major ADCL

[Hannah Akuffo]

With regard to the statement "In Phillippe Desjeux's meeting report
("Leishmania/HIV co-infection" -WHO/LEISH/95.35 he cites on page 7: 15
CL-DCL/HIV+ cases from Ethiopia, 10 CL/HIV+ (some must have been anergic
DCL) from Kenya, and one CL/HIV+ from Malawi"  by Dr Robert N Davidson, I
think that before concluding that it is L. major that is being sited as
CL-DCL/HIV+ in Ethiopia, isoenzyme data (or the like) must be available
since L. major is nt common in Ethiopia whilst of course L. aethiopica
which is known to induce DCL is the most common cause of cutaneous
leishmaniasis in this country.

Hannah Akuffo

>I have come across 5 case reportS of DCL due to L major, but imagine there
>are many more, especially if HIV+ cases are considered:
>
>1. The Pediatric Infectious Disease Journal 1995;14:247-8 (HIV+ case)
>2. (HIV NEG)Transactions RSTMH 1996;90:396-7  which in turn cites 2 others:
>        Transactions RSTMH 1990;84:535-6 and
>        Annales de Dermatologie et Venereologie  1993;120:461-3
>3. (HIV NEG) Lancet 1996;348:405
>4. In Phillippe Desjeux's meeting report ("Leishmania/HIV co-infection" -
>WHO/LEISH/95.35 he cites on page 7: 15 CL-DCL/HIV+ cases from Ethiopia, 10
>CL/HIV+ (some must have been anergic DCL) from Kenya, and one CL/HIV+ from
>Malawi.
>
>Robert
>____________________________________________________________________________
>_________
>At 10:30 15/05/97 -0300, you wrote:
>>Does any body know of any published or unpublished cases of anergic diffuse
>cutaneous leishmaniasis (ADCL) caused by Leishmania (Leishmania) major?
>>
>>Many thanks
>>
>>Jeffrey Shaw
>>
>>
>>
>---------------------------------------------------
>Dr Robert N Davidson       email:  r.n.davidson at ic.ac.uk
>Infection and Tropical Medicine, Imperial College School of Medicine
>Northwick Park Hospital, Harrow, HA1  3UJ.
>TEL ++44 181 869 2830     FAX ++44 181 869 2836
>---------------------------------------------------

Hannah Akuffo
Microbiology and Tumor Biology Centre (MTC)
Karolinska Institute
Box 280
S-17 177 Stockholm
Sweden.

Tel: 46 8 728 7236
Fax: 46 8 33 15 47