No subject


Thu Jul 7 11:54:55 BRT 2011


On 29 Sep 2011, at 00:36, "Chang, Kwang-Poo"
<KwangPoo.Chang at rosalindfranklin.edu> wrote:

	Of interest is the question of whether vaccination would clear
the infection of the pub, which has congenitally inherited L infantum ?=20

	=20

	KP

	=20

=09
________________________________


	From: Petersen, Christine A [V PTH] [mailto:kalicat at iastate.edu]

	Sent: Wednesday, September 28, 2011 11:23 AM
	To: Chang, Kwang-Poo; TECSA - Luiz Ristow; John David
	Cc: leish-l at lineu.icb.usp.br; Petersen, Christine A [V PTH]
	Subject: RE: [Leish-l] RES: testing vaccinated dogs for
immunopotentiation

	=20

	The reference for this article is:
<http://www.ncbi.nlm.nih.gov/pubmed/21532741>
http://www.ncbi.nlm.nih.gov/pubmed/21532741

	As it was published in a PLoS journal its free access to all.

	Based on our studies and recent ones from Brazil, I do believe
that to remove Leish from the canine reservoir, transmission from mom to
pup will need to be addressed.

	Christy Petersen

	=20

	From: Chang, Kwang-Poo
[mailto:KwangPoo.Chang at rosalindfranklin.edu]=20
	Sent: Wednesday, September 28, 2011 10:20 AM
	To: TECSA - Luiz Ristow; John David
	Cc: leish-l at lineu.icb.usp.br; Petersen, Christine A [V PTH]
	Subject: RE: [Leish-l] RES: testing vaccinated dogs for
immunopotentiation

	=20

	Christine Petersen published an article about transplacental
transmission of L infantum in the USA canine leishmaniasis. I just
wonder about the implication of this finding in considering vaccination
against the disease transmitted this way ?

	=20

	KP

	=20

=09
________________________________


	From: <mailto:leish-l-bounces at lineu.icb.usp.br>
leish-l-bounces at lineu.icb.usp.br
[mailto:leish-l-bounces at lineu.icb.usp.br]
<mailto:%5bmailto:leish-l-bounces at lineu.icb.usp.br%5d>  On Behalf Of
TECSA - Luiz Ristow
	Sent: Wednesday, September 28, 2011 9:08 AM
	To: 'John David'
	Cc: <mailto:leish-l at lineu.icb.usp.br> leish-l at lineu.icb.usp.br
	Subject: [Leish-l] RES: testing vaccinated dogs for
immunopotentiation

	=20

	Hi !

	=20

	There are these papers about

	These need a very critical reading to discuss

	This discussion with all about the matter and these papers is
very welcome! (at least for me!)

	Regards for all

	Luiz Ristow

	=20

	<image001.gif>

	=20

	De: <mailto:leish-l-bounces at lineu.icb.usp.br>
leish-l-bounces at lineu.icb.usp.br
[mailto:leish-l-bounces at lineu.icb.usp.br]
<mailto:%5bmailto:leish-l-bounces at lineu.icb.usp.br%5d>  Em nome de John
David
	Enviada em: segunda-feira, 26 de setembro de 2011 18:44
	Para: Dr GR Rajasekariah
	Cc: <mailto:leish-l at lineu.icb.usp.br> leish-l at lineu.icb.usp.br;
Carlos Gouvea; hubert mazure; <mailto:smithyman at cellabs.com.au>
smithyman at cellabs.com.au
	Assunto: Re: [Leish-l] testing vaccinated dogs for
immunopotentiation

	=20

	I think that for any vaccine developed to protect dogs against
VL, but which is also meant to prevent transmission of VL to humans, the
developers should show that after the vaccinated dog has been challenged
with Leishmania, it does not transmit Leishmania to sand flies.

	John R David, M.D.

	Richard Pearson Strong Professor Emeritus

	Department of Immunology and Infectious Diseases

	Harvard School of Public Health

	Professor of Medicine, Harvard Medical School

	300 W. 23rd Street, Apt. 13K

	New York, NY, 10011

	Tel: 212 414 8646

	Email: <mailto:jdavid at hsph.harvard.edu> jdavid at hsph.harvard.edu

	=20

	=20

	On Sep 19, 2011, at 12:04 AM, Dr GR Rajasekariah wrote:

	=20

	Hello EveryOne,
	I am responding to the topic on European VL Dog vaccine.
	It is a great challenge in devising a protective vaccine
against visceral leishmaniasis in dogs. This point equally applies the
same challenge for human situation.
	Because Th-2 response is so dominant during VL infection,
modulating Th-2 into Th-1 response is a big challenge to immunologists.
=09
	Key points lies in the presentation of appropriate antigen in
appropriate dose to stimulate the  Th-1 dependent protective immune
response.
	I understand several vaccines are in the market and real
efficacy of these vaccines will come out once introduced to field
conditions.
=09
	I just wanted to inform you that we have a suitable antibody kit
for testing the immunopotentiation in dogs following vaccination of
dogs.
	Our assay is based on the released promastigote antigens.
	It is a highly sensitive assay.
	Currently we supply reagents for  determination of total IgG
antibodies in serum.
	If any particular group is interested then we are able to
provide appropriate reagent for detection of specific IgG2 and other
isotype specific antibody detection.
	Because our antibody detection ELISA is based on the
exo-antigens such an ELISA would be of exceptional type for measuring
antibody response in vaccinated animals.
	Highly suitable for diagnosing dogs responded to vaccines.
=09
	Recently I came to know that some of  commercial kits were found
to be not useful for detecting seroconversion in dogs vaccinated with
FML vaccine (Leish-Immune) in Brazil.
	Because we use released antigens in our kit, any such problems
will overcome if they use Canine Leish IgG CELISA (Manufacturer Cellabs
Pty Ltd Brookvale NSW Australia email <mailto:sales at cellabs.com.au>
sales at cellabs.com.au).
	If any one is interested to know more about our antibody
detection ELISA based on exo-antigens please contact us.
=09
	This is for your kind information.
=09
	Dr GR Rajasekariah
	Sydney
	Australia
	<mailto:raj at cellabs.com.au> raj at cellabs.com.au
=09
=09
=09
=09
=09
=09
	----- Original Message ----- From: <
<mailto:leish-l-request at lineu.icb.usp.br>
leish-l-request at lineu.icb.usp.br>
	To: < <mailto:leish-l at lineu.icb.usp.br>
leish-l at lineu.icb.usp.br>
	Sent: Wednesday, August 10, 2011 5:18 PM
	Subject: Leish-l Digest, Vol 44, Issue 3

	Send Leish-l mailing list submissions to

		<mailto:leish-l at lineu.icb.usp.br>
leish-l at lineu.icb.usp.br

		=20

		To subscribe or unsubscribe via the World Wide Web,
visit

=09
<http://lineu.icb.usp.br/cgi-bin/mailman/listinfo/leish-l>
http://lineu.icb.usp.br/cgi-bin/mailman/listinfo/leish-l

		or, via email, send a message with subject or body
'help' to

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leish-l-request at lineu.icb.usp.br

		=20

		You can reach the person managing the list at

		<mailto:leish-l-owner at lineu.icb.usp.br>
leish-l-owner at lineu.icb.usp.br

		=20

		When replying, please edit your Subject line so it is
more specific

		than "Re: Contents of Leish-l digest..."

		=20

		=20

		Today's Topics:

		=20

		 1. European VL Dog Vaccine - CaniLeish?: (jeffrey shaw)

		 2. Re: FW: Leishmaniasis Pathology Network (Moazzem
Hossain)

		 3. Re: FW: Leishmaniasis Pathology Network (Moazzem
Hossain)

		=20

		=20

=09
----------------------------------------------------------------------

		=20

		Message: 1

		Date: Tue, 9 Aug 2011 15:18:44 +0000

		From: jeffrey shaw < <mailto:jayusp at hotmail.com>
jayusp at hotmail.com>

		Subject: [Leish-l] European VL Dog Vaccine - CaniLeish?:

		To: Leish-L < <mailto:leish-l at lineu.icb.usp.br>
leish-l at lineu.icb.usp.br>

		Message-ID: <
<mailto:COL101-W1CDD4171D44B715B795E9CB200 at phx.gbl>
COL101-W1CDD4171D44B715B795E9CB200 at phx.gbl>

		Content-Type: text/plain; charset=3D"windows-1252"

		=20

		=20

		CaniLeish?:

		  The European Commission granted a marketing
authorisation valid throughout the European Union, for CaniLeish to
Virbac S.A. on 14/03/2011.

		 This vaccine, CaniLeish?, will initially be launched in
Portugal at the end of the first half of 2011. This will be followed
rapidly by launches in other countries in the endemic area: Spain,
France, Greece and Italy (not in chronological order). This roll-out
takes account of the geographical prevalence of the disease and the time
required to build vaccine production up to full capacity. The launch in
Northern European countries from where there is a flow of summer
visitors to the endemic area will be part of a second phase.

		  The basis of this vaccine are excreted proteins plus a
saponin adjuvant purified from Quil-A. Its efficacy was determined in a
2 year open field trial.

		  The vaccine is given to dogs as three injections,
three weeks apart, under the skin. The first injection can be given from
six months of age, the second injection is given three weeks later and
the third three weeks from the second one. Afterward a single ?booster?
should be given every year to maintain protection.

