Whether anyone ever tried to infect dogs with cultures from
that
> >area I don't know (or recall?).
> >
> >Something else came to mind.  I was one of the people who contracted a
> >cutaneous lesion (a view of my graying/balding head can be seen in the
> >American Journal of Trop Med & Hyg) caused by a strain identified as Ld
by
> >Adler.  About ten years later, in '74, while Harriett was in the States,
I
> >decided to go on a diet and succeeded in dropping something toward thirty
> >pounds.  At that point I became seriously ill with a high fever, had an
> >interesting spleen, etc.  I was shipped back to the Navy Hospital in the
> >States, where the haemtologists damn near bled me out, took a bone
marrow,
> >etc.  Someone claimed to have seen an Ld body in a slide, but it was
never
> >confirmed, and no one seriously proposed dong a spleen biopsy, which is
the
> >real way to diagose VL.  I was just as happy, as my spleen had not been
> >enlarged long enough to be a nice solid specimen.  Anyway, what I am
leading
> >up to is that somewhere along the way I developed an almost violent
reaction
> >to Leishmanin (not sure of that word....have not thought of it for years)
> >skin tests that left a necrotic area..  I ain't ever going to have
another
> >one; I've watched rabbits I immunized roll over and die at the prick of
the
> >needle.  BUT I wonder if anyone has thought of going into an endemic area
in
> >the Sudan, for instance, where the bug is easily found in the rodents,
and
> >in sandflies, and skin-tested the human population.  It might give a clue
as
> >to whether or not these people are, in fact, chronically infected, which
I
> >suspect may be the case, and only become patently ill when some other
> >predisposing factor is present?
> >
> >Just a thought.  Good to see your name occasionally.....Mac
> >
> >
> >----- Original Message -----
> >From: "Jeffrey Jon Shaw" <jshaw at brturbo.com>
> >To: <Leish-L at bdt.org.br>
> >Sent: Monday, July 15, 2002 6:56 PM
> >Subject: [leish-l] Dogs and VL
> >
> >
> > > An summary of the Seville meeting on canine leishmaniasis dealing with
> > > different control strategies is available in the July edition of
Trends in
> > > Parasitology:
> > > Riethinger R, Davies CR. Canine leishmaniasis: novel strategies for
> > > control. TP 18, 289-290
> > >
> > > _______________________________________________
> > > leish-l mailing list
> > > leish-l at bdt.org.br
> > > http://panda.fat.org.br/mailman/listinfo/leish-l
> > >
> > >
>
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