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<DIV><FONT size=2 face=Arial>G'Day Dr Hanafi,</FONT></DIV>
<DIV><FONT size=2 face=Arial>My enquiry was to know whether <EM>L. donovani</EM>
in India produces a cutaneous form of lesion or not (I am
not referring to PKDL form). There are many reports from SriLanka
about the cutaneous manifestations by <EM>L. donovani</EM>. The
PKDL although is a cutaneous response appears very late in
the infection process and this is ascribed to be a protective
response against the parasite. </FONT></DIV>
<DIV><FONT size=2 face=Arial></FONT> </DIV>
<DIV><FONT size=2 face=Arial>Prof Chang mentioned </FONT></DIV>
<DIV>"Analyses of several batches of basically clinical CL samples from Dr.
Sharma showed evidence of L infantum, but also L tropica as well as a mixture of
the two in one sample. This is the same picture we have noted for samples from
Hatay, Turkey." This is from Sutlej region." It means this cutaneous
complex requires some investigation. </DIV>
<DIV> </DIV>
<DIV>I raise species-specific exo-antigens from <EM>L. tropica</EM> and <EM>L
infantum</EM> and I am prepared to test the serum /plasma samples for presence
of antibodies. If Dr NL Sharma is prepared to send me specimens as well as
clinical plasma or serum samples I would be interested to investigate the
antibody response in these situations. </DIV>
<DIV> </DIV>
<DIV><FONT size=2 face=Arial>Dr Raj</FONT></DIV>
<DIV><FONT size=2 face=Arial>Cellabs</FONT></DIV>
<DIV><FONT size=2 face=Arial>----- Original Message ----- </FONT>
<DIV><FONT size=2 face=Arial>From: "Hanafi, Hanafi CTR EG NAMRU3 " <</FONT><A
href="mailto:hanafi.hanafi.ctr.eg@med.navy.mil"><FONT size=2
face=Arial>hanafi.hanafi.ctr.eg@med.navy.mil</FONT></A><FONT size=2
face=Arial>></FONT></DIV>
<DIV><FONT size=2 face=Arial>To: "Raj" <</FONT><A
href="mailto:raj@cellabs.com.au"><FONT size=2
face=Arial>raj@cellabs.com.au</FONT></A><FONT size=2 face=Arial>>;
<</FONT><A href="mailto:leish-l@lineu.icb.usp.br"><FONT size=2
face=Arial>leish-l@lineu.icb.usp.br</FONT></A><FONT size=2
face=Arial>></FONT></DIV>
<DIV><FONT size=2 face=Arial>Sent: Tuesday, May 31, 2011 6:19 PM</FONT></DIV>
<DIV><FONT size=2 face=Arial>Subject: RE: [Leish-l] Leish-l Digest, Vol 41,
Issue 9</FONT></DIV></DIV>
<DIV><FONT face=Arial><BR><FONT size=2></FONT></FONT></DIV><FONT size=2
face=Arial>> Dear Dr Raj:<BR>> <BR>> I think you mean PKDL (post kala
azar dermal leishmanisis) caused by L.<BR>> donovani and it usually seen as a
late complication of the disease. PKDL has<BR>> been reported in India, Kenya
and Sudan.<BR>> <BR>> Thank you <BR>> R/<BR>>
Hanafi<BR>> <BR>> Hanafi A. Hanafi, Ph. D.<BR>>
Medical Research Scientist<BR>> Vector Biology Research Program<BR>> U.S.
Naval Medical Research Unit No.3<BR>> Cairo, Egypt<BR>> Tel &
Fax: ++2-02-2342-3090<BR>> E-mail: </FONT><A
href="mailto:hanafi.hanafi.ctr.eg@med.navy.mil"><FONT size=2
face=Arial>hanafi.hanafi.ctr.eg@med.navy.mil</FONT></A><BR><FONT size=2
face=Arial>> </FONT><A
href="mailto:yahanafi@yahoo.com"><FONT size=2
face=Arial>yahanafi@yahoo.com</FONT></A><BR><FONT size=2 face=Arial>>
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