[Leish-l] Fwd: IL10 & IL-6

[Carlos Costa]

---------- Forwarded message ---------
De: Servico de Imunologia <imuno at ufba.br>
Date: qua, 7 de ago de 2019 às 08:51
Subject: Re: IL10 & IL-6
To: <chncosta at gmail.com>


Carlos,

    It is common the high production of pro-inflamatory cytokines and
anti-inflammatory cytokines as IL-10. In the majorirty of the cases IL-10
is produced in an attempt to down modulate the inflammatory response. In
the case of visceral leishmaniasis production of IL-10 is induced by
parasite antigens as well pro-inflammatory cytokines.

Edgar

----- Mensagem encaminhada -----
De: "Carlos Costa" <chncosta at gmail.com>
Para: "Leish-L" <Leish-l at lineu.icb.usp.br>
Enviadas: Sábado, 13 de julho de 2019 10:48:40
Assunto: [Leish-l] IL10 & IL-6

Hi fellows,

I am trying to understand why in human VL the anti-inflammatory IL-10 is
systemically strongly expressed together with IL-6, INF-g, and other
pro-inflammatory cytokines.

I was looking at the mechanisms behind it but found little hints. Please
let me know if you have any response for this.

Thanks a lot,

Carlos.

-- 
Carlos H. N. Costa, MD, DSc.
President
Instituto de Doenças do Sertão
*Instituto de Doenças Tropicais Natan Portella*

*Centro de Ciências da Saúde da Universidade Federal do Piauí*
*Rua Artur de Vasconcelos 151-Sul*
*64001-450 Teresina-PI*
*Brazil*
Telephones: +55 86 3222-4377 (W),
+55 86 3221-3062 (W),
+55 86 3237-1075 (H).


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-- 
Carlos H. N. Costa, MD, DSc.
President
Instituto de Doenças do Sertão
*Instituto de Doenças Tropicais Natan Portella*

*Centro de Ciências da Saúde da Universidade Federal do Piauí*
*Rua Artur de Vasconcelos 151-Sul*
*64001-450 Teresina-PI*
*Brazil*
Telephones: +55 86 3222-4377 (W),
+55 86 3221-3062 (W),
+55 86 3237-1075 (H).


Aviso: As informações contidas nesta mensagem são CONFIDENCIAIS, protegidas
pelo sigilo legal, por direitos autorais e destinadas exclusivamente à
pessoa ou organização para a qual a mensagem foi destinada.
Warning: This message is meant only for the intended recipient of the
transmission.  It is forbidden any unauthorized use, alteration,
reproduction, and distribution. If you are not the correct recipient,
please notify us immediately by return e-mail and delete this message from
your system.