<html><body><div style="color:#000; background-color:#fff; font-family:times new roman, new york, times, serif;font-size:18pt"><div><span>Dear All,</span></div><div style="color: rgb(0, 0, 0); font-size: 24px; font-family: 'times new roman', 'new york', times, serif; background-color: transparent; font-style: normal;"><span><br></span></div><div style="color: rgb(0, 0, 0); font-size: 24px; font-family: 'times new roman', 'new york', times, serif; background-color: transparent; font-style: normal;"><span>I think removal of spleen will not cure patients because high parasitemia is also present in liver along with lymph nodes. In any circumstance we can not remove liver which will hamper such study. </span></div><div style="color: rgb(0, 0, 0); font-size: 24px; font-family: 'times new roman', 'new york', times, serif; background-color: transparent; font-style: normal;"><span><br></span></div><div style="color: rgb(0, 0, 0); font-size: 24px;
font-family: 'times new roman', 'new york', times, serif; background-color: transparent; font-style: normal;"><span>Thanks </span></div><div></div><div> </div><div>Sandeep Verma,<br>Senior Research Fellow(SRF),<br>Molecular Biology Lab,<br>National Institute of Pathology (ICMR)<br>Safdarjung Hospital Campus<br>New Delhi 110029<br>Mobile no. +91-9717136244</div><div><br></div> <div style="font-family: 'times new roman', 'new york', times, serif; font-size: 18pt;"> <div style="font-family: 'times new roman', 'new york', times, serif; font-size: 12pt;"> <div dir="ltr"> <hr size="1"> <font size="2" face="Arial"> <b><span style="font-weight:bold;">From:</span></b> Dr Omar Hamarsheh <ohamarsheh@gmail.com><br> <b><span style="font-weight: bold;">To:</span></b> 'Carlos Costa' <chncosta@gmail.com>; 'Leish-L' <Leish-l@lineu.icb.usp.br> <br> <b><span style="font-weight: bold;">Sent:</span></b> Tuesday, 27 August 2013 1:57 PM<br>
<b><span style="font-weight: bold;">Subject:</span></b> Re: [Leish-l] spleen<br> </font> </div> <div class="y_msg_container"><br><div id="yiv2265094017"><style><!--
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--></style><div><div class="yiv2265094017WordSection1"><div class="yiv2265094017MsoNormal"><span style="font-size: 11pt; font-family: Calibri, sans-serif; color: rgb(31, 73, 125);">Dear All,</span></div><div class="yiv2265094017MsoNormal"><span style="font-size: 11pt; font-family: Calibri, sans-serif; color: rgb(31, 73, 125);">I am not an immunologist but I have an opinion that I would like to share; splenectomy cures patients with Visceral Leishmaniasis. </span></div><div class="yiv2265094017MsoNormal"><span style="font-size: 11pt; font-family: Calibri, sans-serif; color: rgb(31, 73, 125);">large masses of Leishmania in case of visceral Leishmaniasis is existed in reticuloendothelial system including spleen. Removal of spleen will remove huge masses of the parasite infected cells. In cases of serious splenomegaly and cytopenia, spelenectomy become a good option.</span></div><div class="yiv2265094017MsoNormal"><span style="font-size: 11pt;
font-family: Calibri, sans-serif; color: rgb(31, 73, 125);"> </span></div><div class="yiv2265094017MsoNormal"><span style="font-size: 11pt; font-family: Calibri, sans-serif; color: rgb(31, 73, 125);">All the best,</span></div><div class="yiv2265094017MsoNormal"><span style="font-size: 11pt; font-family: Calibri, sans-serif; color: rgb(31, 73, 125);">omar</span></div><div class="yiv2265094017MsoNormal"><span style="font-size: 11pt; font-family: Calibri, sans-serif; color: rgb(31, 73, 125);"> </span></div><div class="yiv2265094017MsoNormal"><b><span style="color:black;">-------------------------------------</span></b></div><div class="yiv2265094017MsoNormal"><b><span style="color:black;">Omar Hamarsheh, MSc., PhD</span></b></div><div class="yiv2265094017MsoNormal"><b><span style="color:black;">Al-Quds University</span></b></div><div class="yiv2265094017MsoNormal"><b><span style="color:black;">Department of Biological
