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<p>Dear colleagues,<br>
<br>
Thank yo for this interesting information.<br>
However no attachment.<br>
<br>
I would very much appreciate if some one of you could send me the attachment in which the article is shown.<br>
<br>
Thanks in advance,<br>
with kind regards, </p>
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<p> </p>
<p>Pieter van Thiel</p>
<p> </p>
<p><strong>P.P.A.M. van Thiel, MD PhD<br>
</strong></p>
<p><font size="1"><strong>Internist, infectious disease physician,<br>
Former consultant to the Surgeon General NL Armed Forces<br>
...................................................................................................................................................</strong></font></p>
<p><font size="1"><strong>Division of Infectious Diseases, Center for Tropical and Travel Medicine</strong></font></p>
<p><font size="1"><strong>Academic Medical Center, University of Amsterdam<br>
</strong>Meibergdreef 9<br>
1105 AZ AMSTERDAM, THE NETHERLANDS<br>
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<p><font size="1"><strong>E-mail:</strong> </font><a tabindex="0" href="mailto:p.p.vanthiel@amc.uva.nl" target=""><font size="1">p.p.vanthiel@amc.uva.nl</font></a><br>
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<p><br>
________________________________________<br>
Van: leish-l-bounces@lineu.icb.usp.br [leish-l-bounces@lineu.icb.usp.br] namens josé carlos [jcribeiro.pi@ig.com.br]<br>
Verzonden: maandag 2 december 2013 13:57<br>
Aan: leish-l@lineu.icb.usp.br; Michal Baniyash; Carlos Costa<br>
Onderwerp: Re: [Leish-l] etanercept and kala-azar<br>
<br>
Em 28/11/2013 15:50, josé carlos escreveu:<br>
> Good afternoon friends,<br>
><br>
> I came across the attached article and was wondering if the use of<br>
> etanercept at the appropriate time would represent an important<br>
> advance in the treatment of kala-azar to allow the body does not come<br>
> into immunosuppression and destroy the parasite. I did a quick search<br>
> on pubmed and found no article that answered my question, MDSC are<br>
> elevated in leishmaniasis? etanercept at the appropriate time heals<br>
> the patient with kala-azar?<br>
><br>
> best regards,<br>
><br>
> José Carlos<br>
> Lableish- IDTNP<br>
> Teresina - PI - Brazil<br>
dear friends,<br>
<br>
I received an email from michal dr baniyash (author of the article<br>
attached in previous mail) and everything indicates that MDSC are<br>
elevated in visceral leishmaniasis. after receiving his mail had a<br>
insigth that TNF-alpha increases and then to be deposited in the<br>
membranes of macrophages in the blood decreases, so if we use etanercept<br>
at the right time when the TNF-alpha is not yet deposited in the<br>
membranes can decrease immunosuppression. or will the TNF-alpha is not<br>
deposited, but is expressed by the macrophage itself inside out?<br>
<br>
regards,<br>
<br>
josé carlos<br>
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--<br>
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This email was sent by icb.usp.br</p>
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