[Leish-l] antagonists tnf-alpha and kala-azar

[josé carlos]

Dear friends,

I thought better and think etanercept or will not be useful in chronic 
infections such as leishmaniasis and even in cancers. etanercept acts on 
soluble TNF-alpha that is precisely what is elevated in autoimmune 
diseases. In cases of infections and cancer predominates transmembrane 
TNF-alpha which is the target of anti-TNF alpha monoclonal antibodies. 
So, in my humble opinion I believe that the research of leishmaniasis 
should be investigated antagonists monoclonal antibody type and 
non-receptor soluble. What do you think?

Regards,

José Carlos