		-------------- next part --------------

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		URL: <
<http://lineu.icb.usp.br/pipermail/leish-l/attachments/20110809/f2404f5e
/attachment-0001.htm>
http://lineu.icb.usp.br/pipermail/leish-l/attachments/20110809/f2404f5e/
attachment-0001.htm>

		=20

		------------------------------

		=20

		Message: 2

		Date: Wed, 10 Aug 2011 13:07:17 +0600

		From: Moazzem Hossain < <mailto:directordcbd at gmail.com>
directordcbd at gmail.com>

		Subject: Re: [Leish-l] FW: Leishmaniasis Pathology
Network

		To: jeffrey shaw < <mailto:jayusp at hotmail.com>
jayusp at hotmail.com>, "Prof. Paul Kaye"

		< <mailto:paul.kaye at york.ac.uk> paul.kaye at york.ac.uk>

		Cc: "Prof. Dr. Moazzem Hossain" <
<mailto:profdrmoazzemhossain at gmail.com> profdrmoazzemhossain at gmail.com>,

		Leish-L < <mailto:leish-l at lineu.icb.usp.br>
leish-l at lineu.icb.usp.br>

		Message-ID:

		<
<mailto:CAE-TCmS=3Di=3DWaT8cAeOXUJmot=3DKPvMQSLKar6CTfuUBK9M9tsUw at mail.gm=
ail.c
om> =
CAE-TCmS=3Di=3DWaT8cAeOXUJmot=3DKPvMQSLKar6CTfuUBK9M9tsUw at mail.gmail.com>=


		Content-Type: text/plain; charset=3Dwindows-1252

		=20

		10 Aug 2011

		=20

		Dear Professor Paul Kaye,

		=20

		Thank you for your email. Please find attached our
supportive letter

		of interest for Leishmaniasis Pathology Network.

		Looking forward for your kind response.

		=20

		Best regards.

		=20

		=20

		--=20

		*Prof. Dr. Moazzem Hossain *

		Ex - Director Disease Control

		Ministry of Health & Family Welfare

		Government of  Bangladesh

		*Mailing address*:

		Founder Chairman and Project Director

		Institute of Allergy & Clinical Immunology of Bangladesh
(IACIB)

		Room 4 - 5 (2nd Floor), Green Super Market, Green Road

		Dhaka -1205, Bangladesh.

		Phone:880-2-8115646 (O )

		        880-1715038551(Mobile)

		Email: <mailto:directordcbd at gmail.com>
directordcbd at gmail.com

		=20

		=20

		=20

		=20

		=20

		=20

		=20

		=20

		On 8/9/11, jeffrey shaw < <mailto:jayusp at hotmail.com>
jayusp at hotmail.com> wrote:

			=20

			=20

			=20

			Date: Tue, 9 Aug 2011 11:58:52 +0100

			From: <mailto:paul.kaye at york.ac.uk>
paul.kaye at york.ac.uk

			=20

			Subject: Leishmaniasis Pathology Network

			=20

			=20

			=20

			=20

			=20

			=20

			=20

			=20

			=20

			   Dear all,

			   Invitation to participate in a global
pathology

			     network for

			     research and training in leishmaniasis
(LeishPathNet)

			   You may recall the Dormy House meeting in
2008

			     and some of

			     the plans we put forward?  Over

			     the past

			     couple years, I have also spoken more to a
few of you about one

			     idea that was

			     formulated at Dormy, namely of setting up a
digital pathology

			     network. I have

			     also had numerous discussions with the
major equipment

			     manufacturers to see if

			     any of them would be supportive of helping
us to develop such an

			     initiative.  There have

			     been two major

			     develoments recently.  First,

			     Carl Zeiss

			     is willing to work with us to set up an
integrated global digital

			     pathology

			     network (providing a significant financial
and technical

			     contribution) and

			     second, the Wellcome Trust is willing to
review a pre-proposal to

			     fund the

			     initiative through their new Biomedical
Resources Grant scheme

			(
<http://www.wellcome.ac.uk/Funding/Biomedical-science/Funding-schemes/St
rategic-awards-and-initiatives/wtdv031727.htm>
http://www.wellcome.ac.uk/Funding/Biomedical-science/Funding-schemes/Str
ategic-awards-and-initiatives/wtdv031727.htm)

			     .

			   I have attached an outline of the project
that

			     I had sent to

			     the Trust for their initial views, which I
think is reasonably

			     self-explanatory.

			      They appeared very

			     enthusiastic!  The main

			     question now is whether enough of

			     you are still supportive? [ I will also be
sending this email to

			     others, but please feel free to circulate ]

			=20

			=20

			   I think the

			       project will be

			       challenging, but success could have a
real impact on the way we

			       conduct

			       business.  It should serve not only as a
vehicle to enhance

			       research in

			       leishmaniasis, but the model would be
equally applicable across

			       a broad range

			       of diseases and global challenges (with
leishmaniasis setting

			       the pace).

			   If we wish to

			       proceed, the requirements

			       are that we submit a pre-proposal to the
Trust by Oct 18th 2011.

			       This pre-proposal is short (4 sections of
350 words) and

			       requires

			       letters of support from the community.

			   If you are

			       supportive of the idea that

			       we try to take this forward (and there is
plenty of scope for

			       later iteration

			       of the detail), I would be grateful if
you could please provide

			       me with a

			       letter of support by September

			         12th

			         2011, indicating whether you would like
to be a network

			       partner if the bid

			       is successful.  You could

			       also be

			       supportive but not wish to become
directly involved at this

			       stage, and such

			       letters are equally valuable. Your letter
might also stress the

			       added value

			       that the network could provide, its
importance for research and

			       training and/or

			       for progressing the translational agenda.

			       It would also be an opportunity to
indicate whether your

			       group (or

			       institute, if multiple groups) would be
interested in bidding to

			       be one of the

			       initial ?designated laboratories?.

			   If there is

			       sufficient support to

			       proceed and if subsequently the
pre-proposal is successful (we

			       will know on 22nd

			       Nov), then I will need a few volunteers
to help finalise the

			       full proposal,

			       which will be due on Jan 26th 2012.

			       A funding decision will be made on May
26th

			       2012.

			   Best wishes

			       and of course I am happy to

			       discuss any points further (though I will
be out of the UK from

			       Aug 10 ?Sept

			       12)

			   Paul

			=20

			=20

			=20

			=20

			=20

			=20

			=20

			   --

			Professor Paul Kaye, Ph.D., FRCPath.

			Deputy Dean (Research), Hull York Medical
School, and

			Director, Centre for Immunology and Infection

			Department of Biology and Hull York Medical
School

			University of York

			Wentworth Way

			York YO10 5YW

			United Kingdom

			=20

			Tel:  +44 (0)1904 328840

			Fax:  +44 (0)1904 328844

			Email: <mailto:paul.kaye at york.ac.uk>
paul.kaye at york.ac.uk < <mailto:paul.kaye at york.ac.uk>
mailto:paul.kaye at york.ac.uk>

			=20

			Centre Administrator and PA: Elizabeth Greensted

			Tel:  01904 328845

			Email: <mailto:liz.greensted at york.ac.uk>
liz.greensted at york.ac.uk < <mailto:liz.greensted at york.ac.uk>
mailto:liz.greensted at york.ac.uk>

			=20

			Centre Email: <mailto:cii at york.ac.uk>
cii at york.ac.uk < <mailto:cii at york.ac.uk> mailto:cii at york.ac.uk>

			=20

			Centre website: <http://www.york.ac.uk/cii>
http://www.york.ac.uk/cii

			=20

			Times Higher Education University of the Year
2010

			=20

			Email disclaimer:
<http://www.york.ac.uk/docs/disclaimer/email.htm>
http://www.york.ac.uk/docs/disclaimer/email.htm

			=20

			=20

		=20

		=20

		------------------------------

		=20

		Message: 3

		Date: Wed, 10 Aug 2011 13:06:47 +0600

		From: Moazzem Hossain < <mailto:directordcbd at gmail.com>
directordcbd at gmail.com>

		Subject: Re: [Leish-l] FW: Leishmaniasis Pathology
Network

		To: jeffrey shaw < <mailto:jayusp at hotmail.com>
jayusp at hotmail.com>, "Prof. Paul Kaye"

		< <mailto:paul.kaye at york.ac.uk> paul.kaye at york.ac.uk>

		Cc: "Prof. Dr. Moazzem Hossain" <
<mailto:profdrmoazzemhossain at gmail.com> profdrmoazzemhossain at gmail.com>,

		Leish-L < <mailto:leish-l at lineu.icb.usp.br>
leish-l at lineu.icb.usp.br>

		Message-ID:

		<
<mailto:CAE-TCmQNUkZdNE5w+Z20bjLC-=3DvvV9BCP6OLOm9f6RV-BfpXvA at mail.gmail.=
c
om> =
CAE-TCmQNUkZdNE5w+Z20bjLC-=3DvvV9BCP6OLOm9f6RV-BfpXvA at mail.gmail.com>

		Content-Type: text/plain; charset=3D"windows-1252"

		=20

		10 Aug 2011

		=20

		Dear Professor Paul Kaye,

		=20

		Thank you for your email. Please find attached our
supportive letter

		of interest for Leishmaniasis Pathology Network.

		Looking forward for your kind response.

		=20

		Best regards.

		=20

		=20

		--=20

		*Prof. Dr. Moazzem Hossain *

		Ex - Director Disease Control

		Ministry of Health & Family Welfare

		Government of  Bangladesh

		*Mailing address*:

		Founder Chairman and Project Director

		Institute of Allergy & Clinical Immunology of Bangladesh
(IACIB)

		Room 4 - 5 (2nd Floor), Green Super Market, Green Road

		Dhaka -1205, Bangladesh.

