<html><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; ">Dear KP,<div>You should talk (email) with Abhay Satoskar who is carrying out a trial in India and has talked with an official at WHO who is interested in a multi-center study which would be needed for the WHO to recommend the heat Rx. Abhay can give you details.</div><div>John</div><div><br></div><div><br><div><div>On Jun 6, 2011, at 12:02 PM, Chang, Kwang-Poo wrote:</div><br class="Apple-interchange-newline"><blockquote type="cite"><span class="Apple-style-span" style="border-collapse: separate; color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-border-horizontal-spacing: 0px; -webkit-border-vertical-spacing: 0px; -webkit-text-decorations-in-effect: none; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; font-size: medium; "><div lang="EN-US" link="blue" vlink="purple" style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; "><o:smarttagtype namespaceuri="urn:schemas-microsoft-com:office:smarttags" name="country-region"><o:smarttagtype namespaceuri="urn:schemas-microsoft-com:office:smarttags" name="place"><div class="Section1" style="page: Section1; "><div style="margin-top: 0in; margin-right: 0in; margin-bottom: 0.0001pt; margin-left: 0in; font-size: 12pt; font-family: 'Times New Roman'; "><font size="2" color="navy" face="Arial"><span style="font-size: 10pt; font-family: Arial; color: navy; ">Any chance to make it available for additional trials elsewhere ?<o:p></o:p></span></font></div><div style="margin-top: 0in; margin-right: 0in; margin-bottom: 0.0001pt; margin-left: 0in; font-size: 12pt; font-family: 'Times New Roman'; "><font size="2" color="navy" face="Arial"><span style="font-size: 10pt; font-family: Arial; color: navy; "><o:p> </o:p></span></font></div><div style="margin-top: 0in; margin-right: 0in; margin-bottom: 0.0001pt; margin-left: 0in; font-size: 12pt; font-family: 'Times New Roman'; "><font size="2" color="navy" face="Arial"><span style="font-size: 10pt; font-family: Arial; color: navy; ">I recall your statement in our conversation about the advantage of this instrument over the heating lamp. That is to maintain the specific elevated temperature uniformly throughout the skin lesion for a sustained period. The 50 C must be the effective temperature that has been experimentally determined. It seems to be a tolerable temperature to human skin ? Dr. Sharma may comment on this medically as a dermatologist ?<o:p></o:p></span></font></div><div style="margin-top: 0in; margin-right: 0in; margin-bottom: 0.0001pt; margin-left: 0in; font-size: 12pt; font-family: 'Times New Roman'; "><font size="2" color="navy" face="Arial"><span style="font-size: 10pt; font-family: Arial; color: navy; "><o:p> </o:p></span></font></div><div style="margin-top: 0in; margin-right: 0in; margin-bottom: 0.0001pt; margin-left: 0in; font-size: 12pt; font-family: 'Times New Roman'; "><font size="2" color="navy" face="Arial"><span style="font-size: 10pt; font-family: Arial; color: navy; ">KP<o:p></o:p></span></font></div><div style="margin-top: 0in; margin-right: 0in; margin-bottom: 0.0001pt; margin-left: 0in; font-size: 12pt; font-family: 'Times New Roman'; "><font size="2" color="navy" face="Arial"><span style="font-size: 10pt; font-family: Arial; color: navy; "><o:p> </o:p></span></font></div><div><div class="MsoNormal" align="center" style="margin-top: 0in; margin-right: 0in; margin-bottom: 0.0001pt; margin-left: 0in; font-size: 12pt; font-family: 'Times New Roman'; text-align: center; "><font size="3" face="Times New Roman"><span style="font-size: 12pt; "><hr size="2" width="100%" align="center" tabindex="-1"></span></font></div><div style="margin-top: 0in; margin-right: 0in; margin-bottom: 0.0001pt; margin-left: 0in; font-size: 12pt; font-family: 'Times New Roman'; "><b><font size="2" face="Tahoma"><span style="font-size: 10pt; font-family: Tahoma; font-weight: bold; ">From:</span></font></b><font size="2" face="Tahoma"><span style="font-size: 10pt; font-family: Tahoma; "><span class="Apple-converted-space"> </span>John David [<a href="mailto:jdavid@hsph.harvard.edu" style="color: blue; text-decoration: underline; ">mailto:jdavid@hsph.harvard.edu</a>]<span class="Apple-converted-space"> </span><br><b><span style="font-weight: bold; ">Sent:</span></b><span class="Apple-converted-space"> </span>Sunday, June 05, 2011 11:18 PM<br><b><span style="font-weight: bold; ">To:</span></b><span class="Apple-converted-space"> </span>Chang, Kwang-Poo<br><b><span style="font-weight: bold; ">Cc:</span></b><span class="Apple-converted-space"> </span>Sharmanl; Satoskar, Abhay; Raj; Petr Volf;<span class="Apple-converted-space"> </span><a href="mailto:leish-l@lineu.icb.usp.br" style="color: blue; text-decoration: underline; ">leish-l@lineu.icb.usp.br</a>;<span class="Apple-converted-space"> </span><a href="mailto:hgoto@usp.br" style="color: blue; text-decoration: underline; ">hgoto@usp.br</a>;<span class="Apple-converted-space"> </span><a href="mailto:elfadil_abass@yahoo.com" style="color: blue; text-decoration: underline; ">elfadil_abass@yahoo.com</a>;<span class="Apple-converted-space"> </span><a href="mailto:vishwamohan_katoch@yahoo.co.in" style="color: blue; text-decoration: underline; ">vishwamohan_katoch@yahoo.co.in</a><br><b><span style="font-weight: bold; ">Subject:</span></b><span class="Apple-converted-space"> </span>Re: [Leish-l] inquiry</span></font><o:p></o:p></div></div><div style="margin-top: 0in; margin-right: 0in; margin-bottom: 0.0001pt; margin-left: 0in; font-size: 12pt; font-family: 'Times New Roman'; "><font size="3" face="Times New Roman"><span style="font-size: 12pt; "><o:p> </o:p></span></font></div><div style="margin-top: 0in; margin-right: 0in; margin-bottom: 0.0001pt; margin-left: 0in; font-size: 12pt; font-family: 'Times New Roman'; "><font size="3" face="Times New Roman"><span style="font-size: 12pt; ">The Themomed instrument shown below can produce accurate 50 degrees C plus or minus 0.2 degrees temperature by radio wave.<o:p></o:p></span></font></div><div><div style="margin-top: 0in; margin-right: 0in; margin-bottom: 0.0001pt; margin-left: 0in; font-size: 12pt; font-family: 'Times New Roman'; "><font size="3" face="Times New Roman"><span style="font-size: 12pt; ">from Themorsurgery Technologies. Picture below.<o:p></o:p></span></font></div></div><div><div style="margin-top: 0in; margin-right: 0in; margin-bottom: 0.0001pt; margin-left: 0in; font-size: 12pt; font-family: 'Times New Roman'; "><font size="3" face="Times New Roman"><span style="font-size: 12pt; ">Two papers of a trial in<span class="Apple-converted-space"> </span><st1:country-region w:st="on">Brazil</st1:country-region><span class="Apple-converted-space"> </span>and one in<span class="Apple-converted-space"> </span><st1:country-region w:st="on"><st1:place w:st="on">Afghanistan</st1:place></st1:country-region><span class="Apple-converted-space"> </span>on CL below.<o:p></o:p></span></font></div></div></div></o:smarttagtype></o:smarttagtype></div></span></blockquote></div><br></div></body></html>