[Leish-l] Neurologic leish and leish association with various forms of cancer

[Joan Jackson]

Below are offered for consideration a few references relative to ongoing discussion... no claim these lists are all inclusive...re neurologic leishmanial infection/pathology; and leishmanial infections within- and with some apparent exacerbation of tumors.
 
April 2011 recent review: 
Petersen CA, West Greenlee MH, 2011. Neurologic Manifestations of Leishmania spp. Infection.  J. Neuroparasitology 1, Art. ID N110401, 5 pp. 
[contains references to neurologic leish additional to the 20 listed below.]
 
(i) Twenty (20) Peer-reviewed Science Journal Publications Reporting Leishmanial Infections of the Central Nervous System: Brain (Including the Dura Mater [tough outer membrane of brain] and Choroid Plexus [capillary blood network continuous between brain and retina or eyes], Spinal Column, and Peripheral Nerves of Humans, Monkeys, Dogs and Rodents.
 
(ii)  Three (3) Representative Peer-reviewed Science Journal Publications Reporting  40 Years or More Leishmania Infection  Asymptomatic Latency. 
 
 
(i)  Abreu-Silva AL, Calabrese KS, Tedesco RC, Mortara RA, Goncalves da Costa SC, 2003. Central nervous system involvement in experimental infection with Leishmania (Leishmania) amazonensis.  Am J Trop Med Hyg 68(6):661-665.
Avtsyn AP, Berezina EK, Kenig EE, Dursunova SM, Belova EM, Shetegelman LA, Zhukov VG, 1971.  [Experimental model of leishmaniasis meningoencephalitis.] [Article in Russian.]  Antibiotiki 16(10):885-888.
Beaver PC, Jung RC, Cupp EW, 1984.  Clinical Parasitology, ninth edition, Lea and Febiger, Philadelphia, pp. 55-77.
Carswell J, 1953.  Kala-azar at Kitui.  East African Medical Journal 30:287-293.
Garcia-Alonso M, Nieto CG, Blanco A, Requena JM, Alsonso C, Navarrete I, 1996.  Presence of antibodies in the aqueous humor and cerebrospinal fluid during Leishmania infections in dogs.  Pathologic features at the central nervous system.  Parasite Immunol 18(11):539-546. 
Hashim FA, Ahmed AE, El Hassan M, El Mubarak MH, Yagi H, Ibrahim EN, Ali MS, 1995. Neurologic changes in visceral leishmaniasis. Am J Trop Med Hyg 52(2):149-154.
Kubba R, El Hassan AM, Al-Gindan Y, Omer AH, Kutty ML, Saeed MB, 1987.  Peripheral nerve involvement in cutaneous leishmaniasis (Old World). Int J Dermatol 26(8):527-531.
Meleney HE, 1925. The histopathology of kala-azar in the hamster, monkey and man.  Am J Pathol 1:147-168.
Foglia Manzillo F, Papacone R, Cappiello S, De Santo R, Bianciardi P, Oliva G. 2009 Resolution of tongue lesions caused by Leishmania infantum in a dog treated with the association miltefosine-allopurinol. Parasit Vectors 26(2 Suppl) 1:S6.
Garin YJ, Sulahian A, Meneceur P, Pratlong F, Prina E, Gangneux J, Dedet JP, Derouin F. 2001.  Experimental pathogenicity of a presumed monoxenous trypanosomatid isolated from humans in a murine model.  J Eukaryot Microbiol 48(2):170-176.
Melo GD, Marcondes M, Vasconcelos RO, Machado GF. 2009.  Leucocyte entry into the CNS of Leishmania chagasi naturally infected dogs. Vet Parasitol 162(3-4):248-256.
Mustafa D, 1965.  Neurologic disturbances in visceral leishmaniasis. J Trop Med Hyg 68:248-250.
Nicolau S, Perard CH, 1936.  Etude histo-physio-pathologique de l’oeil et du systeme nerveux dans la leishmaniose generalisee du chien.  Ann Inst Pasteur 57(5):463-486.
Nieto CG, Vinuelas J, Blanco A, Garcia-Alonso M, Verdugo SG, Navarrete I. 1996.  Detection of Leishmania infantum amastigotes in the canine choroid plexus. Vet Rec 139(14):346-347.
Prasad LSN, Sen S, 1996.  Migration of Leishmania donovani amastigotes in the cerebrospinal fluid.  Am J Trop Med Hyg 55(6):652-654.
Satti MB, El Hassan AM, Al-Gindan Y, Osman MA, Al-Sohaibani MO, 1989.  Peripheral neural involvement in cutaneous leishmaniasis: a pathological study of human and experimental animal lesions.  Int J Dermatol 28(4):243-247.
Shortt HE, 1923.  The pathology of acute experimental kala-azar in monkeys.  Indian J Med Research 11:186-195.
Tafuri WL, Santos RL, Arantes RM, Concalves R, de Melo MN, Michalick MS, Tafuri WL. 2004. An alternative immunochemical method for detecting Leishmania amastigotes in paraffin-embedded canine tissues.  J Immunol Methods 292(1-2):17-23.
Thorson RE, Bailey WS, Hoerlein BF, Seibold HR, 1955.  A case of imported visceral leishmaniasis of a dog in the United States.  Am J Trop Med Hyg 4:18-22.
Vinuelas J, Garcia-Alonso M, Ferrando L, Navarrete I, Molano I, Miron C, Carcelen J, Alonso C, Nieto CG, 2001.  Meningeal leishmaniosis induced by Leishmania infantum in naturally infected dogs.  Vet Parasitol 101(1):23-27.
 
