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</o:shapelayout></xml><![endif]--></head><body lang=PT-BR link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span style='font-size:14.0pt'>Dear Marco Tulio and Kleber and colleagues<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:14.0pt'> Regarding the work of Soto with miltefosine, 2007, I believe that this has serious methodological errors, such opinions are published on this Article - Mucosal leishmaniasis and miltefosine Tuon FF, Amato VS Clin Infect Dis. 2007 Jun 1, 44 (11) :1525-6; author reply 1526-7. I suggest that a patient would be possibility for this low-dose liposomal amphotericin as 2mg/kg.Por longer time than usual.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:14.0pt'> Best regards<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:14.0pt'> Valdir Amato<o:p></o:p></span></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal><span style='mso-fareast-language:PT-BR'>_____________________________________________<o:p></o:p></span></p><p class=MsoNormal><span style='mso-fareast-language:PT-BR'>Prof. Dr. Valdir Sabbaga Amato<o:p></o:p></span></p><p class=MsoNormal><span style='mso-fareast-language:PT-BR'>Médico Supervisor da Clínica de Moléstias Infecciosas e Parasitárias do HC-FMUSP<o:p></o:p></span></p><p class=MsoNormal><span style='mso-fareast-language:PT-BR'>Responsável pelo Ambulatório de leishmanioses da Clínica de Moléstias Infecciosas e Parasitárias do HC-FMUSP </span><span style='font-size:12.0pt;mso-fareast-language:PT-BR'><o:p></o:p></span></p><p class=MsoNormal><span style='mso-fareast-language:PT-BR'>Orientador de Mestrado e Doutorado<o:p></o:p></span></p><p class=MsoNormal><o:p> </o:p></p></div></body></html>