amphotericin

[Heitor Franco de Andrade Junior]

As requested, canine leishmaniasis is very difficult to treat. Most animals
dies with the infection in 6 months, despite high-dose glucantime or
association with allopurinol. Survivors presented relapses very often, more
than 80%. I had no experience with amphotericin, but I suggest that its use
will be made at higher doses, associated with Intralipid or other
commercial lipid i.v. emulsion in order to diminish toxicity.
Heitor Franco de Andrade Jr., M.D., Ph.D.
Laboratório de Protozoologia
Instituto de Medicina Tropical de São Paulo
Av.Dr.E.C.Aguiar, 470
05403-000 - São Paulo - SP
BRAZIL
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> De: Jaclamothe at aol.com
> Para: Multiple recipients of list <leish-l at bdt.org.br>
> Assunto: amphotericin
> Data: Terça-feira, 10 de Novembro de 1998 22:10
> 
> Id like to have the opinions of epidemiologist and parasitologists about
the
> treatment of dogs
> In france we begin to treat dogs with amphotericine B. Is there a risk
for
> public healh,  with resistances to this drug ( in france human leish is
often
> associated with aids)
> I think that if vet treat dogs correctly the canine reservoir will
reduce, and
> now a lot of dogs are not treated because classic treatment  expensive
and
> hard to perform ( 2 months with glucantime and 2 to 9 months allopurinol)
>  
> i hope i'll have a lot of opinions
> its important for me
> 
> merci
> jacques lamothe
> vet practicionner
> carros
> france
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