[Leish-l] What are the most polemic issues in leishmaniasis?

[Isabelle Thiery]

Can you please take me off this mailing list ? thanks

Isabelle

Le 11/03/13 14:26, Cassetti, Cristina (NIH/NIAID) [E] a écrit :
>
> Can you please take me off this mailing list ?
>
> Thank you,
>
> Cristina
>
> *From:*Farrokh Modabber [mailto:fmodabber at dndi.org]
> *Sent:* Monday, February 11, 2013 7:38 PM
> *To:* 'Carlos Costa'; 'Leish-L'
> *Subject:* [Leish-l] What are the most polemic issues in leishmaniasis?
>
> Dear Carlos,
>
> I think /Leishmania/ classification should be updated.  I have problem 
> with identification of /Leishmania/ isolates based on non-biological 
> markers.  The ones used, i.e. genetic markers (not associated with 
> known biological activity), iso-enzymes electrophoresis (all the 
> isoenzymes have the same biological activity and changes somewhere in 
> the enzyme molecule cause different electrophoretic migration).  Now 
> that we know conjugation (transfer of genetic material from one to 
> another /Leishmania/) occur, and with the whole genome sequencing 
> available, isn't it time to look for biological markers?  The tools 
> used, have helped us establish the evolutionary trees but do not help 
> us in knowing what kind of disease each isolate will produce, their 
> vector specificity, etc.  I realize that disease outcome also depends 
> on host response, but still some better markers may be identified.
>
> What do you think?
>
> All the best,
>
> Farrokh
>
> *From:*leish-l-bounces at lineu.icb.usp.br 
> <mailto:leish-l-bounces at lineu.icb.usp.br> 
> [mailto:leish-l-bounces at lineu.icb.usp.br] *On Behalf Of *Israel Cruz Mata
> *Sent:* lundi 11 février 2013 09:46
> *To:* 'Carlos Costa'; 'Leish-L'
> *Subject:* Re: [Leish-l] hot spots
>
> Hi Carlos,
>
> I´m curious about these:
>
> -"Leishmania siamensis": causing dermal and visceral human 
> leishmaniasis in Thailand, cutaneous equine and bovine leishmaniasis 
> in central Europe, and equine cutaneous leishmanaisis in USA.
>
> Is it really the same parasite in all cases, it is a new Leishmania 
> specie emerging worldwide?
>
> -Leishmania in Macropods and its transmission by midges 
> (Ceratopogonidae), not sandflies.
>
> -Control strategies for ZVL in South America: alternatives for dog 
> culling.
>
> All the best,
>
> Isra
>
> *De:*leish-l-bounces at lineu.icb.usp.br 
> <mailto:leish-l-bounces at lineu.icb.usp.br> 
> [mailto:leish-l-bounces at lineu.icb.usp.br] *En nombre de *Carlos Costa
> *Enviado el:* jueves, 07 de febrero de 2013 20:39
> *Para:* Leish-L
> *Asunto:* [Leish-l] hot spots
>
> What are the most polemic issues in leishmaniasis?
>
> -- 
>
> Carlos H. N. Costa, MD, DSc.
>
> Sociedade Brasileira de Medicina Tropical
>
> (Brazilian Society of Tropical Medicine)
>
> President
>
> Universidade Federal do Piauí
>
> Instituto de Doenças Tropicais Natan Portella
>
> Rua Artur de Vasconcelos 151-Sul
>
> 64001-450 Teresina-PI
>
> Brazil
>
> Telephones: +55 86 3222-4377 (W),
>
> +55 86 3221-3062 (W),
>
> +55 86 3237-1075 (R).
>
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-- 
Isabelle Thiery, PhD
Chargée de mission pour la logistique
Batiment 7 Le Pasteur, RDC droit, pièce 16
TEl : 01 45 68 83 43
Isabelle.thiery at pasteur.fr
Institut Pasteur, 25 rue du Docteur Roux
75724 Paris Cedex 15, France



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