Painful antimonials

Marcia Hueb mhueb at
Tue Nov 14 18:12:24 BRST 2000

Dear Dr. Davidson

I agree with Dr. Reynaldo, I prefer intravenous injections, especially for
Whatever, I am surprised about your message. We normally have Glucantime to
use in our service and when the patients cannot stay at the hospital they
prefer to use intramuscular injections. They rarely claim about local pain.
Some time ago we had to use stibogluconate from China and the patients with
intramuscular injections asked for us to change for intravenous injections.
Only at that time we had this kind of problem.
I think we have to discuss why some solutions are more painful than others.

Marcia Hueb
University Hospital Julio Muller
Cuiabá, Mato Grosso, Brazil

----- Original Message -----
From: Davidson, Robert N <r.n.davidson at>
To: Multiple recipients of list <leish-l at>
Sent: Friday, November 10, 2000 2:48 PM
Subject: Painful antimonials

> Dear Colleagues,
> as you'll all know, intramuscular injections of sodium stibogluconate or
> meglumine antimoniate are very painful, especially in children and in kala
> azar patients with wasted muscles. Does anyone know if lignocaine (in USA:
> lidocaine) may be mixed in the same syringe with antimonials, or will it
> have an interaction?
> yours, Robert Davidson

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