		Phone:880-2-8115646 (O )

		        880-1715038551(Mobile)

		Email: <mailto:directordcbd at gmail.com>
directordcbd at gmail.com

		=20

		=20

		=20

		=20

		=20

		=20

		=20

		=20

		On 8/9/11, jeffrey shaw < <mailto:jayusp at hotmail.com>
jayusp at hotmail.com> wrote:

			=20

			=20

			=20

			Date: Tue, 9 Aug 2011 11:58:52 +0100

			From: <mailto:paul.kaye at york.ac.uk>
paul.kaye at york.ac.uk

			=20

			Subject: Leishmaniasis Pathology Network

			=20

			=20

			=20

			=20

			=20

			=20

			=20

			=20

			=20

			   Dear all,

			   Invitation to participate in a global
pathology

			     network for

			     research and training in leishmaniasis
(LeishPathNet)

			   You may recall the Dormy House meeting in
2008

			     and some of

			     the plans we put forward?  Over

			     the past

			     couple years, I have also spoken more to a
few of you about one

			     idea that was

			     formulated at Dormy, namely of setting up a
digital pathology

			     network. I have

			     also had numerous discussions with the
major equipment

			     manufacturers to see if

			     any of them would be supportive of helping
us to develop such an

			     initiative.  There have

			     been two major

			     develoments recently.  First,

			     Carl Zeiss

			     is willing to work with us to set up an
integrated global digital

			     pathology

			     network (providing a significant financial
and technical

			     contribution) and

			     second, the Wellcome Trust is willing to
review a pre-proposal to

			     fund the

			     initiative through their new Biomedical
Resources Grant scheme

			(
<http://www.wellcome.ac.uk/Funding/Biomedical-science/Funding-schemes/St
rategic-awards-and-initiatives/wtdv031727.htm>
http://www.wellcome.ac.uk/Funding/Biomedical-science/Funding-schemes/Str
ategic-awards-and-initiatives/wtdv031727.htm)

			     .

			   I have attached an outline of the project
that

			     I had sent to

			     the Trust for their initial views, which I
think is reasonably

			     self-explanatory.

			      They appeared very

			     enthusiastic!  The main

			     question now is whether enough of

			     you are still supportive? [ I will also be
sending this email to

			     others, but please feel free to circulate ]

			=20

			=20

			   I think the

			       project will be

			       challenging, but success could have a
real impact on the way we

			       conduct

			       business.  It should serve not only as a
vehicle to enhance

			       research in

			       leishmaniasis, but the model would be
equally applicable across

			       a broad range

			       of diseases and global challenges (with
leishmaniasis setting

			       the pace).

			   If we wish to

			       proceed, the requirements

			       are that we submit a pre-proposal to the
Trust by Oct 18th 2011.

			       This pre-proposal is short (4 sections of
350 words) and

			       requires

			       letters of support from the community.

			   If you are

			       supportive of the idea that

			       we try to take this forward (and there is
plenty of scope for

			       later iteration

			       of the detail), I would be grateful if
you could please provide

			       me with a

			       letter of support by September

			         12th

			         2011, indicating whether you would like
to be a network

			       partner if the bid

			       is successful.  You could

			       also be

			       supportive but not wish to become
directly involved at this

			       stage, and such

			       letters are equally valuable. Your letter
might also stress the

			       added value

			       that the network could provide, its
importance for research and

			       training and/or

			       for progressing the translational agenda.

			       It would also be an opportunity to
indicate whether your

			       group (or

			       institute, if multiple groups) would be
interested in bidding to

			       be one of the

			       initial ?designated laboratories?.

			   If there is

			       sufficient support to

			       proceed and if subsequently the
pre-proposal is successful (we

			       will know on 22nd

			       Nov), then I will need a few volunteers
to help finalise the

			       full proposal,

			       which will be due on Jan 26th 2012.

			       A funding decision will be made on May
26th

			       2012.

			   Best wishes

			       and of course I am happy to

			       discuss any points further (though I will
be out of the UK from

			       Aug 10 ?Sept

			       12)

			   Paul

			=20

			=20

			=20

			=20

			=20

			=20

			=20

			   --

			Professor Paul Kaye, Ph.D., FRCPath.

			Deputy Dean (Research), Hull York Medical
School, and

			Director, Centre for Immunology and Infection

			Department of Biology and Hull York Medical
School

			University of York

			Wentworth Way

			York YO10 5YW

			United Kingdom

			=20

			Tel:  +44 (0)1904 328840

			Fax:  +44 (0)1904 328844

			Email: <mailto:paul.kaye at york.ac.uk>
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<div class=3DSection1>

<p class=3DMsoNormal><font size=3D2 color=3Dnavy face=3DArial><span =
style=3D'font-size:
10.0pt;font-family:Arial;color:navy'>What Jenni said indicates that =
transplacental
transmission of canine leishmaniasis has some implication in considering =
dog vaccination.<o:p></o:p></span></font></p>

<p class=3DMsoNormal><font size=3D2 color=3Dnavy face=3DArial><span =
style=3D'font-size:
10.0pt;font-family:Arial;color:navy'><o:p>&nbsp;</o:p></span></font></p>

<p class=3DMsoNormal><font size=3D2 color=3Dnavy face=3DArial><span =
style=3D'font-size:
10.0pt;font-family:Arial;color:navy'>Of further interest is the question =
of
whether this transplacental transmission could also occur in other =
reservoir
animals or even in human leishmaniasis ? I recall the description of =
such transmission
in human cases in some very early literature, but that has been always =
considered
as unlikely or extremely rare, more as a hypothesis than reality. This =
issue
may have been addressed in more recent epidemiological studies of VL =
familial
clustering in well-established endemic sites ? Congenital transmission =
might
escape our attention, should the outcome be largely asymptomatic =
?<o:p></o:p></span></font></p>

<p class=3DMsoNormal><font size=3D2 color=3Dnavy face=3DArial><span =
style=3D'font-size:
10.0pt;font-family:Arial;color:navy'><o:p>&nbsp;</o:p></span></font></p>

<p class=3DMsoNormal><font size=3D2 color=3Dnavy face=3DArial><span =
style=3D'font-size:
10.0pt;font-family:Arial;color:navy'>KP<o:p></o:p></span></font></p>

<p class=3DMsoNormal><font size=3D2 color=3Dnavy face=3DArial><span =
style=3D'font-size:
10.0pt;font-family:Arial;color:navy'><o:p>&nbsp;</o:p></span></font></p>

<div>

<div class=3DMsoNormal align=3Dcenter style=3D'text-align:center'><font =
size=3D3
face=3D"Times New Roman"><span style=3D'font-size:12.0pt'>

<hr size=3D2 width=3D"100%" align=3Dcenter tabindex=3D-1>

</span></font></div>

<p class=3DMsoNormal><b><font size=3D2 face=3DTahoma><span =
style=3D'font-size:10.0pt;
font-family:Tahoma;font-weight:bold'>From:</span></font></b><font =
size=3D2
face=3DTahoma><span style=3D'font-size:10.0pt;font-family:Tahoma'> =
Jennie Blackwell
[mailto:jmb37 at cam.ac.uk] <br>
<b><span style=3D'font-weight:bold'>Sent:</span></b> Wednesday, October =
05, 2011
6:46 PM<br>
<b><span style=3D'font-weight:bold'>To:</span></b> Chang, Kwang-Poo<br>
<b><span style=3D'font-weight:bold'>Cc:</span></b> Petersen, Christine A =
[V PTH];
TECSA - Luiz Ristow; John David; leish-l at lineu.icb.usp.br<br>
<b><span style=3D'font-weight:bold'>Subject:</span></b> Re: [Leish-l] =
RES:
testing vaccinated dogs for =
immunopotentiation</span></font><o:p></o:p></p>

</div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
style=3D'font-size:
12.0pt'><o:p>&nbsp;</o:p></span></font></p>

<div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
style=3D'font-size:
12.0pt'>I doubt it. Treatment might but if the mum was already infected =
and
passed the parasite to the foetus I don't see how a vaccine would work =
to clear
the parasite from the foetus!<o:p></o:p></span></font></p>

</div>

<div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
style=3D'font-size:
12.0pt'><o:p>&nbsp;</o:p></span></font></p>

</div>

<div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
style=3D'font-size:
12.0pt'>Slightly different question as to whether vaccinating mums will =
give
them sufficient protection to not pass the parasite to the pup in utero =
should
they get infected themselves after =
vaccination.<o:p></o:p></span></font></p>

</div>

<div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
style=3D'font-size:
12.0pt'><o:p>&nbsp;</o:p></span></font></p>

</div>

<div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
style=3D'font-size:
12.0pt'>Cheers all, Jennie<br>
<br>
Jenefer M. Blackwell<o:p></o:p></span></font></p>

<div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
style=3D'font-size:
12.0pt'>TICHR, CCHR, UWA<o:p></o:p></span></font></p>

</div>

<div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
style=3D'font-size:
12.0pt'>Phone: +61 8 94897910<o:p></o:p></span></font></p>

</div>

<div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
style=3D'font-size:
12.0pt'>From my iPhone<o:p></o:p></span></font></p>

</div>

</div>

<div>

<p class=3DMsoNormal style=3D'margin-bottom:12.0pt'><font size=3D3
face=3D"Times New Roman"><span style=3D'font-size:12.0pt'><br>
On 29 Sep 2011, at 00:36, &quot;Chang, Kwang-Poo&quot; &lt;<a
href=3D"mailto:KwangPoo.Chang at rosalindfranklin.edu">KwangPoo.Chang at rosali=
ndfranklin.edu</a>&gt;
wrote:<o:p></o:p></span></font></p>

