<html><head><style type='text/css'>p { margin: 0; }</style></head><body><div style='font-family: times new roman,new york,times,serif; font-size: 12pt; color: #000000'><br><blockquote style="border-left:2px solid rgb(16, 16, 255);margin-left:5px;padding-left:5px;color:#000;font-weight:normal;font-style:normal;text-decoration:none;font-family:Helvetica,Arial,sans-serif;font-size:12pt;"><div dir="ltr"><div><div dir="ltr"><div><div class="ecxgmail_quote">From: <span dir="ltr"><<a href="mailto:promed@promedmail.org" target="_blank">promed@promedmail.org</a>></span><br>Date: 2015-11-23 17:14 GMT-02:00<br>Subject: PRO/AH/EDR> Leishmaniasis, visceral - East Africa<br>To: <a href="mailto:promed-post@promedmail.org" target="_blank">promed-post@promedmail.org</a>, <a href="mailto:promed-edr-post@promedmail.org" target="_blank">promed-edr-post@promedmail.org</a>, <a href="mailto:promed-ahead-post@promedmail.org" target="_blank">promed-ahead-post@promedmail.org</a><br><br><br><br>
LEISHMANIASIS, VISCERAL - EAST AFRICA<br>
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A ProMED-mail post<br>
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<br>
Date: Fri 20 Nov 2015<br>
Source: AllAfrica, Daily Nation (Nairobi) report [edited]<br>
<<a href="http://allafrica.com/stories/201511200399.html" rel="noreferrer" target="_blank">http://allafrica.com/stories/201511200399.html</a>><br>
<br>
<br>
Visceral leishmaniasis, commonly known as kala-azar, is the most<br>
deadly parasitic disease after malaria. It affects poor people in arid<br>
and semi-arid regions.<br>
<br>
Eastern Africa is the most affected in Africa, with an estimated 29<br>
000 to 56 000 cases every year.<br>
<br>
Like all neglected diseases, kala-azar affects mainly the poorest<br>
populations that have little or no purchasing power. These population<br>
groups are usually overlooked and often do not have access to<br>
life-saving treatments.<br>
<br>
Furthermore, private pharmaceutical companies lack interest in<br>
producing new drugs for patients suffering from neglected diseases<br>
since they cannot recoup their investments in drug development.<br>
<br>
Research for new treatments is, therefore, not prioritised, making<br>
drugs unavailable, inaccessible, and unaffordable.<br>
<br>
In 2003, 4 countries -- Ethiopia, Kenya, Sudan, and Uganda --<br>
partnered to create the Leishmaniasis East Africa Platform (LEAP), the<br>
main mandate of which was to research new treatment options for<br>
kala-azar and support their access.<br>
<br>
[Byline: Monique Wasunna, Asrat Hailu]<br>
<br>
--<br>
Communicated by:<br>
ProMED-mail from HealthMap Alerts<br>
<<a href="mailto:promed@promedmail.org" target="_blank">promed@promedmail.org</a>><br>
<br>
[More information on the Leishmaniasis East Africa Platform (LEAP),<br>
can be found at<br>
<<a href="http://www.dndi.org/strengthening-capacity/leap-platform.html" rel="noreferrer" target="_blank">http://www.dndi.org/strengthening-capacity/leap-platform.html</a>>.<br>
<br>
Leishmaniasis control is primarily based on control of the sandfly<br>
vector and the rodent reservoirs. However, human can also act as<br>
reservoirs and mortality in untreated cases of visceral leishmaniasis<br>
approach 100 percent.<br>
<br>
Visceral leishmaniasis is also an HIV-associated disease and has a<br>
more rapid course in HIV infected persons where treatment also is<br>
difficult even in patients with a high CD4 T cell count. The LEAP<br>
initiative is therefore an important and very welcome initiative to<br>
improve treatment of visceral leishmaniasis in East Africa. - Mod.EP]<br>
<br>
[See Also:<br>
Leishmaniasis, visceral - South Sudan (02):<br>
<a href="http://promedmail.org/post/20151028.3749052" rel="noreferrer" target="_blank">http://promedmail.org/post/20151028.3749052</a><br>
Leishmaniasis, visceral - South Sudan: (JG):<br>
<a href="http://promedmail.org/post/20150118.3100799" rel="noreferrer" target="_blank">http://promedmail.org/post/20150118.3100799</a><br>
