No subject
Thu Feb 26 03:28:06 BRT 2009
elimina=E7=E3o de c=E3es, ponha-se no lugar do morador da =E1rea =
end=EAmica e responda: "Eu aceitaria ter c=E3es positivos perto de mim, =
contaminando os insetos e pondo em risco meus filhos?"."): "Before =
deciding the interruption of dog culling, put yourself in the shoes of =
the inhabitant of endemic area and answer: "Would I accept to have =
positive dogs near me, contaminating insects and endangering my kids?"".
Sincerely yours
Carlos Brisola Marcondes
----- Original Message -----=20
From: Carlos Costa=20
To: Carlos Brisola Marcondes=20
Cc: Jaclamothe at aol.com ; leish-l at lineu.icb.usp.br=20
Sent: Thursday, April 09, 2009 10:02 AM
Subject: Re: [Leish-l] Back to business
It is amazing to see the differences in cultures between Brazil and =
Europe. Here will we are scared and kill every seropositive dog, But =
there dogs are treated and human VL have a much lower incidence. This is =
a subject much beyond Science.
2009/4/7 Carlos Brisola Marcondes <cbrisola at mbox1.ufsc.br>
Dear all
I would remind that the utilization for dogs of drugs utilized =
for humans was forbidden in the last year by federal government.
Would it be viable to treat thousands of dogs in the huge (and =
variable) endemic area of Brazil, which are replaced very quickly? Would =
any of us like to have positive dogs being treated in our neighbourhood?
Best wishes
Carlos Brisola Marcondes----- Original Message -----=20
From: Jaclamothe at aol.com=20
To: killickendrick at wanadoo.fr ; leish-l at lineu.icb.usp.br=20
Sent: Monday, April 06, 2009 7:55 PM
Subject: Re: [Leish-l] Back to business
Dans un e-mail dat=E9 du 04/04/2009 19:55:11 Paris, Madrid (heure =
d'=E9t=E9), killickendrick at wanadoo.fr a =E9crit :
Surely Jacques is not recommending allopuriol alone as =
treatment? I seem to remember a study that showed this was not a good =
idea.
In France, Glucantime is geverally the answer to CanL with =
allopurinol as well. Dogs are not destroyed by law. Medical doctors =
question the use of Glucantime because of the risk of drug resustance.
By the way, 'vaccinated' dogs in Brazil are presumably =
seropositive. if so, they should be killed!
Bob Killick-Kendrick
Allopurinol alone has a great advantage , the risk of =
creating resistance transmitted to humans is neglectable (compared with =
antimonials or ampho b )=20
Pr Slappedel in Netherland has begun and had good results (80% =
long term efficacy) . The paper you mention was published in 99 . It =
was a comparative study , but in the group allopurinol alone, dogs =
were only treated 1 month... (its difficult to make a clinical studies =
with dogs belonging to owners) It is for me impossible to make any =
conclusion from these results even if it has been done...
In Greece , Pr Koutinas in a 4 months study has 100% improvement =
and 50% of clinical cure . They have also excellent results in the most =
severe forms of cl (renal disease) . Gad Baneth uses also this treatment =
in Israel=20
In the american focus , ive treated and closely followed around 20 =
dogs (Glucantime was not available , and i didnt want to use it) and =
it was a succes. The only problem is that clinical cure is reached after =
a longer time than with the classic association Glucantime allopurinol. =
But dogs dont go to work on mondays.=20
There is an emerging consensus in the vet community to avoid the =
use of Glucantime and amphotericin B (recent papers of the vet leish =
group in Trends in Parasitology)
Regards from France=20
Jacques Lamothe
-------------------------------------------------------------------------=
-
_______________________________________________
Leish-l mailing list
Leish-l at lineu.icb.usp.br
http://lineu.icb.usp.br/cgi-bin/mailman/listinfo/leish-l
_______________________________________________
Leish-l mailing list
Leish-l at lineu.icb.usp.br
http://lineu.icb.usp.br/cgi-bin/mailman/listinfo/leish-l
--=20
Dr. Carlos Henrique Nery Costa.
