[Leish-l] [Possivel Spam] Cutaneous leishmaniasis treatment evasion

[Carlos Costa]

Dear Bartira,

I fully agree with Pierre.

Cheers,

Carlos.

Em sexta-feira, 19 de fevereiro de 2016, Pierre Buffet <pabuffet at gmail.com>
escreveu:

> Dear Bartira,
>
> please find attached 2 references on this topic that bring contrasted
> responses to your question (but "selection" criteria were different).
>
> In our experience about one third of CL patients treated with antimony and
> liposomal amphotericin B interrupt their treatment due to systemic side
> effects of variable severity. Interruption depends on the side effect but
> also on the indication. I would spend more energy and accept a higher level
> of risk to treat an immunocompromised  patient with visceral leishmaniasis
> unresponsive to amphotericin B than an immunocompetent patient with
> localized CL (most of whom should in my opinion be treated locally).
>
> Hope this is helpful.
>
> All the best
>
> Pierre
>
>
> 2016-02-18 20:35 GMT+01:00 Bartira Rossi Bergmann <bartira at biof.ufrj.br
> <javascript:_e(%7B%7D,'cvml','bartira at biof.ufrj.br');>>:
>
>> Dear colleagues,
>>
>> Does anybody have an idea of the percentage of patients that do not
>> complete the whole series of injections (overall available injectable
>> drugs) against cutaneous leishmaniasis - locally or worldwide - due to
>> adverse side effects?
>>
>> Thanks a lot!
>>
>> Bartira
>>
>>
>>
>>
>> --
>> Bartira Rossi Bergmann
>> Professora Associada
>> Instituto de Biofísica Carlos Chagas Filho
>> Universidade Federal do Rio de Janeiro - Brasil
>> tel: +55 (21) 2260-6963
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>> --
>> This email was sent by icb.usp.br
>>
>
>
>
> --
> Pr. Pierre Buffet, MD, PhD
> Faculté de Médecine Université Paris Descartes
> Institut National de la Transfusion Sanguine
> 6 rue Cabanel, 75015 Paris
> Paris, France
> Téléphone: +33 (0)6 26 16 68 11
> pabuffet at gmail.com <javascript:_e(%7B%7D,'cvml','pabuffet at gmail.com');>
>
>
>
>
> --
> * This email was sent by icb.usp.br <http://icb.usp.br> *   ­­



-- 
Carlos H. N. Costa, MD, DSc.
Coordenador
Laboratório de Leishmanioses - LabLeish
Universidade Federal do Piauí
Instituto de Doenças Tropicais Natan Portella
Rua Artur de Vasconcelos 151-Sul
64001-450 Teresina-PI
Brazil
Telephones: +55 86 3222-4377 (W),
+55 86 3221-3062 (W),
+55 86 3237-1075 (R).


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