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<p class="MsoNormal"><span lang="ES" style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">María-Gloria :<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="ES" style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">¿Quieres empezar una discusión sobre el desarrollo de las drogas?
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">Then I’d have my own list<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">But first and foremost: it is becoming VERY difficult today to convince decision makers to fund anti-leishmania drug R&D. So, one would have to start from there:
are new drugs needed? and which drugs? and we won’t have to preach to the converted (ourselves) but rather to the pagans. Shall we not start from there?<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">Meanwhile: !Felices pasquas!
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D">Piero<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
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<p class="MsoNormal"><b><span lang="EN-US" style="font-size:10.0pt;font-family:"Tahoma","sans-serif"">From:</span></b><span lang="EN-US" style="font-size:10.0pt;font-family:"Tahoma","sans-serif""> leish-l-bounces@lineu.icb.usp.br [mailto:leish-l-bounces@lineu.icb.usp.br]
<b>On Behalf Of </b>Basanez, Maria-Gloria<br>
<b>Sent:</b> 11 March 2013 16:24<br>
<b>To:</b> 'Carlos Costa'; 'Leish-L'<br>
<b>Subject:</b> Re: [Leish-l] hot spots<o:p></o:p></span></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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<p><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:black">Not sure it's most polemic, but if you are thinking of collating and discussing a research & development agenda for leishmaniasis, I would like to add the updating
of mathematical transmission models, including multi-host systems, and the linking of such population dynamic models (rather than static ones) with analyses of economic evaluation for the cost-effectiveness analyses of interventions.<o:p></o:p></span></p>
<p><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:black"> <o:p></o:p></span></p>
<p><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:black">Best wishes to all,<o:p></o:p></span></p>
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<p><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:black"> <o:p></o:p></span></p>
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<p class="MsoNormal"><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Arial","sans-serif";color:gray">Professor María-Gloria Basáñez MSc PhD FRES</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:gray">
</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Arial","sans-serif";color:gray">Chair in Neglected Tropical Diseases</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Arial","sans-serif";color:gray">School of Public Health</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:gray"> <br>
</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Arial","sans-serif";color:gray">Department of Infectious Disease Epidemiology</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:gray">
<br>
</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Arial","sans-serif";color:gray">Faculty of Medicine (St Mary's campus)</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:gray">
<br>
</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Arial","sans-serif";color:gray">Imperial College London</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:gray">
<br>
</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Arial","sans-serif";color:gray">Norfolk Place, London W2 1PG, UK</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:gray">
</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Arial","sans-serif";color:gray">Tel: + 44 0(20) 75943295</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:gray">
<br>
</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Arial","sans-serif";color:gray">Fax: +44 0(20) 74023927</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:gray">
<br>
</span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Arial","sans-serif";color:gray">E-mail:
<a href="mailto:m.basanez@imperial.ac.uk">m.basanez@imperial.ac.uk</a> </span><span lang="ES-TRAD" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span lang="ES-TRAD" style="color:black"><o:p> </o:p></span></p>
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<div class="MsoNormal" align="center" style="text-align:center"><span lang="ES" style="color:black">
<hr size="2" width="100%" align="center">
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<p class="MsoNormal"><b><span lang="ES" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:black">De:</span></b><span lang="ES" style="font-size:10.0pt;font-family:"Tahoma","sans-serif";color:black">
<a href="mailto:leish-l-bounces@lineu.icb.usp.br">leish-l-bounces@lineu.icb.usp.br</a> [<a href="mailto:leish-l-bounces@lineu.icb.usp.br">mailto:leish-l-bounces@lineu.icb.usp.br</a>]
<b>En nombre de </b>Carlos Costa<br>
<b>Enviado el:</b> jueves, 07 de febrero de 2013 8:39<br>
<b>Para:</b> Leish-L<br>
<b>Asunto:</b> [Leish-l] hot spots</span><span lang="ES-TRAD" style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span lang="ES-TRAD" style="color:black"> <o:p></o:p></span></p>
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<p class="MsoNormal"><span lang="ES-TRAD" style="font-family:"Verdana","sans-serif";color:black">What are the most polemic issues in leishmaniasis?<br clear="all">
</span><span lang="ES-TRAD" style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span lang="ES-TRAD" style="color:black"> <o:p></o:p></span></p>
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<p class="MsoNormal"><span lang="ES-TRAD" style="color:black">-- <o:p></o:p></span></p>
<p class="MsoNormal"><span lang="ES-TRAD" style="font-family:"Verdana","sans-serif";color:black">Carlos H. N. Costa, MD, DSc.</span><span lang="ES-TRAD" style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="ES-TRAD" style="font-family:"Verdana","sans-serif";color:black">Sociedade Brasileira de Medicina Tropical </span><span lang="ES-TRAD" style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="ES-TRAD" style="font-family:"Verdana","sans-serif";color:black">(Brazilian Society of Tropical Medicine)</span><span lang="ES-TRAD" style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="ES-TRAD" style="font-family:"Verdana","sans-serif";color:black">President</span><span lang="ES-TRAD" style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="ES-TRAD" style="color:black"> <o:p></o:p></span></p>
<p class="MsoNormal"><span lang="ES-TRAD" style="font-family:"Verdana","sans-serif";color:black">Universidade Federal do Piauí</span><span lang="ES-TRAD" style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span lang="ES-TRAD" style="font-family:"Verdana","sans-serif";color:black">Instituto de Doenças Tropicais Natan Portella</span><span lang="ES-TRAD" style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="ES-TRAD" style="font-family:"Verdana","sans-serif";color:black">Rua Artur de Vasconcelos 151-Sul</span><span lang="ES-TRAD" style="color:black"><o:p></o:p></span></p>
<div>
<p class="MsoNormal"><span lang="ES-TRAD" style="font-family:"Verdana","sans-serif";color:black">64001-450 Teresina-PI</span><span lang="ES-TRAD" style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="ES-TRAD" style="font-family:"Verdana","sans-serif";color:black">Brazil</span><span lang="ES-TRAD" style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="ES-TRAD" style="font-family:"Verdana","sans-serif";color:black">Telephones: +55 86 3222-4377 (W), </span><span lang="ES-TRAD" style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span lang="ES-TRAD" style="font-family:"Verdana","sans-serif";color:black">+55 86 3221-3062 (W), </span><span lang="ES-TRAD" style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span lang="ES-TRAD" style="font-family:"Verdana","sans-serif";color:black">+55 86 3237-1075 (R). </span><span lang="ES-TRAD" style="color:black"><o:p></o:p></span></p>
<p class="MsoNormal"><span lang="ES-TRAD" style="color:black"> <o:p></o:p></span></p>
<p class="MsoNormal"><span lang="ES-TRAD" style="color:black"> <o:p></o:p></span></p>
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