 
(ii)  Czechowicz RT, Millard TP, Smith HR, Ashton RE, Lucas SS, Hay RJ, 1999. Reactivation of cutaneous leishmaniasis after surgery. Br J Dermatol 141(6):1113-1116.  [“We describe an 85 year old man who developed CL on his face after recent cutaneous surgery in that site.  This case is also unusual because the most likely source of exposure to the infection occurred over 50 years previously.”]
Guilland V, Hill MP, Piens MA, Barrut D, Moullin G, 1991. [Cutaneous leishmaniasis with 48 years development.] [Article in French] Ann Dermatol Venereol 118(11):850-851.
Jewell AP, Giles FJ, 1996.  Cutaneous manifestation of leishmaniasis 40 years after exposure in a patient with chronic lymphocytic leukaemia.  Leuk Lymphoma 21(3-4):347-349.
 
Fifty-three (53) Peer-reviewed Science Journal Articles Reporting Neoplasms/Cancer: Leishmania Association
 Akcali C, Baba M, Inaloz S, Seckin D, Uzun S. 2008. Cutaneous leishmaniasis mimicking squamous cell carcinoma.  Ann Acad Med 37(5):435-436.
 
Albanese F, Poli A, Millanta F, Abramo F. 2002. Primary cutanbeous extragenital canine transmissible venereal tumor with Leishmania-laden neoplastic cells: a further suggestion of histiocytic origin?  Vet Dermatol 13(5):243-246.
 
Bialek R. 2005. [Parasitic diseases in pediatric cancer patients][Article in German] Klin Padiatr 217(Suppl 1):S85-S90.
 
Boer A, Blodorn-Schlicht N, Wiebels D, Steinkraus V, Falk TM. 2006. Unusual histopathological features of cutaneous leishmaniasis identified by polymerase chain reaction specific for Leishmania on paraffin-embedded skin biopsies.  Br J Dermatol 155(4):815-819. [Differential diagnosis includes malignant epithelial neoplasms, lymphoma…]
 
Boutros N, Hawkins D, Nelson M, Lampert IA, Naresh KN. 2006.  Burkitt lymphoma and leishmanisis in the same tissue sample in an AIDS patient.  Histopathology 48(7):880-881.
 
Brandonisio O, Fumarola L, Spinelli R, Gradoni L. 2002. Unusual presentation of leishmaniasis as an adrenal cystic mass. Eur J Clin Microbiol Infect Dis 21(9):682-683.
 
Brenner DS, Jacobs SC, Drachenberg CB, Papadimitriou JC, 2000.  Isolated visceral leishmaniasis presenting as an adrenal cyst. Arch Pathol Lab Med 124(10):1553-1556.
 
