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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>I think you getting rid of a major reservoir of macrophages which harbor the parasites<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Abhay R Satoskar MBBS, MD, PhD<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Professor & Vice Chair for Research<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Departments of Pathology and Microbiology<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Wexner Medical Center <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>The Ohio State University<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>129 Hamilton Hall<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>1645 Neil Avenue<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Columbus, Ohio 43210<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Tel:614-366-3417<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><div style='border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt 0in 0in 0in'><p class=MsoNormal><b><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>From:</span></b><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'> leish-l-bounces@lineu.icb.usp.br [mailto:leish-l-bounces@lineu.icb.usp.br] <b>On Behalf Of </b>Carlos Costa<br><b>Sent:</b> Wednesday, August 21, 2013 8:53 AM<br><b>To:</b> Leish-L<br><b>Subject:</b> [Leish-l] spleen<o:p></o:p></span></p></div><p class=MsoNormal><o:p> </o:p></p><div><div><p class=MsoNormal><span style='font-family:"Verdana","sans-serif";color:black'>Dear leishimmunologists,<o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-family:"Verdana","sans-serif";color:black'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-family:"Verdana","sans-serif";color:black'>Do you have any guess on why splenectomy cures kala-azar? Would it be the absence of spleen-derived IL-10?<o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-family:"Verdana","sans-serif";color:black'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-family:"Verdana","sans-serif";color:black'>All my best,<o:p></o:p></span></p></div><div><p class=MsoNormal><span style='font-family:"Verdana","sans-serif";color:black'><o:p> </o:p></span></p></div><div><p class=MsoNormal><span style='font-family:"Verdana","sans-serif";color:black'>Carlos.<o:p></o:p></span></p></div><div><p class=MsoNormal><o:p> </o:p></p></div><p class=MsoNormal>-- <o:p></o:p></p><div><p class=MsoNormal><span style='font-family:"Verdana","sans-serif"'>Carlos H. N. Costa, MD, DSc.</span><o:p></o:p></p><p class=MsoNormal><span style='font-family:"Verdana","sans-serif"'>Coordenador</span><o:p></o:p></p><p class=MsoNormal><span style='font-family:"Verdana","sans-serif"'>Laboratório de Leishmanioses - LabLeish</span><o:p></o:p></p><p class=MsoNormal><span style='font-family:"Verdana","sans-serif"'>Universidade Federal do Piauí</span><o:p></o:p></p><div><p class=MsoNormal><span style='font-family:"Verdana","sans-serif"'>Instituto de Doenças Tropicais Natan Portella</span><o:p></o:p></p><p class=MsoNormal><span style='font-family:"Verdana","sans-serif"'>Rua Artur de Vasconcelos 151-Sul</span><o:p></o:p></p><div><p class=MsoNormal><span style='font-family:"Verdana","sans-serif"'>64001-450 Teresina-PI</span><o:p></o:p></p><p class=MsoNormal><span style='font-family:"Verdana","sans-serif"'>Brazil<o:p></o:p></span></p><p class=MsoNormal><span style='font-family:"Verdana","sans-serif"'>Telephones: +55 86 3222-4377 (W), <o:p></o:p></span></p><p class=MsoNormal align=center style='text-align:center'><span style='font-family:"Verdana","sans-serif"'>+55 86 3221-3062 (W), <o:p></o:p></span></p><p class=MsoNormal align=center style='text-align:center'><span style='font-family:"Verdana","sans-serif"'>+55 86 3237-1075 (R). <o:p></o:p></span></p><p class=MsoNormal><span style='font-family:"Verdana","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-family:"Verdana","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'>Aviso: As informações contidas nesta mensagem são CONFIDENCIAIS, protegidas pelo sigilo legal, por direitos autorais e destinadas exclusivamente à pessoa ou organização para a qual a mensagem foi destinada.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'>Warning: This message is meant only for the intended recipient of the transmission. It is forbidden any unauthorized use, alteration, reproduction and distribution. If you are not the correct recipient, please notify us immediately by return e-mail and delete this message from your system.<o:p></o:p></span></p></div></div></div></div><p class=MsoNormal><br><br>--<br><i>This email was sent by icb.usp.br </i> <o:p></o:p></p></div></body></html>