Coordenador Executivo - Rede Nordeste de Biotecnologia
Diretor Geral - Instituto de Doen=E7as Tropicais Natan Portella
Universidade Federal do Piau=ED
Rua Artur de Vasconcelos 151-Sul
64.001-450 Teresina-PI=20
Brasil
Telefones: IDTNP:+55 86 3221-3413;=20
Celular: +55 86 9985-6132; Fax: +55 86 3222-3248
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charset="iso-8859-1"
Content-Transfer-Encoding: quoted-printable
<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN">
<HTML><HEAD>
<META http-equiv=3DContent-Type content=3D"text/html; =
charset=3Diso-8859-1">
<META content=3D"MSHTML 6.00.5730.11" name=3DGENERATOR>
<STYLE></STYLE>
</HEAD>
<BODY bgColor=3D#cfcfcf>
<DIV><FONT face=3DArial>Dear all,</FONT></DIV>
<DIV><FONT face=3DArial>I would send to you a comment from a footnote in =
my new=20
book ("Doen=E7as transmitidas e causadas pro =
artr=F3podes"):</FONT></DIV>
<DIV><FONT face=3DArial>From Portuguese ("<FONT size=3D3><SPAN=20
style=3D"FONT-SIZE: 8pt; FONT-FAMILY: 'Arial','sans-serif'; =
mso-bidi-font-size: 12.0pt; mso-fareast-font-family: 'Times New Roman'; =
mso-ansi-language: PT-BR; mso-fareast-language: PT-BR; =
mso-bidi-language: AR-SA">Antes=20
de tomar a decis=E3o de suspender a elimina=E7=E3o de c=E3es, ponha-se =
no lugar do=20
morador da =E1rea end=EAmica e responda: =93Eu aceitaria ter c=E3es =
positivos perto de=20
mim, contaminando os insetos e pondo em risco meus filhos?=94.</SPAN>"): =
"Before=20
deciding the interruption of dog culling, put yourself in the shoes =
of the=20
inhabitant of endemic area and answer: "Would I accept to have positive =
dogs=20
near me, contaminating insects and endangering my =
kids?"".</FONT></FONT></DIV>
<DIV><FONT face=3DArial></FONT> </DIV>
<DIV><FONT face=3DArial>Sincerely yours</FONT></DIV>
<DIV><FONT face=3DArial size=3D2>Carlos Brisola Marcondes</FONT></DIV>
<BLOCKQUOTE=20
style=3D"PADDING-RIGHT: 0px; PADDING-LEFT: 5px; MARGIN-LEFT: 5px; =
BORDER-LEFT: #000000 2px solid; MARGIN-RIGHT: 0px">
<DIV style=3D"FONT: 10pt arial">----- Original Message ----- </DIV>
<DIV=20
style=3D"BACKGROUND: #e4e4e4; FONT: 10pt arial; font-color: =
black"><B>From:</B>=20
<A title=3Dchncosta at gmail.com =
href=3D"mailto:chncosta at gmail.com">Carlos Costa</A>=20
</DIV>
<DIV style=3D"FONT: 10pt arial"><B>To:</B> <A =
title=3Dcbrisola at mbox1.ufsc.br=20
href=3D"mailto:cbrisola at mbox1.ufsc.br">Carlos Brisola Marcondes</A> =
</DIV>
<DIV style=3D"FONT: 10pt arial"><B>Cc:</B> <A =
title=3DJaclamothe at aol.com=20
href=3D"mailto:Jaclamothe at aol.com">Jaclamothe at aol.com</A> ; <A=20
title=3Dleish-l at lineu.icb.usp.br=20
href=3D"mailto:leish-l at lineu.icb.usp.br">leish-l at lineu.icb.usp.br</A> =
</DIV>
<DIV style=3D"FONT: 10pt arial"><B>Sent:</B> Thursday, April 09, 2009 =
10:02=20
AM</DIV>
<DIV style=3D"FONT: 10pt arial"><B>Subject:</B> Re: [Leish-l] Back to=20
business</DIV>
<DIV><BR></DIV>
<DIV>It is amazing to see the differences in cultures between =