2014<br>
----<br>
Leishmaniasis, visceral - South Sudan (03)<br>
<a href="http://promedmail.org/post/20141031.2918104" rel="noreferrer" target="_blank">http://promedmail.org/post/20141031.2918104</a><br>
Leishmaniasis, visceral - South Sudan (02)<br>
<a href="http://promedmail.org/post/20141006.2836861" rel="noreferrer" target="_blank">http://promedmail.org/post/20141006.2836861</a><br>
Leishmaniasis, visceral - South Sudan: (JG)<br>
<a href="http://promedmail.org/post/20140909.2760146" rel="noreferrer" target="_blank">http://promedmail.org/post/20140909.2760146</a><br>
2012<br>
----<br>
Leishmaniasis, visceral - South Sudan (03): (JG)<br>
<a href="http://promedmail.org/post/20121015.1343672" rel="noreferrer" target="_blank">http://promedmail.org/post/20121015.1343672</a><br>
Leishmaniasis, visceral - South Sudan (02): (UY)<br>
<a href="http://promedmail.org/post/20120916.1295988" rel="noreferrer" target="_blank">http://promedmail.org/post/20120916.1295988</a><br>
Leishmaniasis, visceral - South Sudan<br>
<a href="http://promedmail.org/post/20120421.1109078" rel="noreferrer" target="_blank">http://promedmail.org/post/20120421.1109078</a><br>
2011<br>
----<br>
Leishmaniasis, visceral - South Sudan (JO, UN)<br>
<a href="http://promedmail.org/post/20111111.3346" rel="noreferrer" target="_blank">http://promedmail.org/post/20111111.3346</a><br>
Leishmaniasis, visceral - Sudan: (southern)<br>
<a href="http://promedmail.org/post/20110313.0810" rel="noreferrer" target="_blank">http://promedmail.org/post/20110313.0810</a><br>
2009<br>
----<br>
Leishmaniasis - Sudan: (southern)<br>
<a href="http://promedmail.org/post/20091107.3851" rel="noreferrer" target="_blank">http://promedmail.org/post/20091107.3851</a><br>
2008<br>
----<br>
Leishmaniasis, visceral - Kenya (02): (NE)<br>
<a href="http://promedmail.org/post/20080806.2416" rel="noreferrer" target="_blank">http://promedmail.org/post/20080806.2416</a><br>
Leishmaniasis, visceral - Kenya: (NE)<br>
<a href="http://promedmail.org/post/20080613.1871" rel="noreferrer" target="_blank">http://promedmail.org/post/20080613.1871</a><br>
2006<br>
----<br>
Leishmaniasis, visceral - Kenya (Eastern) (02): comment<br>
<a href="http://promedmail.org/post/20060723.2030" rel="noreferrer" target="_blank">http://promedmail.org/post/20060723.2030</a><br>
Leishmaniasis, visceral - Kenya (Eastern)<br>
<a href="http://promedmail.org/post/20060721.2007" rel="noreferrer" target="_blank">http://promedmail.org/post/20060721.2007</a><br>
2005<br>
----<br>
Leishmaniasis, visceral - Ethiopia<br>
<a href="http://promedmail.org/post/20050705.1903" rel="noreferrer" target="_blank">http://promedmail.org/post/20050705.1903</a><br>
2000<br>
----<br>
Leishmaniasis, visceral - Kenya (Wajir) (06)<br>
<a href="http://promedmail.org/post/20000828.1439" rel="noreferrer" target="_blank">http://promedmail.org/post/20000828.1439</a><br>
Leishmaniasis, visceral - Kenya (Wajir) (05)<br>
<a href="http://promedmail.org/post/20000825.1421" rel="noreferrer" target="_blank">http://promedmail.org/post/20000825.1421</a><br>
Leishmaniasis, visceral - Kenya (Wajir) (04)<br>
<a href="http://promedmail.org/post/20000714.1165" rel="noreferrer" target="_blank">http://promedmail.org/post/20000714.1165</a><br>
Leishmaniasis, visceral - Kenya (Wajir) (03)<br>
<a href="http://promedmail.org/post/20000705.1113" rel="noreferrer" target="_blank">http://promedmail.org/post/20000705.1113</a><br>
Leishmaniasis, visceral - Kenya (Wajir) (02)<br>
<a href="http://promedmail.org/post/20000626.1053" rel="noreferrer" target="_blank">http://promedmail.org/post/20000626.1053</a><br>
Leishmaniasis, visceral - Kenya (Wajir)<br>
<a href="http://promedmail.org/post/20000625.1048" rel="noreferrer" target="_blank">http://promedmail.org/post/20000625.1048</a>]<br>
.................................................sb/ep/mj/lm<br>
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