</div>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt' type=3Dcite>

<div><u1:smarttagtype =
namespaceuri=3D"urn:schemas-microsoft-com:office:smarttags" =
name=3D"country-region"><u1:smarttagtype =
namespaceuri=3D"urn:schemas-microsoft-com:office:smarttags" =
name=3D"place">

<p class=3DMsoNormal><font size=3D2 color=3Dnavy face=3DArial><span =
style=3D'font-size:
10.0pt;font-family:Arial;color:navy'><!--[if gte mso 9]><xml>
   <u1:shapedefaults u2:ext=3D"edit" spidmax=3D"1026"/>
</xml><![endif]--><!--[if gte mso 9]><xml>
   <u1:shapelayout u3:ext=3D"edit">
    <u1:idmap u3:ext=3D"edit" data=3D"1"/>
   </u1:shapelayout>
</xml><![endif]-->Of interest is the question of whether vaccination =
would
clear the infection of the pub, which has congenitally inherited L =
infantum ? <u1:p></u1:p></span></font><o:p></o:p></p>

<p class=3DMsoNormal><font size=3D2 color=3Dnavy face=3DArial><span =
style=3D'font-size:
10.0pt;font-family:Arial;color:navy'><u1:p>&nbsp;</u1:p></span></font><o:=
p></o:p></p>

<p class=3DMsoNormal><font size=3D2 color=3Dnavy face=3DArial><span =
style=3D'font-size:
10.0pt;font-family:Arial;color:navy'>KP<u1:p></u1:p></span></font><o:p></=
o:p></p>

<p class=3DMsoNormal><font size=3D2 color=3Dnavy face=3DArial><span =
style=3D'font-size:
10.0pt;font-family:Arial;color:navy'><u1:p>&nbsp;</u1:p></span></font><o:=
p></o:p></p>

<div>

<div class=3DMsoNormal align=3Dcenter style=3D'text-align:center'><font =
size=3D3
face=3D"Times New Roman"><span style=3D'font-size:12.0pt'>

<hr size=3D2 width=3D"100%" align=3Dcenter tabindex=3D-1>

</span></font></div>

<p class=3DMsoNormal><b><font size=3D2 face=3DTahoma><span =
style=3D'font-size:10.0pt;
font-family:Tahoma;font-weight:bold'>From:</span></font></b><font =
size=3D2
face=3DTahoma><span style=3D'font-size:10.0pt;font-family:Tahoma'> =
Petersen,
Christine A [V PTH] [mailto:kalicat at iastate.edu] <br>
<b><span style=3D'font-weight:bold'>Sent:</span></b> Wednesday, =
September 28,
2011 11:23 AM<br>
<b><span style=3D'font-weight:bold'>To:</span></b> Chang, Kwang-Poo; =
TECSA - Luiz
Ristow; John David<br>
<b><span style=3D'font-weight:bold'>Cc:</span></b> <a
href=3D"mailto:leish-l at lineu.icb.usp.br">leish-l at lineu.icb.usp.br</a>; =
Petersen,
Christine A [V PTH]<br>
<b><span style=3D'font-weight:bold'>Subject:</span></b> RE: [Leish-l] =
RES:
testing vaccinated dogs for =
immunopotentiation</span></font><u1:p></u1:p><o:p></o:p></p>

</div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
style=3D'font-size:
12.0pt'><u1:p>&nbsp;</u1:p><o:p></o:p></span></font></p>

<p class=3DMsoNormal><font size=3D2 color=3D"#1f497d" =
face=3DCalibri><span
style=3D'font-size:11.0pt;font-family:Calibri;color:#1F497D'>The =
reference for
this article is: <a =
href=3D"http://www.ncbi.nlm.nih.gov/pubmed/21532741"></a><a
href=3D"http://www.ncbi.nlm.nih.gov/pubmed/21532741">http://www.ncbi.nlm.=
nih.gov/pubmed/21532741</a><u1:p></u1:p></span></font><o:p></o:p></p>

<p class=3DMsoNormal><font size=3D2 color=3D"#1f497d" =
face=3DCalibri><span
style=3D'font-size:11.0pt;font-family:Calibri;color:#1F497D'>As it was =
published
in a PLoS journal its free access to =
all.<u1:p></u1:p></span></font><o:p></o:p></p>

<p class=3DMsoNormal><font size=3D2 color=3D"#1f497d" =
face=3DCalibri><span
style=3D'font-size:11.0pt;font-family:Calibri;color:#1F497D'>Based on =
our studies
and recent ones from <st1:country-region u4:st=3D"on"><st1:place =
u4:st=3D"on"><st1:country-region
w:st=3D"on"><st1:place =
w:st=3D"on">Brazil</st1:place></st1:country-region></st1:place></st1:coun=
try-region>,
I do believe that to remove Leish from the canine reservoir, =
transmission from
mom to pup will need to be =
addressed.<u1:p></u1:p></span></font><o:p></o:p></p>

<p class=3DMsoNormal><font size=3D2 color=3D"#1f497d" =
face=3DCalibri><span
style=3D'font-size:11.0pt;font-family:Calibri;color:#1F497D'>Christy =
Petersen<u1:p></u1:p></span></font><o:p></o:p></p>

<p class=3DMsoNormal><a name=3D"_MailEndCompose"></a><font size=3D2 =
color=3D"#1f497d"
face=3DCalibri><span =
style=3D'font-size:11.0pt;font-family:Calibri;color:#1F497D'><u1:p>&nbsp;=
</u1:p></span></font><o:p></o:p></p>

<div>

<div style=3D'border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt =
0in 0in 0in'>

<p class=3DMsoNormal><b><font size=3D2 face=3DTahoma><span =
style=3D'font-size:10.0pt;
font-family:Tahoma;font-weight:bold'>From:</span></font></b><font =
size=3D2
face=3DTahoma><span style=3D'font-size:10.0pt;font-family:Tahoma'> =
Chang, Kwang-Poo
[mailto:KwangPoo.Chang at rosalindfranklin.edu] <br>
<b><span style=3D'font-weight:bold'>Sent:</span></b> Wednesday, =
September 28,
2011 10:20 AM<br>
<b><span style=3D'font-weight:bold'>To:</span></b> TECSA - Luiz Ristow; =
John
David<br>
<b><span style=3D'font-weight:bold'>Cc:</span></b> <a
href=3D"mailto:leish-l at lineu.icb.usp.br">leish-l at lineu.icb.usp.br</a>; =
Petersen,
Christine A [V PTH]<br>
<b><span style=3D'font-weight:bold'>Subject:</span></b> RE: [Leish-l] =
RES:
testing vaccinated dogs for =
immunopotentiation<u1:p></u1:p></span></font><o:p></o:p></p>

</div>

</div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
style=3D'font-size:
12.0pt'><u1:p>&nbsp;</u1:p><o:p></o:p></span></font></p>

<p class=3DMsoNormal><font size=3D2 color=3Dnavy face=3DArial><span =
style=3D'font-size:
10.0pt;font-family:Arial;color:navy'>Christine Petersen published an =
article about
transplacental transmission of L infantum in the <st1:country-region =
u4:st=3D"on"><st1:place u4:st=3D"on"><st1:country-region
w:st=3D"on"><st1:place =
w:st=3D"on">USA</st1:place></st1:country-region></st1:place></st1:country=
-region>
canine leishmaniasis. I just wonder about the implication of this =
finding in
considering vaccination against the disease transmitted this way =
?<u1:p></u1:p></span></font><o:p></o:p></p>

<p class=3DMsoNormal><font size=3D2 color=3Dnavy face=3DArial><span =
style=3D'font-size:
10.0pt;font-family:Arial;color:navy'><u1:p>&nbsp;</u1:p></span></font><o:=
p></o:p></p>

<p class=3DMsoNormal><font size=3D2 color=3Dnavy face=3DArial><span =
style=3D'font-size:
10.0pt;font-family:Arial;color:navy'>KP<u1:p></u1:p></span></font><o:p></=
o:p></p>

<p class=3DMsoNormal><font size=3D2 color=3Dnavy face=3DArial><span =
style=3D'font-size:
10.0pt;font-family:Arial;color:navy'><u1:p>&nbsp;</u1:p></span></font><o:=
p></o:p></p>

<div>

<div class=3DMsoNormal align=3Dcenter style=3D'text-align:center'><font =
size=3D3
face=3D"Times New Roman"><span style=3D'font-size:12.0pt'>

<hr size=3D2 width=3D"100%" align=3Dcenter>

</span></font></div>

<p class=3DMsoNormal><b><font size=3D2 face=3DTahoma><span =
style=3D'font-size:10.0pt;
font-family:Tahoma;font-weight:bold'>From:</span></font></b><font =
size=3D2
face=3DTahoma><span style=3D'font-size:10.0pt;font-family:Tahoma'> <a
href=3D"mailto:leish-l-bounces at lineu.icb.usp.br"></a><a
href=3D"mailto:leish-l-bounces at lineu.icb.usp.br">leish-l-bounces at lineu.ic=
b.usp.br</a>
<a =
href=3D"mailto:%5bmailto:leish-l-bounces at lineu.icb.usp.br%5d">[mailto:lei=
sh-l-bounces at lineu.icb.usp.br]</a>
<b><span style=3D'font-weight:bold'>On Behalf Of </span></b>TECSA - Luiz =
Ristow<br>
<b><span style=3D'font-weight:bold'>Sent:</span></b> Wednesday, =
September 28,
2011 9:08 AM<br>
<b><span style=3D'font-weight:bold'>To:</span></b> 'John David'<br>
<b><span style=3D'font-weight:bold'>Cc:</span></b> <a
href=3D"mailto:leish-l at lineu.icb.usp.br"></a><a
href=3D"mailto:leish-l at lineu.icb.usp.br">leish-l at lineu.icb.usp.br</a><br>=