Brazil and=20
Europe. Here will we are scared and kill every seropositive dog, But =
there=20
dogs are treated and human VL have a much lower incidence. This =
is a=20
subject much beyond Science.<BR><BR></DIV>
<DIV class=3Dgmail_quote>2009/4/7 Carlos Brisola Marcondes <SPAN =
dir=3Dltr><<A=20
=
href=3D"mailto:cbrisola at mbox1.ufsc.br">cbrisola at mbox1.ufsc.br</A>></SP=
AN><BR>
<BLOCKQUOTE class=3Dgmail_quote=20
style=3D"PADDING-LEFT: 1ex; MARGIN: 0px 0px 0px 0.8ex; BORDER-LEFT: =
#ccc 1px solid">
<DIV style=3D"FONT-SIZE: 10pt; COLOR: #000000; FONT-FAMILY: Arial"=20
bgcolor=3D"#cfcfcf">
<DIV>Dear all</DIV>
<DIV> I would remind that the utilization for dogs of =
drugs=20
utilized for humans was forbidden in the last year by federal=20
government.</DIV>
<DIV> Would it be viable to treat thousands of dogs in =
the huge=20
(and variable) endemic area of Brazil, which are replaced very =
quickly?=20
Would any of us like to have positive dogs being treated in our =
neighbourhood?</DIV>
<DIV> </DIV>
<DIV>Best wishes</DIV>
<DIV>Carlos Brisola Marcondes----- Original Message ----- </DIV>
<BLOCKQUOTE=20
style=3D"PADDING-RIGHT: 0px; PADDING-LEFT: 5px; MARGIN-LEFT: 5px; =
BORDER-LEFT: #000000 2px solid; MARGIN-RIGHT: 0px">
<DIV style=3D"BACKGROUND: #e4e4e4; FONT: 10pt arial"><B>From:</B> =
<A=20
title=3DJaclamothe at aol.com href=3D"mailto:Jaclamothe at aol.com"=20
target=3D_blank>Jaclamothe at aol.com</A> </DIV>
<DIV class=3Dim>
<DIV style=3D"FONT: 10pt arial"><B>To:</B> <A=20
title=3Dkillickendrick at wanadoo.fr =
href=3D"mailto:killickendrick at wanadoo.fr"=20
target=3D_blank>killickendrick at wanadoo.fr</A> ; <A=20
title=3Dleish-l at lineu.icb.usp.br =
href=3D"mailto:leish-l at lineu.icb.usp.br"=20
target=3D_blank>leish-l at lineu.icb.usp.br</A> </DIV></DIV>
<DIV style=3D"FONT: 10pt arial"><B>Sent:</B> Monday, April 06, =
2009 7:55=20
PM</DIV>
<DIV class=3Dim>
<DIV style=3D"FONT: 10pt arial"><B>Subject:</B> Re: [Leish-l] Back =
to=20
business</DIV>
<DIV><BR></DIV></DIV>
<DIV>
<DIV></DIV>
<DIV class=3Dh5><FONT face=3DArial color=3D#000000 size=3D2>
<DIV>
<DIV>
<DIV>Dans un e-mail dat=E9 du 04/04/2009 19:55:11 Paris, Madrid =
(heure=20
d'=E9t=E9), <A href=3D"mailto:killickendrick at wanadoo.fr"=20
target=3D_blank>killickendrick at wanadoo.fr</A> a =E9crit :</DIV>
<BLOCKQUOTE=20
style=3D"PADDING-LEFT: 5px; MARGIN-LEFT: 5px; BORDER-LEFT: blue =
2px solid"><FONT=20
style=3D"BACKGROUND-COLOR: transparent" face=3DArial =
color=3D#000000 size=3D2>
<DIV>Surely Jacques is not recommending allopuriol alone as =
treatment? I=20
seem to remember a study that showed this was not a good =
idea.</DIV>
<DIV>In France, Glucantime is geverally the answer to CanL with=20
allopurinol as well. Dogs are not destroyed by law. Medical =
doctors=20
question the use of Glucantime because of the risk of drug=20
resustance.</DIV>
<DIV> By the way, 'vaccinated' dogs in Brazil =
are=20
presumably seropositive. if so, they should be killed!</DIV>
