[Tropmed-l] Tegumentar Leishmaniasis in liver transplant

[Thor Dantas]

Dear colleagues, I have a liver transplant patient for 5 months in use of FK and MMF with a rapid progressive tegumentar leishmaniasis in the face. does anyone have anyexperience in treating this scenario. Furthermore, the patient has diabetes and hypertension and is admitted to the hospital because of intenseasthenia and peripheral neuropathy. Also shows marked elevation of liver enzymes wich is under investigation. a liver biopsy is planned. The main hypotheses are FK toxicity and/or post transplant recurrence of HCV. (rejection seems less likely because the serum level was pretty high).
thanks everybody.
hugs
Thor Dantas