[Leish-l] silent

[Carlos Costa]

Dear Paul,

Congratulations for the initiative and participation of Prevpkdl. I am
pretty sure the good products & ideas will show up.

Your last year paper (Doehl et al) was really superb and helps to
understand the "mysteries" of VL host infectiousness to sand flies. While
the very low parasitemia rules out blood as the source of parasites, the
skin role for it is still confusing when studying humans and dogs. The
surprising described patchiness of skin infectiousness seems to feel this
gap of understanding. However, somehow we should be able to identify these
sites of infectiousness in vivo. For L. donovani infection PKDL seems to
show these sites, but it is very rare in infections caused by L. infantum.
New ideas from the young researchers are welcome.

Best regards,

Carlos.


Em seg, 3 de dez de 2018 às 17:44, Paul Kaye <paul.kaye at york.ac.uk>
escreveu:

> Dear Jorge
> We have recently revived €8m from EDCTP for vaccine trial to prevent PKDL
> in Sudan
> https://www.prevpkdl.eu/about.html
>
> and others have received considerable vaccine related funding from EU/GHIT
> etc in the past couple years.
>
> So the machinery is there, but not being targeted / accessed so well in SA
>
> BW
> Paul
>
> Sent from my iPhone
>
> On 15 Nov 2018, at 19:12, Jorge Arevalo <biomoljazz at gmail.com> wrote:
>
> Dear Carlos: Perhaps we are in our quiescent stage. The scarce environment
> ($) have turned off our translation machinery. Cheers. Jorge
>
> El mié., 14 nov. 2018 a las 15:42, Carlos Costa (<chncosta at gmail.com>)
> escribió:
>
> Why leishmaniacs are so silent? Nothing to talk about? Jorge???!!!
>
> Cheers,
>
> Carlos.
>
>
> --
>
> Carlos H. N. Costa, MD, DSc.
>
> President
>
> Instituto de Doenças do Sertão
>
> *Instituto de Doenças Tropicais Natan Portella*
>
>
> *Centro de Ciências da Saúde da Universidade Federal do Piauí*
>
> *Rua Artur de Vasconcelos 151-Sul*
>
> *64001-450 Teresina-PI*
>
> *Brazil*
>
> Telephones: +55 86 3222-4377 (W),
>
> +55 86 3221-3062 (W),
>
> +55 86 3237-1075 (H).
>
>
>
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-- 
Carlos H. N. Costa, MD, DSc.
President
Instituto de Doenças do Sertão
*Instituto de Doenças Tropicais Natan Portella*

*Centro de Ciências da Saúde da Universidade Federal do Piauí*
*Rua Artur de Vasconcelos 151-Sul*
*64001-450 Teresina-PI*
*Brazil*
Telephones: +55 86 3222-4377 (W),
+55 86 3221-3062 (W),
+55 86 3237-1075 (H).


Aviso: As informações contidas nesta mensagem são CONFIDENCIAIS, protegidas
pelo sigilo legal, por direitos autorais e destinadas exclusivamente à
pessoa ou organização para a qual a mensagem foi destinada.
Warning: This message is meant only for the intended recipient of the
transmission.  It is forbidden any unauthorized use, alteration,
reproduction, and distribution. If you are not the correct recipient,
please notify us immediately by return e-mail and delete this message from
your system.