<b><span style=3D'font-weight:bold'>Subject:</span></b> [Leish-l] RES: =
testing
vaccinated dogs for =
immunopotentiation</span></font><u1:p></u1:p><o:p></o:p></p>

</div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
style=3D'font-size:
12.0pt'><u1:p>&nbsp;</u1:p><o:p></o:p></span></font></p>

<p class=3DMsoNormal><font size=3D2 face=3DCalibri><span lang=3DPT-BR =
style=3D'font-size:
11.0pt;font-family:Calibri'>Hi =
!<u1:p></u1:p></span></font><o:p></o:p></p>

<p class=3DMsoNormal><font size=3D2 face=3DCalibri><span lang=3DPT-BR =
style=3D'font-size:
11.0pt;font-family:Calibri'><u1:p>&nbsp;</u1:p></span></font><o:p></o:p><=
/p>

<p class=3DMsoNormal><font size=3D2 face=3DCalibri><span lang=3DPT-BR =
style=3D'font-size:
11.0pt;font-family:Calibri'>There are these papers =
about<u1:p></u1:p></span></font><o:p></o:p></p>

<p class=3DMsoNormal><font size=3D2 face=3DCalibri><span lang=3DPT-BR =
style=3D'font-size:
11.0pt;font-family:Calibri'>These need a very critical reading to =
discuss<u1:p></u1:p></span></font><o:p></o:p></p>

<p class=3DMsoNormal><font size=3D2 face=3DCalibri><span lang=3DPT-BR =
style=3D'font-size:
11.0pt;font-family:Calibri'>This discussion with all about the matter =
and these
papers is very welcome! (at least for =
me!)<u1:p></u1:p></span></font><o:p></o:p></p>

<p class=3DMsoNormal><font size=3D2 face=3DCalibri><span lang=3DPT-BR =
style=3D'font-size:
11.0pt;font-family:Calibri'>Regards for =
all<u1:p></u1:p></span></font><o:p></o:p></p>

<p class=3DMsoNormal><font size=3D2 face=3DCalibri><span lang=3DPT-BR =
style=3D'font-size:
11.0pt;font-family:Calibri'>Luiz =
Ristow<u1:p></u1:p></span></font><o:p></o:p></p>

<p class=3DMsoNormal><font size=3D2 face=3DCalibri><span lang=3DPT-BR =
style=3D'font-size:
11.0pt;font-family:Calibri'><u1:p>&nbsp;</u1:p></span></font><o:p></o:p><=
/p>

<div>

<p class=3DMsoNormal><font size=3D2 face=3DCalibri><span lang=3DPT-BR =
style=3D'font-size:
11.0pt;font-family:Calibri'>&lt;image001.gif&gt;<u1:p></u1:p></span></fon=
t><o:p></o:p></p>

</div>

<p class=3DMsoNormal><font size=3D2 face=3DCalibri><span lang=3DPT-BR =
style=3D'font-size:
11.0pt;font-family:Calibri'><u1:p>&nbsp;</u1:p></span></font><o:p></o:p><=
/p>

<div>

<div style=3D'border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt =
0in 0in 0in'>

<p class=3DMsoNormal><b><font size=3D2 face=3DTahoma><span lang=3DPT-BR
style=3D'font-size:10.0pt;font-family:Tahoma;font-weight:bold'>De:</span>=
</font></b><font
size=3D2 face=3DTahoma><span lang=3DPT-BR =
style=3D'font-size:10.0pt;font-family:Tahoma'>
<a href=3D"mailto:leish-l-bounces at lineu.icb.usp.br"></a><a
href=3D"mailto:leish-l-bounces at lineu.icb.usp.br">leish-l-bounces at lineu.ic=
b.usp.br</a>
<a =
href=3D"mailto:%5bmailto:leish-l-bounces at lineu.icb.usp.br%5d">[mailto:lei=
sh-l-bounces at lineu.icb.usp.br]</a>
<b><span style=3D'font-weight:bold'>Em nome de </span></b>John David<br>
<b><span style=3D'font-weight:bold'>Enviada em:</span></b> =
segunda-feira, 26 de
setembro de 2011 18:44<br>
<b><span style=3D'font-weight:bold'>Para:</span></b> Dr GR =
Rajasekariah<br>
<b><span style=3D'font-weight:bold'>Cc:</span></b> <a
href=3D"mailto:leish-l at lineu.icb.usp.br"></a><a
href=3D"mailto:leish-l at lineu.icb.usp.br">leish-l at lineu.icb.usp.br</a>; =
Carlos
Gouvea; hubert mazure; <a =
href=3D"mailto:smithyman at cellabs.com.au"></a><a
href=3D"mailto:smithyman at cellabs.com.au">smithyman at cellabs.com.au</a><br>=

<b><span style=3D'font-weight:bold'>Assunto:</span></b> Re: [Leish-l] =
testing
vaccinated dogs for =
immunopotentiation<u1:p></u1:p></span></font><o:p></o:p></p>

</div>

</div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

<p class=3DMsoNormal =
style=3D'mso-margin-top-alt:auto;text-autospace:none'><font
size=3D3 face=3DHelvetica><span lang=3DPT-BR =
style=3D'font-size:12.0pt;font-family:
Helvetica'>I think that for any vaccine developed to protect dogs =
against VL,
but which is also meant to prevent transmission of VL to humans, the =
developers
should show that after the vaccinated dog has been challenged with =
Leishmania,
it does not transmit Leishmania to sand =
flies.</span></font><o:p></o:p></p>

<u1:p></u1:p>

<p class=3DMsoNormal =
style=3D'mso-margin-top-alt:auto;text-autospace:none'><font
size=3D3 face=3D"Times New Roman"><span lang=3DPT-BR =
style=3D'font-size:12.0pt'>John R
David, M.D.<u1:p></u1:p></span><o:p></o:p></font></p>

<p class=3DMsoNormal =
style=3D'mso-margin-top-alt:auto;text-autospace:none'><font
size=3D3 face=3DHelvetica><span lang=3DPT-BR =
style=3D'font-size:12.0pt;font-family:
Helvetica'>Richard Pearson Strong Professor =
Emeritus</span></font><o:p></o:p></p>

<u1:p></u1:p>

<p class=3DMsoNormal =
style=3D'mso-margin-top-alt:auto;text-autospace:none'><font
size=3D3 face=3DHelvetica><span lang=3DPT-BR =
style=3D'font-size:12.0pt;font-family:
Helvetica'>Department of Immunology and Infectious =
Diseases</span></font><o:p></o:p></p>

<u1:p></u1:p>

<p class=3DMsoNormal =
style=3D'mso-margin-top-alt:auto;text-autospace:none'><font
size=3D3 face=3DHelvetica><span lang=3DPT-BR =
style=3D'font-size:12.0pt;font-family:
Helvetica'>Harvard School of Public Health</span></font><o:p></o:p></p>

<u1:p></u1:p>

<p class=3DMsoNormal =
style=3D'mso-margin-top-alt:auto;text-autospace:none'><font
size=3D3 face=3DHelvetica><span lang=3DPT-BR =
style=3D'font-size:12.0pt;font-family:
Helvetica'>Professor of Medicine, Harvard Medical =
School</span></font><o:p></o:p></p>

<u1:p></u1:p>

<p class=3DMsoNormal =
style=3D'mso-margin-top-alt:auto;text-autospace:none'><font
size=3D3 face=3DHelvetica><span lang=3DPT-BR =
style=3D'font-size:12.0pt;font-family:
Helvetica'>300 W. 23rd Street, Apt. 13K</span></font><o:p></o:p></p>

<u1:p></u1:p>

<p class=3DMsoNormal =
style=3D'mso-margin-top-alt:auto;text-autospace:none'><font
size=3D3 face=3DHelvetica><span lang=3DPT-BR =
style=3D'font-size:12.0pt;font-family:
Helvetica'>New York, NY, 10011</span></font><o:p></o:p></p>

<u1:p></u1:p>

<p class=3DMsoNormal =
style=3D'mso-margin-top-alt:auto;text-autospace:none'><font
size=3D3 face=3DHelvetica><span lang=3DPT-BR =
style=3D'font-size:12.0pt;font-family:
Helvetica'>Tel: 212 414 8646</span></font><o:p></o:p></p>

<u1:p></u1:p>

<p class=3DMsoNormal =
style=3D'mso-margin-top-alt:auto;text-autospace:none'><font
size=3D3 face=3DHelvetica><span lang=3DPT-BR =
style=3D'font-size:12.0pt;font-family:
Helvetica'>Email: <a href=3D"mailto:jdavid at hsph.harvard.edu"></a><a
href=3D"mailto:jdavid at hsph.harvard.edu">jdavid at hsph.harvard.edu</a></span=
></font><o:p></o:p></p>

<u1:p></u1:p>

<p class=3DMsoNormal =
style=3D'mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><font
size=3D3 face=3DHelvetica><span lang=3DPT-BR =
style=3D'font-size:12.0pt;font-family:
Helvetica'>&nbsp;</span></font><o:p></o:p></p>

<u1:p></u1:p>

<div>

<div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</div>

<div>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>On Sep 19, 2011, at 12:04 AM, Dr GR =
Rajasekariah wrote:<u1:p></u1:p></span><o:p></o:p></font></p>

</div>

<p class=3DMsoNormal style=3D'margin-bottom:12.0pt'><font size=3D3
face=3D"Times New Roman"><span lang=3DPT-BR =
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