Casado JL, Cuesta C, Sanchez JA, Guerrero A, 1998. Solitary pulmonary nodule due to Leishmania in a patient with AIDS. Clin Inf Dis 26(2):532-534.
 
Casolari C, Guaraldi G, Pecorari M, Tamassia G, Cappi C, Fabio G, Cesinaro AM, Piolini R, Rumpianesi F, Presutti L. 2005. A rare case of localized mucosal leishmaniasis due to Leishmania infantum in an immunocompetent Italian host.  Eur J Epidemiol 20(6):559-561. [laryngeal tumor]
 
Castellano VM, Rodriguez-Peralto JL, Alonso S, Gomez-De la Fuente E, Ibarrola C, 1999.  Dermatofibroma parasitized by Leishmania in HIV infection: a new morphologic expression of dermal kala azar in an immunodepressed patient. J Cutan Pathol 26(10):516-519.
 
Castro Coto A, Hidalgo Hidalgo H, Solano Aguilar E, Coto Chacon F, 1987. [Leishmaniasis of the genital organs.][Article in Spanish] Med Cut Ibero Lat Am 15(2):145-150. [5 human farmers]
 
Catone G, Marino G, Poglayen G, Gramiccia M, Ludovisi A, Zanghi A.  2003. Canine transmissible venereal tumor parasitized by Leishmania infantum.  Vet Res Commun 27(7):549-553.
 
Dereure J, Duong Thanh H, Lavabre-Bertrand T, Cartron G, Bastides F, Richard-Lenoble D, Dedet JP.  2003. Visceral leishmaniasis.  Persistence of parasites in lymph nodes after clinical cure. J Infect 47(1):77-81. [drug treatment for leishmaniasis but with  lymphoma]
 
Eholie SP, Tanon AK, Folquet-Amorissani M, Doukoure B, Adoubryn KD, Yattara A, Bissagnene E. 2008. [Three new cases of visceral leishmaniasis in Cote d’Ivoire][Article in French] Bull Soc Pathol Exot 101(1):60-61.  [Note two patients had chronic lymphoid leukaemia or Burkitt lymphoma.]
 
Fakhar M, Asgari Q, Motazedian MH, Monabati A. 2008.  Mediterranean visceral leishmaniasis associated with lymphoblastic leukemia (ALL).  Parasitol Res 103(2):473-475.
 
Fiorini M, Messina MF, Barracchia A, 2002.  Peripheral intramonocytotic and intraneutrophil leishmaniasis observed in a chronic myelomonocytic leukemia (CMMoL) patient.  Haematologica 87(8):EIM21.
 
Friedman R, Hanson S, Goldberg LH, 2003. Squamous cell carcinoma arising in a Leishmania scar.  Dermatol Surg 29(11):1148-1149.
 
Gonzalez-Beato MJ, Moyano B, Sanchez C, Gonzalez-Beato MT, Perez-Molina JA, Miralles P, Lazaro P, 2000. Kaposi’s sarcoma-like lesions and other nodules as cutaneous involvement in AIDS-related visceral leishmanasis.  Br J Dermatol 143(6):1316-1318.
 
Grevot A, Jaussaud Hugues P, Marty P, Pratlong F, Ozon C, Haas P, Breton C, Bourdoiseau G, 2005.  Leishmaniosis due to Leishmania infantum in a FIV and FelV positive cat with squamous cell carcinoma diagnosed with histological, serological and isoenzymatic methods.  Parasite 12(3):271-275.
 
