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<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>Ali is right.<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>KP<o:p></o:p></span></font></p>
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10.0pt;font-family:Arial;color:navy'><o:p> </o:p></span></font></p>
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<p class=MsoNormal><b><font size=2 face=Tahoma><span style='font-size:10.0pt;
font-family:Tahoma;font-weight:bold'>From:</span></font></b><font size=2
face=Tahoma><span style='font-size:10.0pt;font-family:Tahoma'>
leish-l-bounces@lineu.icb.usp.br [mailto:leish-l-bounces@lineu.icb.usp.br] <b><span
style='font-weight:bold'>On Behalf Of </span></b>Ali Khamesipour<br>
<b><span style='font-weight:bold'>Sent:</span></b> Friday, January 27, 2012
10:28 PM<br>
<b><span style='font-weight:bold'>To:</span></b> Kelly Harkins; Christopher
Peacock<br>
<b><span style='font-weight:bold'>Cc:</span></b> leish-l@lineu.icb.usp.br<br>
<b><span style='font-weight:bold'>Subject:</span></b> Re: [Leish-l]
paleopathology and leishmaniasis</span></font><o:p></o:p></p>
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<p class=MsoNormal><font size=2 face=Arial><span style='font-size:10.0pt;
font-family:Arial'>Dear Kelly,<o:p></o:p></span></font></p>
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<p class=MsoNormal><font size=2 face=Arial><span style='font-size:10.0pt;
font-family:Arial'>In our region cutaneous form of leishmaniasis remains in
dermis, epidermis, subdermal soft tissues and lymph nodes, and in case of
systemic form also as far as I know skeleton is not attacked, I
agree with Christopher but the in Inca pottery or in Pyramid might
be leishmaniasis or possibly leprosy.<o:p></o:p></span></font></p>
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<p class=MsoNormal><font size=2 face=Arial><span style='font-size:10.0pt;
font-family:Arial'>All the best Ali </span></span></font><o:p></o:p></p>
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style='font-size:12.0pt'> <o:p></o:p></span></font></p>
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style='font-size:12.0pt'><br>
--- On <b><span style='font-weight:bold'>Fri, 1/27/12, Christopher Peacock <i><span
style='font-style:italic'><christopher.peacock@uwa.edu.au></span></i></span></b>
wrote:<o:p></o:p></span></font></p>
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face="Times New Roman"><span style='font-size:12.0pt'><br>
From: Christopher Peacock <christopher.peacock@uwa.edu.au><br>
Subject: Re: [Leish-l] paleopathology and leishmaniasis<br>
To: "Kelly Harkins" <kelly.harkins@gmail.com><br>
Cc: "leish-l@lineu.icb.usp.br" <leish-l@lineu.icb.usp.br><br>
Date: Friday, January 27, 2012, 8:18 AM<o:p></o:p></span></font></p>
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<p class=MsoNormal><font size=3 face="Times New Roman"><span
style='font-size:12.0pt'>Hi Kelly,<br>
I would imagine that it will be very difficult to identify leishmaniasis in
archeological remains. Leishmaniasis predates man in the <st1:country-region
w:st="on"><st1:place w:st="on">Americas</st1:place></st1:country-region> by a
long margin. Visceral disease was only introduced after 16 th century with
the slave trade, cutaneous only causes damage to the dermis epidermis and
subdermal soft tissue. That leaves mucosal caused by the Viannia species but
although that dest<st1:PersonName w:st="on">roy</st1:PersonName>s the naso
pharyngeal region I thought it was mainly cartilaginous and soft tissue
damage. I recall pictures if Inca pottery portraying ML so it was certainly
present.<br>
<br>
Sent from my iPad<br>
<br>
On 27/01/2012, at 19:52, "Kelly Harkins" <<a
href="http://us.mc1612.mail.yahoo.com/mc/compose?to=kelly.harkins@gmail.com"
ymailto="mailto:kelly.harkins@gmail.com">kelly.harkins@gmail.com</a>>
wrote:<br>
<br>
> Hello all,<br>
> <br>
> I'm new to the mailing list and new to the leishmanisis community. I<br>
> am a doctoral student in bioarchaeology at <st1:place w:st="on"><st1:PlaceName
w:st="on">Arizona</st1:PlaceName> <st1:PlaceType w:st="on">State</st1:PlaceType>
<st1:PlaceType w:st="on">University</st1:PlaceType></st1:place>,<br>
> focusing on the evolutionary history of leishmaniasis, specifically in<br>
> the <st1:place w:st="on">New World</st1:place>, with modern
(next-generation sequencing) and ancient<br>
> molecular approaches, as well as archaeological approach. I am also<br>
> interested in the differential human immune response, as it seems<br>
> there is no absolute predictable association between species of<br>
> Leishmania and clinical outcome? As you all know, this parasite is<br>
> fascinating!<br>
> <br>
> I have located some potential cases of leishmaniasis in human remains<br>
> that have affected the underlying bone and facial structure. But in<br>
> paleopathology, there is no standard differential diagnosis for<br>
> determining these cases, and without the clinical background and<br>
> without x-rays, I cannot fully understand the<br>
> timing/nature/pattern/variability of the potential bone destruction<br>
> that can be associated with chronic lesions, especially of the<br>
> mucucutaneous type (more likely to show up in archaeological remains).<br>
> I want other archaeologists to be able to add leishmaniasis to the<br>
> list of conditions they consider when viewing skeletons in<br>
> prehistorically endemic areas, but in my opinion, it's not quite there<br>
> yet...<br>
> <br>
> So my question to the group is whether anyone knows of potential<br>
> resources I could access to develop a better differential diagnosis in<br>
> skeletal remains, for example, research groups with collections of<br>
> radiographs from patients? clinics in endemic areas that would allow<br>
> me to visit? Any ideas are appreciated.<br>
> <br>
> Thank you for your time,<br>
> <br>
> Kelly Harkins<br>
> <br>
> -- <br>
> Kelly M. Harkins, PhD student<br>
> Center for Bioarchaeological Research<br>
> <st1:place w:st="on"><st1:PlaceType w:st="on">School</st1:PlaceType> of <st1:PlaceName
w:st="on">Human</st1:PlaceName></st1:place> Evolution and Social Change<br>
> <st1:place w:st="on"><st1:PlaceName w:st="on">Arizona</st1:PlaceName> <st1:PlaceType
w:st="on">State</st1:PlaceType> <st1:PlaceType w:st="on">University</st1:PlaceType></st1:place><br>
> <st1:place w:st="on"><st1:City w:st="on">Tempe</st1:City>, <st1:State
w:st="on">AZ</st1:State>, <st1:PostalCode w:st="on">85281</st1:PostalCode></st1:place><br>
> _______________________________________________<br>
> Leish-l mailing list<br>
> <a
href="http://us.mc1612.mail.yahoo.com/mc/compose?to=Leish-l@lineu.icb.usp.br"
ymailto="mailto:Leish-l@lineu.icb.usp.br">Leish-l@lineu.icb.usp.br</a><br>
> <a href="http://lineu.icb.usp.br/cgi-bin/mailman/listinfo/leish-l"
target="_blank">http://lineu.icb.usp.br/cgi-bin/mailman/listinfo/leish-l</a><br>
> <br>
> -- <br>
> This message has been scanned for viruses and<br>
> dangerous content by MailScanner, and is<br>
> believed to be clean.<br>
> <br>
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