<div>

<p class=3DMsoNormal style=3D'margin-bottom:12.0pt'><font size=3D3
face=3D"Times New Roman"><span lang=3DPT-BR =
style=3D'font-size:12.0pt'>Hello
EveryOne,<br>
I am responding to the topic on European VL Dog vaccine.<br>
It is a great challenge in devising a protective vaccine &nbsp;against =
visceral
leishmaniasis in dogs. This point equally applies the same challenge for =
human
situation.<br>
Because Th-2 response is so dominant during VL infection, modulating =
Th-2 into
Th-1 response is a big challenge to immunologists.<br>
<br>
Key points lies in the presentation of appropriate antigen in =
appropriate dose
to stimulate the &nbsp;Th-1 dependent protective immune response.<br>
I understand several vaccines are in the market and real efficacy of =
these vaccines
will come out once introduced to field conditions.<br>
<br>
I just wanted to inform you that we have a suitable antibody kit =
&nbsp;for
testing the immunopotentiation in dogs following vaccination of =
dogs.<br>
Our assay is based on the released promastigote antigens.<br>
It is a highly sensitive assay.<br>
Currently we supply reagents for &nbsp;determination of total IgG =
antibodies in
serum.<br>
If any particular group is interested then we are able to provide =
appropriate
reagent for detection of specific IgG2 and other isotype specific =
antibody
detection.<br>
Because our antibody detection ELISA is based on the exo-antigens such =
an ELISA
would be of exceptional type for measuring antibody response in =
vaccinated
animals.<br>
Highly suitable for diagnosing dogs responded to vaccines.<br>
<br>
Recently I came to know that some of &nbsp;commercial kits were found to =
be not
useful for detecting seroconversion in dogs vaccinated with FML vaccine
(Leish-Immune) in Brazil.<br>
Because we use released antigens in our kit, any such problems will =
overcome if
they use Canine Leish IgG CELISA (Manufacturer Cellabs Pty Ltd Brookvale =
NSW
Australia email <a href=3D"mailto:sales at cellabs.com.au"></a><a
href=3D"mailto:sales at cellabs.com.au">sales at cellabs.com.au</a>).<br>
If any one is interested to know more about our antibody detection ELISA =
based
on exo-antigens please contact us.<br>
<br>
This is for your kind information.<br>
<br>
Dr GR Rajasekariah<br>
Sydney<br>
Australia<br>
<a href=3D"mailto:raj at cellabs.com.au"></a><a =
href=3D"mailto:raj at cellabs.com.au">raj at cellabs.com.au</a><br>
<br>
<br>
<br>
<br>
<br>
<br>
----- Original Message ----- From: &lt;<a
href=3D"mailto:leish-l-request at lineu.icb.usp.br"></a><a
href=3D"mailto:leish-l-request at lineu.icb.usp.br">leish-l-request at lineu.ic=
b.usp.br</a>&gt;<br>
To: &lt;<a href=3D"mailto:leish-l at lineu.icb.usp.br"></a><a
href=3D"mailto:leish-l at lineu.icb.usp.br">leish-l at lineu.icb.usp.br</a>&gt;=
<br>
Sent: Wednesday, August 10, 2011 5:18 PM<br>
Subject: Leish-l Digest, Vol 44, Issue =
3<u1:p></u1:p></span><o:p></o:p></font></p>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Send Leish-l mailing list submissions =
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<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
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<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
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<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

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<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
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<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
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p>

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<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

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<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
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style=3D'font-size:12.0pt'>than &quot;Re: Contents of Leish-l =
digest...&quot;<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
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p>

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<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
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p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
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<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
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p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;1. European VL Dog Vaccine - =
CaniLeish?:
(jeffrey shaw)<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;2. Re: FW: Leishmaniasis Pathology =
Network
(Moazzem Hossain)<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;3. Re: FW: Leishmaniasis Pathology =
Network
(Moazzem Hossain)<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
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p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>----------------------------------------------=
------------------------<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
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p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Message: =
1<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Date: Tue, 9 Aug 2011 15:18:44 =
+0000<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>From: jeffrey shaw &lt;<a
href=3D"mailto:jayusp at hotmail.com"></a><a =
href=3D"mailto:jayusp at hotmail.com">jayusp at hotmail.com</a>&gt;<u1:p></u1:p=
></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Subject: [Leish-l] European VL Dog Vaccine -
CaniLeish?:<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>To: Leish-L &lt;<a
href=3D"mailto:leish-l at lineu.icb.usp.br"></a><a
href=3D"mailto:leish-l at lineu.icb.usp.br">leish-l at lineu.icb.usp.br</a>&gt;=
<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Message-ID: &lt;<a
href=3D"mailto:COL101-W1CDD4171D44B715B795E9CB200 at phx.gbl"></a><a
href=3D"mailto:COL101-W1CDD4171D44B715B795E9CB200 at phx.gbl">COL101-W1CDD41=
71D44B715B795E9CB200 at phx.gbl</a>&gt;<u1:p></u1:p></span><o:p></o:p></font=
></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Content-Type: text/plain; =
charset=3D&quot;windows-1252&quot;<u1:p></u1:p></span><o:p></o:p></font><=
/p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>CaniLeish?:<u1:p></u1:p></span><o:p></o:p></fo=
nt></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;The European Commission granted a
marketing authorisation valid throughout the European Union, for =
CaniLeish to
Virbac S.A. on 14/03/2011.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;This vaccine, CaniLeish?, will =
initially be
launched in Portugal at the end of the first half of 2011. This will be
followed rapidly by launches in other countries in the endemic area: =
Spain,
France, Greece and Italy (not in chronological order). This roll-out =
takes
account of the geographical prevalence of the disease and the time =
required to
build vaccine production up to full capacity. The launch in Northern =
European
countries from where there is a flow of summer visitors to the endemic =
area
will be part of a second =
phase.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;The basis of this vaccine are =
excreted
proteins plus a saponin adjuvant purified from Quil-A. Its efficacy was
determined in a 2 year open field =
trial.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;The vaccine is given to dogs as =
three
injections, three weeks apart, under the skin. The first injection can =
be given
from six months of age, the second injection is given three weeks later =
and the
third three weeks from the second one. Afterward a single ?booster? =
should be
given every year to maintain =
protection.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>-------------- next part =
--------------<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>An HTML attachment was =
scrubbed...<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>URL: &lt;<a
href=3D"http://lineu.icb.usp.br/pipermail/leish-l/attachments/20110809/f2=
404f5e/attachment-0001.htm"></a><a
href=3D"http://lineu.icb.usp.br/pipermail/leish-l/attachments/20110809/f2=
404f5e/attachment-0001.htm">http://lineu.icb.usp.br/pipermail/leish-l/att=
achments/20110809/f2404f5e/attachment-0001.htm</a>&gt;<u1:p></u1:p></span=
><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>------------------------------<u1:p></u1:p></s=
pan><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Message: =
2<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Date: Wed, 10 Aug 2011 13:07:17 =
+0600<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>From: Moazzem Hossain &lt;<a
href=3D"mailto:directordcbd at gmail.com"></a><a =
href=3D"mailto:directordcbd at gmail.com">directordcbd at gmail.com</a>&gt;<u1:=
p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Subject: Re: [Leish-l] FW: Leishmaniasis =
Pathology
Network<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>To: jeffrey shaw &lt;<a
href=3D"mailto:jayusp at hotmail.com"></a><a =
href=3D"mailto:jayusp at hotmail.com">jayusp at hotmail.com</a>&gt;,
&quot;Prof. Paul Kaye&quot;<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&lt;<a =
href=3D"mailto:paul.kaye at york.ac.uk"></a><a
href=3D"mailto:paul.kaye at york.ac.uk">paul.kaye at york.ac.uk</a>&gt;<u1:p></=
u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Cc: &quot;Prof. Dr. Moazzem Hossain&quot; =
&lt;<a
href=3D"mailto:profdrmoazzemhossain at gmail.com"></a><a
href=3D"mailto:profdrmoazzemhossain at gmail.com">profdrmoazzemhossain at gmail=
.com</a>&gt;,<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Leish-L &lt;<a =
href=3D"mailto:leish-l at lineu.icb.usp.br"></a><a
href=3D"mailto:leish-l at lineu.icb.usp.br">leish-l at lineu.icb.usp.br</a>&gt;=
<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Message-ID:<u1:p></u1:p></span><o:p></o:p></fo=
nt></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&lt;<a
href=3D"mailto:CAE-TCmS=3Di=3DWaT8cAeOXUJmot=3DKPvMQSLKar6CTfuUBK9M9tsUw@=
mail.gmail.com"></a><a
href=3D"mailto:CAE-TCmS=3Di=3DWaT8cAeOXUJmot=3DKPvMQSLKar6CTfuUBK9M9tsUw@=
mail.gmail.com">CAE-TCmS=3Di=3DWaT8cAeOXUJmot=3DKPvMQSLKar6CTfuUBK9M9tsUw=
@mail.gmail.com</a>&gt;<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Content-Type: text/plain; =
charset=3Dwindows-1252<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>10 Aug =
2011<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Dear Professor Paul =
Kaye,<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Thank you for your email. Please find =
attached our
supportive letter<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>of interest for Leishmaniasis Pathology =
Network.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Looking forward for your kind =
response.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Best =
regards.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>-- <u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>*Prof. Dr. Moazzem Hossain =
*<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Ex - Director Disease =
Control<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Ministry of Health &amp; Family =
Welfare<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Government of =
&nbsp;Bangladesh<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>*Mailing =
address*:<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Founder Chairman and Project =
Director<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Institute of Allergy &amp; Clinical =
Immunology of
Bangladesh (IACIB)<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Room 4 - 5 (2nd Floor), Green Super Market, =
Green Road<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Dhaka -1205, =
Bangladesh.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Phone:880-2-8115646 (O =
)<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbs=
p;880-1715038551(Mobile)<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Email: <a =
href=3D"mailto:directordcbd at gmail.com"></a><a
href=3D"mailto:directordcbd at gmail.com">directordcbd at gmail.com</a><u1:p></=
u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>On 8/9/11, jeffrey shaw &lt;<a
href=3D"mailto:jayusp at hotmail.com"></a><a =
href=3D"mailto:jayusp at hotmail.com">jayusp at hotmail.com</a>&gt;
wrote:<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Date: Tue, 9 Aug 2011 11:58:52 =
+0100<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>From: <a =
href=3D"mailto:paul.kaye at york.ac.uk"></a><a
href=3D"mailto:paul.kaye at york.ac.uk">paul.kaye at york.ac.uk</a><u1:p></u1:p=
></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Subject: Leishmaniasis Pathology =
Network<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;Dear =
all,<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;Invitation to participate =
in a
global pathology<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;network =
for<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;research and =
training in
leishmaniasis (LeishPathNet)<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;You may recall the Dormy =
House
meeting in 2008<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;and some =
of<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;the plans we =
put
forward? &nbsp;Over<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;the =
past<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;couple years, I =
have
also spoken more to a few of you about =
one<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;idea that =
was<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;formulated at =
Dormy, namely
of setting up a digital =
pathology<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;network. I =
have<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;also had =
numerous
discussions with the major =
equipment<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;manufacturers =
to see if<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;any of them =
would be
supportive of helping us to develop such =
an<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;initiative. =
&nbsp;There
have<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;been two =
major<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;develoments =
recently.
&nbsp;First,<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Carl =
Zeiss<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;is willing to =
work with
us to set up an integrated global =
digital<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;pathology<u1:p><=
/u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;network =
(providing a
significant financial and =
technical<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;contribution) =
and<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;second, the =
Wellcome
Trust is willing to review a pre-proposal =
to<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;fund =
the<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;initiative =
through their
new Biomedical Resources Grant =
scheme<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>(<a
href=3D"http://www.wellcome.ac.uk/Funding/Biomedical-science/Funding-sche=
mes/Strategic-awards-and-initiatives/wtdv031727.htm"></a><a
href=3D"http://www.wellcome.ac.uk/Funding/Biomedical-science/Funding-sche=
mes/Strategic-awards-and-initiatives/wtdv031727.htm">http://www.wellcome.=
ac.uk/Funding/Biomedical-science/Funding-schemes/Strategic-awards-and-ini=
tiatives/wtdv031727.htm</a>)<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;.<u1:p></u1:p></=
span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;I have attached an outline =
of the
project that<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;I had sent =
to<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;the Trust for =
their
initial views, which I think is =
reasonably<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;self-explanatory=
.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;They =
appeared very<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;enthusiastic! =
&nbsp;The
main<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;question now is =
whether
enough of<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;you are still
supportive? [ I will also be sending this email =
to<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;others, but =
please feel
free to circulate ]<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;I think =
the<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;proj=
ect will
be<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;chal=
lenging,
but success could have a real impact on the way =
we<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;cond=
uct<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;busi=
ness.
&nbsp;It should serve not only as a vehicle to =
enhance<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;rese=
arch in<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;leis=
hmaniasis,
but the model would be equally applicable =
across<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;a =
broad range<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;of =
diseases
and global challenges (with leishmaniasis =
setting<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;the =
pace).<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;If we wish =
to<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;proc=
eed, the
requirements<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;are =
that we
submit a pre-proposal to the Trust by Oct 18th =
2011.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This=