Kamel AH, 1945.  Lymphoblastic reticulosarcoma of the orbit.  Bull Ophthalmol Soc Egypt 38:47-49.
Hagenah GC, Wundisch T, Eckstein E, Zimmermann S, Holst F, Grimm W, Neubauer A, Lohoff M. 2007. [Sepsis-like disease in an immunocompromised patient with a travel history to Mallorca] [Article in German] Internist (Berl) 48(7):727-730. [immunoblastic B-cell lymphoma in intestine]
Kawakami A, Fukunaga T, Usui M, Asaoka H, Noda M, Nakajima T, Hashimoto Y, Tanaka A, Kishi Y, Numano F. 1996. Visceral leishmaniasis misdiagnosed as malignant lymphoma. Internal Med 35(6): 502-506.
Khatib SA, Kanj-Sharara S, Husseini ST, Nuwayri-Salti N, Semaan R, Rameh C. 2009. Leishmaniasis of the auricle mimicking carcinoma.  Am J Otolaryngol 30(4):285-287.
Kopterides P, Mourtzoukou EG, Skopelitis E, Tsavaris N, Falagas ME. 2007. Aspects of the association between leishmaniasis and malignant disorders.  Trans R Soc Trop Med Hyg 101(2):1181-1189.
Foglia Manzillo V, Pagano A, Guglielmino R, Gradoni L, Restucci B, Oliva G. 2008. Extranodal gammadelta-T-cell lymphoma in a dog with leishmaniasis. Vet Clin Pathol 37(3):298-301.
Friedman R, Hanson S, Goldberg LH. Squamous cell carcinoma arising in a Leishmania scar.  Dermatol Surg 29(11):1148-1149.
Gallego MA, Agillar A, Plaza S, Gomez JM, Burgos F, Agud JL, Marco J, Garcia C, 1996. Kaposi’s sarcoma with intense parasitization by Leishmania. Cutis 57(2):103-105.
Jewell AP, Giles FJ, 1996.  Cutaneous manifestation of leishmaniasis 40 years after exposure in a patient with chronic lymphocytic leukaemia.  Leuk Lymphoma 21(3-4):347-349.
Kawakami A, Fukunaga T, Usui M, Asaoka H, Noda M, Nakajima T, Hashimoto Y, Tanaka A, Kishi Y, Numano F, 1996. Visceral leishmaniasi misdiagnosed as malignant lymphoma.  Intern Med 35(6):502-506.
Kapila K, Prakash MB, Mehrota R, Vermar K, 1994. Testicular leishmaniasis in a boy with acute lymphoblastic leukemia.  Acta Cytol 38(5):878-879.
Marguglio A, Hoyoux C, Dresse MF, Chantraine JM, Thiry A, Gillet P, 1998. [Chronic visceral leishmaniasis during chemotherapy for metastatic osteosarcoma.][Article in French] Arch Pediatr 5(3):285-288.
Masseo A, Raim C, Foti G, Pellicano S, Foti N, 1989. [Visceral leishmaniasis as an opportunistic infection.  Our experience.] [Article in Italian] Minerva Med 80(3):303-304. [“A case of visceral leishmaniasis in a female patient suffering from acute nonlymphoid leukaemia is reported.”]
Matayoshi S, Baddina-Caramelli C, Goldbaum M, Takei LM, Honda M, Kara-Jose N, 2000.  Epidermoid carcinoma arising in an ocular leishmanial lesion.  Br J Ophthalmol  84(11):1331-1332.
Mencia-Gutierrez E, Gutierrez-Diaz E, Rodriguez-Peralto JL, Monsalve-Cordova J. 2005.  Old World eyelid cutaneous leishmaniasis: a case report.  Dermatol Online 11(3):29. [basal cell carcinoma containing leishmanial organisms.]
Mendoza H, Ardaiz MA, Sanchez-Alvarez J, Goni MA, 1997. [Leishmaniasis with hypogammaglobulinemia and its relationship with T-cell lymphoma.][Article in Spanish] Enferm Infecc Microbiol Clin 15(4):226-227.
Morsy TA, Essa TM, Ramadan NI. 2002. A woman and her son with abnormal complicated anthroponotic cutaneous leishmaniasis. J Egypt Soc Parasitol 32(3):767-774. [basal cell carcinoma: “No doubt there are progressive changes in the pathogenesis of L. tropica and that it is one of the predisposing factor of the skin cell carcinoma.”]
Morsy TA, Mangoud AM, al-Seghayer SM, 1992.  Cutaneous leishmaniasis and basal cell carcinoma in a patient from Al Baha, Saudi Arabia. J Egypt Soc Parasitol 22:167-170. 
Naik SR, Vinayak VK, Talwar P, Sehgal S, Mehra YN, Dutta BN, Chhuttani PN, 1978. Visceral leishmaniasis masquerading as a nasopharyngeal tumor. Report of a case. Trans R Soc Trop Med Hyg 72(1):43-45.
