<html><head><style type='text/css'>p { margin: 0; }</style></head><body><div style='font-family: times new roman,new york,times,serif; font-size: 12pt; color: #000000'>De: <<a href="mailto:promed@promedmail.org" target="_blank">promed@promedmail.org</a>><br><blockquote style="border-left:2px solid rgb(16, 16, 255);margin-left:5px;padding-left:5px;color:#000;font-weight:normal;font-style:normal;text-decoration:none;font-family:Helvetica,Arial,sans-serif;font-size:12pt;"><div dir="ltr"><div>Data: sábado, 24 de outubro de 2015<br>Assunto: PRO/AH/EDR> Leishmaniasis, visceral - Brazil: (MS)<br>Para: <a href="mailto:promed-post@promedmail.org" target="_blank">promed-post@promedmail.org</a>, <a href="mailto:promed-edr-post@promedmail.org" target="_blank">promed-edr-post@promedmail.org</a>, <a href="mailto:promed-ahead-post@promedmail.org" target="_blank">promed-ahead-post@promedmail.org</a><br><br><br><br>
LEISHMANIASIS, VISCERAL - BRAZIL: (MATO GROSSO DO SUL)<br>
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A ProMED-mail post<br>
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<br>
Date: Thu 22 Oct 2015<br>
Source: Campo Grande News [in Portuguese, trans. Corr.SB, edited]<br>
<<a href="http://www.campograndenews.com.br/cidades/com-102-casos-confirmados-morre-mais-um-paciente-com-leishmaniose" target="_blank">http://www.campograndenews.com.br/cidades/com-102-casos-confirmados-morre-mais-um-paciente-com-leishmaniose</a>><br>
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Increase in cases of visceral leishmaniasis, Campo Grande<br>
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>From January [2015] until [20 Oct 2015], there were 181 confirmed<br>
cases and 8 deaths. Deaths were in Campo Grande (2), Corumba (4),<br>
Jardim (1), and Ladario (1) [Mato Grosso do Sul state].<br>
<br>
In 2014, there were 181 cases with 11 deaths recorded in Aquidauana<br>
(1), Campo Grande (6), Corumba (3) and Sao Gabriel do Oeste (1) [Mato<br>
Grosso do Sul state].<br>
<br>
In July [2015], a study showed that Campo Grande, with 55 cases, was<br>
among the 4 cities in the country with the highest number of cases of<br>
leishmaniasis in humans. The number is considered worrisome and was<br>
reported in the PhD animal science lecture of Francisco Anilton Araujo<br>
held at UFMS (Federal University of Mato Grosso do Sul) during the<br>
National Week for Combating Visceral Leishmaniasis.<br>
<br>
[Byline: Viviane Oliveira]<br>
<br>
--<br>
Communicated by:<br>
ProMED-mail<br>
<<a target="_blank">promed@promedmail.org</a>><br>
<br>
[The study mentioned is Druzian AF et al. (Risk Factors for Death from<br>
Visceral Leishmaniasis in an Urban Area of Brazil. PLoS Negl Trop Dis.<br>
2015 Aug 14;9(8):e0003982). The main findings were that 36.6 percent<br>
of the patients were co-infected with HIV/AIDS, and the mortality rate<br>
was 21.6 percent. In a multivariate analysis, the risk factors<br>
associated with death were secondary bacterial infection (42.86,<br>
5.05-363.85), relapse (12.17, 2.06-71.99), edema (7.74, 1.33-45.05)<br>
and HIV/AIDS co-infection (7.33, 1.22-43.98).<br>
<br>
It is well known that treatment of visceral leishmaniasis in<br>
HIV-infected patients is very difficult, and some studies suggest that<br>
it cannot be cured, so that lifelong treatment is necessary (Bourgeois<br>
N et al. Active chronic visceral leishmaniasis in HIV-1-infected<br>
patients demonstrated by biological and clinical long-term follow-up<br>
of 10 patients. HIV Med. 2010;11:670-3).<br>
<br>
Thus, data on the number of patients with visceral leishmaniasis can<br>
only be interpreted if the proportion HIV positives are known. -<br>
Mod.EP<br>
<br>
A HealthMap/ProMED-mail map can be accessed at:<br>
<<a href="http://healthmap.org/promed/p/6632" target="_blank">http://healthmap.org/promed/p/6632</a>>.]<br>
<br>
[See Also:<br>
2014<br>
----<br>
Leishmaniasis - Brazil: (MS): 20140118.2182680<br>
2012<br>
----<br>
Leishmaniasis, canine - Brazil: (MG) 20121111.1404680<br>
2010<br>
----<br>
Leishmaniasis, human - Brazil (MG) 20100211.0487<br>
2009<br>
----<br>
Leishmaniasis, visceral - Brazil: (MT), human, canine 20090123.0290<br>
2008<br>
----<br>
Leishmaniasis, visceral - Brazil (03): (DF), human, canine<br>
20081130.3766<br>
Leishmaniasis, visceral - Brazil (02): (Mato Grosso), background<br>
20080127.0338<br>
Leishmaniasis, visceral - Brazil: (Mato Grosso) 20080125.0314<br>
2007<br>
----<br>
Leishmaniasis - Brazil (RJ) 20070508.1477<br>
2003<br>
----<br>
Leishmaniasis - Brazil (Sao Paulo) 20030114.0114<br>
2002<br>
----<br>
Leishmaniasis - Brazil (Mato Grosso do Sul) (02) 20020524.4314<br>
Leishmaniasis - Brazil (Mato Grosso do Sul): RFI 20020520.4284<br>
1999<br>
----<br>
Leishmaniasis, visceral, fatal - Brazil (Sao Paulo) (02)<br>
19990722.1235<br>
Leishmaniasis, visceral, fatal - Brazil (Sao Paulo) 19990616.1023<br>
1998<br>
----<br>
Leishmaniasis - Brazil: Background 19981114.2203<br>
Leishmaniasis, visceral, dogs - Brazil (Sao Paulo) 19981110.2175]<br>
.................................................sb/ep/je/ml<br>
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