<DIV> Bob=20
Killick-Kendrick</DIV></FONT></BLOCKQUOTE></DIV>
=
<DIV></DIV> &n=
bsp; Allopurinol=20
alone has a great advantage , the risk of creating resistance =
transmitted=20
to humans is neglectable (compared with antimonials or ampho b ) =
</DIV>
<DIV>Pr Slappedel in Netherland has begun and had good =
results=20
(80% long term efficacy) . The paper you mention was =
published in=20
99 . It was a comparative study , but in the group =
allopurinol=20
alone, dogs were only treated 1 month... (its =
difficult to=20
make a clinical studies with dogs belonging to owners) It is for =
me=20
impossible to make any conclusion from these results =
even if it=20
has been done...</DIV>
<DIV> </DIV>
<DIV>In Greece , Pr Koutinas in a 4 months study has 100%=20
improvement and 50% of clinical cure . They have also excellent =
results in=20
the most severe forms of cl (renal disease) . Gad Baneth uses also =
this=20
treatment in Israel </DIV>
<DIV>In the american focus , ive treated and closely followed =
around 20=20
dogs (Glucantime was not available , and i didnt want =
to use=20
it) and it was a succes. The only problem is that clinical =
cure is=20
reached after a longer time than with the classic association =
Glucantime=20
allopurinol. But dogs dont go to work on mondays. </DIV>
<DIV> </DIV>
<DIV>There is an emerging consensus in the vet community to avoid =
the use=20
of Glucantime and amphotericin B (recent papers of the vet leish =
group in=20
Trends in Parasitology)</DIV>
<DIV> </DIV>
<DIV> </DIV>
<DIV>Regards from France </DIV>
<DIV> </DIV>
<DIV><FONT lang=3D1 face=3DArial size=3D2>Jacques=20
Lamothe</FONT></DIV></FONT></DIV></DIV>
<P>
<HR>
<DIV class=3Dim>
<P></P>_______________________________________________<BR>Leish-l =
mailing=20
list<BR><A href=3D"mailto:Leish-l at lineu.icb.usp.br"=20
target=3D_blank>Leish-l at lineu.icb.usp.br</A><BR><A=20
href=3D"http://lineu.icb.usp.br/cgi-bin/mailman/listinfo/leish-l"=20
=
target=3D_blank>http://lineu.icb.usp.br/cgi-bin/mailman/listinfo/leish-l<=
/A><BR></DIV>
<P></P>
=
<P></P></BLOCKQUOTE></DIV><BR>___________________________________________=
____<BR>Leish-l=20
mailing list<BR><A=20
=
href=3D"mailto:Leish-l at lineu.icb.usp.br">Leish-l at lineu.icb.usp.br</A><BR>=
<A=20
href=3D"http://lineu.icb.usp.br/cgi-bin/mailman/listinfo/leish-l"=20
=
target=3D_blank>http://lineu.icb.usp.br/cgi-bin/mailman/listinfo/leish-l<=
/A><BR><BR></BLOCKQUOTE></DIV><BR><BR=20
clear=3Dall><BR>-- <BR>Dr. Carlos Henrique Nery Costa.<BR>Coordenador =
Executivo=20
- Rede Nordeste de Biotecnologia<BR>Diretor Geral - Instituto de =
Doen=E7as=20
Tropicais Natan Portella<BR>Universidade Federal do Piau=ED<BR>Rua =
Artur de=20
Vasconcelos 151-Sul<BR>64.001-450 Teresina-PI <BR>Brasil<BR>Telefones: =
IDTNP:+55 86 3221-3413; <BR>Celular: +55 86 9985-6132; Fax: +55 86=20
3222-3248<BR></BLOCKQUOTE></BODY></HTML>
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