Ouaissi A, Ouaissi M. 2005.  Molecular basis of Trypanosoma cruzi and Leishmania interaction with their host(s): exploitation of immune and defense mechanisms by the parasite leading to persistence and chronicity, features reminiscent of immune system evasion strategies in cancer diseases.  Arch Immunol Ther Exp (Warsz) 53(2):102-114.
Papparella S. 2004. [Histology in diagnosis of parasitic diseases.] [Article in Italian] Parasitologia 46(1-2):157-158. [“Localization of parasites can induce hyperplastic-neoplastic lesions.  Many parasites have been associated with the occurrence of specific types of neoplasms, but the mechanisms involved are not well defined.  Chronic inflammation and/or immune suppression seem to induce neoplastic proliferation.”]
Peachy AM, Irvine GH, White H, 1994. Visceral leishmaniasis: an unusual cervical presentation.  Br J Maxillofac Surg 32(5):325-327.
Perrin C, Michiels JF, Bernard E, Hofman P, Rosenthal E, Loubiere R, 1993. Cutaneous spindle-cell pseudotumors due to Mycobacterium gordonea and Leishmania infantum. An immunophenotypic study. Am J Dermatopathol 15(6):553-558.
Perrin C, Taillin B, Hofman P, Mondain V, Lefichoux Y, Michiels JF, 1995. Atypical cutanoeus histologic features of visceral leishmaniasis in acquire immunodeficiency syndrome.  Am J Dermatopathol 17(2):145-150. [“Leishmania organism were present in the sweat ducts, suggesting transepthelial elimination through eccrine sweat glands and/or eccrine epithelial tropism.”]
Saari S, Rasi J, Anttila M, 2000.  Leishmaniosis mimicking oral neoplasm in a dog: an unusual manifestation of an unusual disease in Finland.  Acta Vet Scand 41(1):101-104.
Sabri A, Khatib L, Kanj-Sharara S, Husseini ST, Nuwayri-Salti N, Semaan R, Rameh C. 2009. Leishmaniasis of the auricle mimicking carcinoma.  Am J Otolaryngol 30(4):285-287.
Sah SP, Rijal S, Bhadani PP, Rani S, Koirala S, 2002.  Visceral leishmaniasis in two cases of leukemia.  Southeast Asian J Trop Med Public Health 33(1):25-27.
Simrnova EA, Pravatova NA, 1994. [Diagnosis of visceral leishmaniasis][Article in Russian] Arkh Patol 56(2):64-66.  [“The differential diagnosis between visceral leishmaniasis and lymphoplasmacell polmorphocell lymphosarcoma may be difficult.  One case is described in which electron microscopy allowed detection of Leishmania in the histiocytes of the spleen.”]
Suster S, Ronnen M, 1988.  Basal cell carcinoma arising in a leishmanial scar.  Int J Dermatol 27:175-176.
Toran KC, Sah SP, Joshi A, Rani S. 2003. Ulcerative post-kala azar mucosal leishmaniasis masquerading as a carcinoma-a case report. Indian J Pathol Microbiol 46(3):487-489.
Unlu RE, Altun S, Ssensoz O. 2007.  Leishmanisis scar: a risk factor for the development of basal cell carcinomas.  J Craniofac Surg 18(3):708-710.
Von Stebut E, Sunderkotter C. 2007. [Cutaneous leishmaniasis] [Article in German] Hautarzt 58(5): 445-458. [Differential diagnostic considerations include…malignant neoplasms.]
Wysluch A, Sommerer F, Ramadan H, Loeffelbein D, Wolff KD, Holzle F. 2007. [The leishmaniasis-a parasitel infection as differential diagnosis of malignant tumours of oral mucosa.  A case report and review of literature.][Article in German] Mund Kiefer Gesichtschir 11(3):167-173.
Yavuzer R, Akyurek N, Ozmen S, Demirtas Y, Ataoglu O, 2001. Leishmania cutis with B-cell cutaneous hyperplasia. Plast Reconstr Surg 108(7):2177-2178.
 
 

-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://lineu.icb.usp.br/pipermail/leish-l/attachments/20111029/ad41d378/attachment-0001.htm>