Fwd: Re: [leish-l] Dogs and VL

Jeffrey Jon Shaw jshaw at brturbo.com
Sun Jul 21 09:06:01 BRT 2002


>From: "Ellicott McConnell" <eck at intercom.net>
>To: "Jeffrey Jon Shaw" <jshaw at brturbo.com>
>Subject: Re: [leish-l] Dogs and VL
>Date: Thu, 18 Jul 2002 14:17:07 -0400
>X-Mailer: Microsoft Outlook Express 6.00.2600.0000
>
>Hi Jeff,
>
>Your message reminded me that I took a couple of technicians down to Malakal
>and hence up to Paloich in late 63 or early 64 and took bone marrow samples
>directly into hamsters from every dog (we paid per dog) in a large area
>where VL was endemic (several hundred dogs probably)..  Not a single "take".
>For whatever reason the local strain does not seem to be involved with
>canines.  Whether anyone ever tried to infect dogs with cultures from that
>area I don't know (or recall?).
>
>Something else came to mind.  I was one of the people who contracted a
>cutaneous lesion (a view of my graying/balding head can be seen in the
>American Journal of Trop Med & Hyg) caused by a strain identified as Ld by
>Adler.  About ten years later, in '74, while Harriett was in the States, I
>decided to go on a diet and succeeded in dropping something toward thirty
>pounds.  At that point I became seriously ill with a high fever, had an
>interesting spleen, etc.  I was shipped back to the Navy Hospital in the
>States, where the haemtologists damn near bled me out, took a bone marrow,
>etc.  Someone claimed to have seen an Ld body in a slide, but it was never
>confirmed, and no one seriously proposed dong a spleen biopsy, which is the
>real way to diagose VL.  I was just as happy, as my spleen had not been
>enlarged long enough to be a nice solid specimen.  Anyway, what I am leading
>up to is that somewhere along the way I developed an almost violent reaction
>to Leishmanin (not sure of that word....have not thought of it for years)
>skin tests that left a necrotic area..  I ain't ever going to have another
>one; I've watched rabbits I immunized roll over and die at the prick of the
>needle.  BUT I wonder if anyone has thought of going into an endemic area in
>the Sudan, for instance, where the bug is easily found in the rodents, and
>in sandflies, and skin-tested the human population.  It might give a clue as
>to whether or not these people are, in fact, chronically infected, which I
>suspect may be the case, and only become patently ill when some other
>predisposing factor is present?
>
>Just a thought.  Good to see your name occasionally.....Mac
>
>
>----- Original Message -----
>From: "Jeffrey Jon Shaw" <jshaw at brturbo.com>
>To: <Leish-L at bdt.org.br>
>Sent: Monday, July 15, 2002 6:56 PM
>Subject: [leish-l] Dogs and VL
>
>
> > An summary of the Seville meeting on canine leishmaniasis dealing with
> > different control strategies is available in the July edition of Trends in
> > Parasitology:
> > Riethinger R, Davies CR. Canine leishmaniasis: novel strategies for
> > control. TP 18, 289-290
> >
> > _______________________________________________
> > leish-l mailing list
> > leish-l at bdt.org.br
> > http://panda.fat.org.br/mailman/listinfo/leish-l
> >
> >




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