pre-proposal is short (4 sections of 350 words) =
and<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;requ=
ires<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;lett=
ers of
support from the community.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;If you =
are<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;supp=
ortive
of the idea that<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;we =
try to
take this forward (and there is plenty of scope =
for<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;late=
r
iteration<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;of =
the
detail), I would be grateful if you could please =
provide<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;me =
with a<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;lett=
er of support
by September<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbs=
p;&nbsp;12th<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbs=
p;&nbsp;2011,
indicating whether you would like to be a =
network<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;part=
ner if
the bid<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;is
successful. &nbsp;You could<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;also=
 be<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;supp=
ortive
but not wish to become directly involved at =
this<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;stag=
e, and
such<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;lett=
ers are
equally valuable. Your letter might also stress =
the<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;adde=
d value<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;that=
 the
network could provide, its importance for research =
and<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;trai=
ning
and/or<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;for
progressing the translational =
agenda.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;It =
would
also be an opportunity to indicate whether =
your<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;grou=
p (or<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;inst=
itute,
if multiple groups) would be interested in bidding =
to<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;be =
one of the<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;init=
ial
?designated laboratories?.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;If there =
is<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;suff=
icient
support to<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;proc=
eed and
if subsequently the pre-proposal is successful =
(we<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;will=
 know on
22nd<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Nov)=
, then I
will need a few volunteers to help finalise =
the<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;full=