Sciences</span></b></div><div class="yiv2265094017MsoNormal"><b><span style="color:black;">P.O.Box 51000</span></b></div><div class="yiv2265094017MsoNormal"><b><span style="color:black;">Jerusalem</span></b></div><div class="yiv2265094017MsoNormal"><b><span style="color:black;">PALESTINE</span></b></div><div class="yiv2265094017MsoNormal"><b><span style="color:black;"> </span></b></div><div class="yiv2265094017MsoNormal"><b><span style="color:black;">Tel: 00970-599197097</span></b></div><div class="yiv2265094017MsoNormal"><b><span style="color:black;">Fax: 00970-22796960</span></b></div><div class="yiv2265094017MsoNormal"><b><span style="color:black;"> </span></b></div><div class="yiv2265094017MsoNormal"><b><span style="color:black;">Email: <a rel="nofollow" ymailto="mailto:ohamarsheh@gmail.com" target="_blank" href=""><span style="color:blue;">ohamarsheh@gmail.com</span></a></span></b></div><div class="yiv2265094017MsoNormal"><b><span
style="color:black;"> <a rel="nofollow" target="_blank" href=""><span style="color:blue;">mail.alquds.edu/~f3706/</span></a></span></b></div><div class="yiv2265094017MsoNormal"><span style="font-size: 11pt; font-family: Calibri, sans-serif; color: rgb(31, 73, 125);"> </span></div><div style="border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt 0in 0in 0in;"><div class="yiv2265094017MsoNormal"><b><span style="font-size: 10pt; font-family: Tahoma, sans-serif;">From:</span></b><span style="font-size: 10pt; font-family: Tahoma, sans-serif;"> leish-l-bounces@lineu.icb.usp.br [mailto:leish-l-bounces@lineu.icb.usp.br] <b>On Behalf Of </b>Carlos Costa<br><b>Sent:</b> Wednesday, August 21, 2013 3:53 PM<br><b>To:</b> Leish-L<br><b>Subject:</b> [Leish-l] spleen</span></div></div><div class="yiv2265094017MsoNormal"> </div><div><div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana,
sans-serif; color: black;">Dear leishimmunologists,</span></div></div><div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif; color: black;"> </span></div></div><div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif; color: black;">Do you have any guess on why splenectomy cures kala-azar? Would it be the absence of spleen-derived IL-10?</span></div></div><div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif; color: black;"> </span></div></div><div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif; color: black;">All my best,</span></div></div><div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif; color: black;"> </span></div></div><div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif; color: black;">Carlos.</span></div></div><div><div
class="yiv2265094017MsoNormal"> </div></div><div class="yiv2265094017MsoNormal">-- </div><div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif;">Carlos H. N. Costa, MD, DSc.</span></div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif;">Coordenador</span></div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif;">Laboratório de Leishmanioses - LabLeish</span></div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif;">Universidade Federal do Piauí</span></div><div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif;">Instituto de Doenças Tropicais Natan Portella</span></div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif;">Rua Artur de Vasconcelos 151-Sul</span></div><div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana,
sans-serif;">64001-450 Teresina-PI</span></div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif;">Brazil</span></div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif;">Telephones: +55 86 3222-4377 (W), </span></div><div class="yiv2265094017MsoNormal" align="center" style="text-align:center;"><span style="font-family: Verdana, sans-serif;">+55 86 3221-3062 (W), </span></div><div class="yiv2265094017MsoNormal" align="center" style="text-align:center;"><span style="font-family: Verdana, sans-serif;">+55 86 3237-1075 (R). </span></div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif;"> </span></div><div class="yiv2265094017MsoNormal"><span style="font-family: Verdana, sans-serif;"> </span></div><div class="yiv2265094017MsoNormal"><span style="font-size: 10pt; font-family: Verdana, sans-serif;">Aviso: As informações contidas nesta
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