URGENT FOR LEISHMANIA TOO!

[Stephen Beverley]

Al,

I'm certainly willing to write a letter.  It might help to have a bit more 
of outline of what the preliminary application will include though.  Will 
FAX suffice by your deadline?

As to things to include, there are a lot of obvious things that I won't 
bother to suggest.   I think the informational side of things is coming 
along nicely.  However, the physical side of things, eg distribution of 
'genome' resources such as libraries, gridded out libraries, published 
clone collections, etc. is another story.  this would be my own personal 
priority.

         To that end, we have made arrangements with Genome Systems Inc. 
here in St. Louis to make a gridded Friedlin V1 and L. donovani 1s2D cLHYG 
library available, also our complete set of sequenced GSS clones suitable 
for microarraying.    We have had very good experience with our gridded 
library, no problems with mixed clones as yet.   Once they are all set and 
in place, I'll circulate an annoucement to people.  Their costs are not 
very high and it saves a ton of time and infrastructure for us poor academics.

Best regards,

Steve


My own personal priority would include arrangements forAt 01:57 PM 2/7/00 
-0200, you wrote:
>Dear Colleagues,
>
>re:  Leishmania Genome Project
>
>You may be aware that the Wellcome Trust has announced a functional
>genomics initiative (http://www.wellcome.ac.uk/en/1/biosfggen.html).
>This is a golden opportunity to make an application to upgrade the
>Leishmania major genome project bioinformatics resources available to
>all via the web and/or ftp. In this context, I am keeping in close
>contact with our fellow T. brucei and T. cruzi genome projects, with a
>view to integrating the three at some date in the near future.
>
>If successful, funding would be for 5 years in the first instance, with
>review in year 4.
>
>The preliminary application has to be in by **** this Friday: 11th
>February ****. At this stage, I would like to ask whether you would be
>willing to provide a letter of support for the application, mentioning
>the usefulness/accessibility of current data and how an integrated
>database would influence your future research and the need to upgrade
>analysis procedures.  It might also be useful to draw attention to the
>comparative genomics/proteomics potential of such a database.
>
>Your letter would have to reach me by **** Thursday 10th February ****.
>I can accept most forms of email attachment but nice headed paper is
>appreciated (and preferably signed as well!). It was clear from a
>Wellcome Trust databases meeting last week that our getting the funding
>will depend heavily on the level of research community support.  A large
>number of such letters are ESSENTIAL to the application (i.e. it won't
>be funded without them).
>
>I would also appreciate any views you have on resources that you would
>like to be available. I will try to amalgamate as many of these as
>possible in the final proposal.
>
>If you could send your letter to me either as an email attachment on
>headed paper, or by fax to +44-1223-49 49 19, that would be very much
>appreciated!  They MUST arrive here by Thursday...!
>
>With many thanks in advance,
>
>Cheers,
>al
>
>
>--
>
>===================================
>Al Ivens
>Sanger Centre
>Wellcome Trust Genome Campus
>Hinxton
>Cambs. CB10 1SA
>UK
>
>Tel -44-1223- 49 49 55 (Office: E2-04), 49 49 54 (Lab: E2-08)
>Fax -44-1223- 49 49 19
>Email: alicat at sanger.ac.uk
>User Web page: http://www.sanger.ac.uk/Users/alicat
>
>Research pages:
>http://www.sanger.ac.uk/Projects/L_major/
>http://www.ebi.ac.uk/parasites/leish.html