Leishmaniasis in dogs

[Marco Victor Hermeto]

> From: Reynaldo Dietze <rdietze at npd1.ufes.br>
> To: Multiple recipients of list <leish-l at bdt.org.br>
> Subject: Re: Leishmaniasis in dogs
> Date: Terça-feira, 25 de Junho de 1996 23:15
> 

> 
>                 There is no study using anfotericin B in dogs.  The drug
is
> much more potent than antimonials against leishmaniasis.  The
inconvenient
> will be the IV infusion over a period of 4 hours.

  Using lipossomal
> anfotericin B problably you will have less toxicity with a short
treatment
> time. I will suggest 2 weeks of treatment with a 2mg/kg/day of Amphocil.
 To
> prevent potential side effects such as chills and fever you may consider
> pre-treating the dog with non-steroid antiinflamatory drug.
> _________________________________________
> Reynaldo Dietze, M.D.
> N=FAcleo de Doen=E7as Infecciosas - UFES=20
> Av. Marechal Campos 1468, Maruipe
> CEP: 29040-091
> Vit=F3ria, ES - Brazil
> Tel/Fax: 55-27-3357204

	With humans there is no problems with rapid infusions of anfoB (90
minutes in severe diseases).