proposal,<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;whic=
h will
be due on Jan 26th 2012.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A =
funding
decision will be made on May =
26th<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2012=
.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;Best =
wishes<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;and =
of
course I am happy to<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;disc=
uss any
points further (though I will be out of the UK =
from<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Aug =
10 ?Sept<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;12)<=
u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;Paul<u1:p></u1:p></span><o:p=
></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;--<u1:p></u1:p></span><o:p><=
/o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Professor Paul Kaye, Ph.D., =
FRCPath.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Deputy Dean (Research), Hull York Medical =
School, and<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Director, Centre for Immunology and =
Infection<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Department of Biology and Hull York Medical =
School<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>University of =
York<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Wentworth =
Way<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>York YO10 =
5YW<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>United =
Kingdom<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Tel: &nbsp;+44 (0)1904 =
328840<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Fax: &nbsp;+44 (0)1904 =
328844<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Email: <a =
href=3D"mailto:paul.kaye at york.ac.uk"></a><a
href=3D"mailto:paul.kaye at york.ac.uk">paul.kaye at york.ac.uk</a> &lt;<a
href=3D"mailto:paul.kaye at york.ac.uk"></a><a =
href=3D"mailto:paul.kaye at york.ac.uk">mailto:paul.kaye at york.ac.uk</a>&gt;<=
u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Centre Administrator and PA: Elizabeth =
Greensted<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Tel: &nbsp;01904 =
328845<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Email: <a =
href=3D"mailto:liz.greensted at york.ac.uk"></a><a
href=3D"mailto:liz.greensted at york.ac.uk">liz.greensted at york.ac.uk</a> =
&lt;<a
href=3D"mailto:liz.greensted at york.ac.uk"></a><a
href=3D"mailto:liz.greensted at york.ac.uk">mailto:liz.greensted at york.ac.uk<=
/a>&gt;<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Centre Email: <a =
href=3D"mailto:cii at york.ac.uk"></a><a
href=3D"mailto:cii at york.ac.uk">cii at york.ac.uk</a> &lt;<a
href=3D"mailto:cii at york.ac.uk"></a><a =
href=3D"mailto:cii at york.ac.uk">mailto:cii at york.ac.uk</a>&gt;<u1:p></u1:p>=
</span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Centre website: <a =
href=3D"http://www.york.ac.uk/cii"></a><a
href=3D"http://www.york.ac.uk/cii">http://www.york.ac.uk/cii</a><u1:p></u=
1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Times Higher Education University of the Year =
2010<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Email disclaimer: <a
href=3D"http://www.york.ac.uk/docs/disclaimer/email.htm"></a><a
href=3D"http://www.york.ac.uk/docs/disclaimer/email.htm">http://www.york.=
ac.uk/docs/disclaimer/email.htm</a><u1:p></u1:p></span><o:p></o:p></font>=
</p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>------------------------------<u1:p></u1:p></s=
pan><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Message: =
3<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Date: Wed, 10 Aug 2011 13:06:47 =
+0600<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>From: Moazzem Hossain &lt;<a
href=3D"mailto:directordcbd at gmail.com"></a><a =
href=3D"mailto:directordcbd at gmail.com">directordcbd at gmail.com</a>&gt;<u1:=
p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Subject: Re: [Leish-l] FW: Leishmaniasis =
Pathology
Network<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>To: jeffrey shaw &lt;<a
href=3D"mailto:jayusp at hotmail.com"></a><a =
href=3D"mailto:jayusp at hotmail.com">jayusp at hotmail.com</a>&gt;,
&quot;Prof. Paul Kaye&quot;<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&lt;<a =
href=3D"mailto:paul.kaye at york.ac.uk"></a><a
href=3D"mailto:paul.kaye at york.ac.uk">paul.kaye at york.ac.uk</a>&gt;<u1:p></=
u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Cc: &quot;Prof. Dr. Moazzem Hossain&quot; =
&lt;<a
href=3D"mailto:profdrmoazzemhossain at gmail.com"></a><a
href=3D"mailto:profdrmoazzemhossain at gmail.com">profdrmoazzemhossain at gmail=
.com</a>&gt;,<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Leish-L &lt;<a =
href=3D"mailto:leish-l at lineu.icb.usp.br"></a><a
href=3D"mailto:leish-l at lineu.icb.usp.br">leish-l at lineu.icb.usp.br</a>&gt;=
<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Message-ID:<u1:p></u1:p></span><o:p></o:p></fo=
nt></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&lt;<a
href=3D"mailto:CAE-TCmQNUkZdNE5w+Z20bjLC-=3DvvV9BCP6OLOm9f6RV-BfpXvA at mail=
.gmail.com"></a><a
href=3D"mailto:CAE-TCmQNUkZdNE5w+Z20bjLC-=3DvvV9BCP6OLOm9f6RV-BfpXvA at mail=
.gmail.com">CAE-TCmQNUkZdNE5w+Z20bjLC-=3DvvV9BCP6OLOm9f6RV-BfpXvA at mail.gm=
ail.com</a>&gt;<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Content-Type: text/plain; =
charset=3D&quot;windows-1252&quot;<u1:p></u1:p></span><o:p></o:p></font><=
/p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>10 Aug =
2011<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Dear Professor Paul =
Kaye,<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Thank you for your email. Please find =
attached our
supportive letter<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>of interest for Leishmaniasis Pathology =
Network.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Looking forward for your kind =
response.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Best =
regards.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>-- <u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>*Prof. Dr. Moazzem Hossain =
*<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Ex - Director Disease =
Control<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Ministry of Health &amp; Family =
Welfare<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Government of =
&nbsp;Bangladesh<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>*Mailing =
address*:<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Founder Chairman and Project =
Director<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Institute of Allergy &amp; Clinical =
Immunology of
Bangladesh (IACIB)<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Room 4 - 5 (2nd Floor), Green Super Market, =
Green Road<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Dhaka -1205, =
Bangladesh.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Phone:880-2-8115646 (O =
)<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbs=
p;880-1715038551(Mobile)<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Email: <a =
href=3D"mailto:directordcbd at gmail.com"></a><a
href=3D"mailto:directordcbd at gmail.com">directordcbd at gmail.com</a><u1:p></=
u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>On 8/9/11, jeffrey shaw &lt;<a
href=3D"mailto:jayusp at hotmail.com"></a><a =
href=3D"mailto:jayusp at hotmail.com">jayusp at hotmail.com</a>&gt;
wrote:<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Date: Tue, 9 Aug 2011 11:58:52 =
+0100<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>From: <a =
href=3D"mailto:paul.kaye at york.ac.uk"></a><a
href=3D"mailto:paul.kaye at york.ac.uk">paul.kaye at york.ac.uk</a><u1:p></u1:p=
></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Subject: Leishmaniasis Pathology =
Network<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;Dear =
all,<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;Invitation to participate =
in a
global pathology<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;network =
for<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;research and =
training in
leishmaniasis (LeishPathNet)<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;You may recall the Dormy =
House
meeting in 2008<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;and some =
of<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;the plans we =
put
forward? &nbsp;Over<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;the =
past<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;couple years, I =
have
also spoken more to a few of you about =
one<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;idea that =
was<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;formulated at =
Dormy,
namely of setting up a digital =
pathology<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;network. I =
have<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;also had =
numerous
discussions with the major =
equipment<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;manufacturers =
to see if<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;any of them =
would be
supportive of helping us to develop such =
an<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;initiative. =
&nbsp;There
have<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;been two =
major<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;develoments =
recently.
&nbsp;First,<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Carl =
Zeiss<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;is willing to =
work with
us to set up an integrated global =
digital<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;pathology<u1:p><=
/u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;network =
(providing a
significant financial and =
technical<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;contribution) =
and<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;second, the =
Wellcome
Trust is willing to review a pre-proposal =
to<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;fund =
the<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;initiative =
through their
new Biomedical Resources Grant =
scheme<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>(<a
href=3D"http://www.wellcome.ac.uk/Funding/Biomedical-science/Funding-sche=
mes/Strategic-awards-and-initiatives/wtdv031727.htm"></a><a
href=3D"http://www.wellcome.ac.uk/Funding/Biomedical-science/Funding-sche=
mes/Strategic-awards-and-initiatives/wtdv031727.htm">http://www.wellcome.=
ac.uk/Funding/Biomedical-science/Funding-schemes/Strategic-awards-and-ini=
tiatives/wtdv031727.htm</a>)<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;.<u1:p></u1:p></=
span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;I have attached an outline =
of the
project that<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;I had sent =
to<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;the Trust for =
their
initial views, which I think is =
reasonably<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;self-explanatory=
.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;They =
appeared very<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;enthusiastic! =
&nbsp;The
main<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;question now is =
whether
enough of<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;you are still
supportive? [ I will also be sending this email =
to<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;others, but =
please feel
free to circulate ]<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;I think =
the<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;proj=
ect will
be<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;chal=
lenging,
but success could have a real impact on the way =
we<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;cond=
uct<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;busi=
ness.
&nbsp;It should serve not only as a vehicle to =
enhance<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;rese=
arch in<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;leis=
hmaniasis,
but the model would be equally applicable =
across<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;a =
broad range<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;of =
diseases
and global challenges (with leishmaniasis =
setting<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;the =
pace).<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;If we wish =
to<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;proc=
eed, the
requirements<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;are =
that we
submit a pre-proposal to the Trust by Oct 18th =
2011.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;This=

pre-proposal is short (4 sections of 350 words) =
and<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;requ=
ires<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;lett=
ers of
support from the community.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;If you =
are<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;supp=
ortive
of the idea that<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;we =
try to
take this forward (and there is plenty of scope =
for<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;late=
r iteration<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;of =
the
detail), I would be grateful if you could please =
provide<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;me =
with a<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;lett=
er of
support by September<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbs=
p;&nbsp;12th<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbs=
p;&nbsp;2011,
indicating whether you would like to be a =
network<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;part=
ner if
the bid<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;is =
successful.
&nbsp;You could<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;also=
 be<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;supp=
ortive
but not wish to become directly involved at =
this<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;stag=
e, and
such<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;lett=
ers are
equally valuable. Your letter might also stress =
the<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;adde=
d value<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;that=
 the network
could provide, its importance for research =
and<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;trai=
ning
and/or<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;for
progressing the translational =
agenda.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;It =
would
also be an opportunity to indicate whether =
your<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;grou=
p (or<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;inst=
itute,
if multiple groups) would be interested in bidding =
to<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;be =
one of the<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;init=
ial
?designated laboratories?.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;If there =
is<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;suff=
icient
support to<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;proc=
eed and
if subsequently the pre-proposal is successful =
(we<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;will=
 know on
22nd<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Nov)=
, then I
will need a few volunteers to help finalise =
the<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;full=

proposal,<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;whic=
h will
be due on Jan 26th 2012.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;A =
funding
decision will be made on May =
26th<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;2012=
.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;Best =
wishes<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;and =
of
course I am happy to<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;disc=
uss any
points further (though I will be out of the UK =
from<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Aug =
10 ?Sept<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;12)<=
u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;Paul<u1:p></u1:p></span><o:p=
></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>&nbsp;&nbsp;&nbsp;--<u1:p></u1:p></span><o:p><=
/o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Professor Paul Kaye, Ph.D., =
FRCPath.<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Deputy Dean (Research), Hull York Medical =
School, and<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Director, Centre for Immunology and =
Infection<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Department of Biology and Hull York Medical =
School<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>University of =
York<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Wentworth =
Way<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>York YO10 =
5YW<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>United =
Kingdom<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Tel: &nbsp;+44 (0)1904 =
328840<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Fax: &nbsp;+44 (0)1904 =
328844<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Email: <a =
href=3D"mailto:paul.kaye at york.ac.uk"></a><a
href=3D"mailto:paul.kaye at york.ac.uk">paul.kaye at york.ac.uk</a> &lt;<a
href=3D"mailto:paul.kaye at york.ac.uk"></a><a =
href=3D"mailto:paul.kaye at york.ac.uk">mailto:paul.kaye at york.ac.uk</a>&gt;<=
u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Centre Administrator and PA: Elizabeth =
Greensted<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Tel: &nbsp;01904 =
328845<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Email: <a =
href=3D"mailto:liz.greensted at york.ac.uk"></a><a
href=3D"mailto:liz.greensted at york.ac.uk">liz.greensted at york.ac.uk</a> =
&lt;<a
href=3D"mailto:liz.greensted at york.ac.uk"></a><a
href=3D"mailto:liz.greensted at york.ac.uk">mailto:liz.greensted at york.ac.uk<=
/a>&gt;<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Centre Email: <a =
href=3D"mailto:cii at york.ac.uk"></a><a
href=3D"mailto:cii at york.ac.uk">cii at york.ac.uk</a> &lt;<a
href=3D"mailto:cii at york.ac.uk"></a><a =
href=3D"mailto:cii at york.ac.uk">mailto:cii at york.ac.uk</a>&gt;<u1:p></u1:p>=
</span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Centre website: <a =
href=3D"http://www.york.ac.uk/cii"></a><a
href=3D"http://www.york.ac.uk/cii">http://www.york.ac.uk/cii</a><u1:p></u=
1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Times Higher Education University of the Year =
2010<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>Email disclaimer: <a
href=3D"http://www.york.ac.uk/docs/disclaimer/email.htm"></a><a
href=3D"http://www.york.ac.uk/docs/disclaimer/email.htm">http://www.york.=
ac.uk/docs/disclaimer/email.htm</a><u1:p></u1:p></span><o:p></o:p></font>=
</p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'><u1:p>&nbsp;</u1:p></span><o:p></o:p></font></=
p>

</blockquote>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>-------------- next part =
--------------<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
lang=3DPT-BR
style=3D'font-size:12.0pt'>A non-text attachment was =
scrubbed...<u1:p></u1:p></span><o:p></o:p></font></p>

</blockquote>

<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
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<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
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<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
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<blockquote style=3D'margin-top:5.0pt;margin-bottom:5.0pt'>

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<p class=3DMsoNormal><font size=3D3 face=3D"Times New Roman"><span =
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