<font face="Tahoma" size="2"><span style="font-size: 10pt; font-family: Tahoma;"></span></font><font face="Arial" size="2"><span style="font-size: 10pt; font-family: Arial;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Dear colleagues,</span></font><p style="margin-left: 35.4pt;">
 </p>

<p style="margin-left: 35.4pt;"><font face="Arial" size="2"><span style="font-size: 10pt; font-family: Arial;">We have the pleasure to share with you that<b><span style="font-weight: bold;"> sanofi-Aventis</span></b> has announced offically WHO
with the reduction of a &quot;no-profit, no-loss&quot; price of GLUCANTIME
to&nbsp;<u> US</u></span></font><u><font face="Arial" size="2"><span style="font-size: 10pt; font-family: Arial;" lang="EN-GB">$ 1,20 per
vial + customs taxes + distribution cost</span></font></u><font face="Arial" size="2"><span style="font-size: 10pt; font-family: Arial;">&nbsp; to Public
Sector Agencies of all Developing Countries, for the treatment of</span></font><u>
</u><u><font face="Arial" size="2"><span style="font-size: 10pt; font-family: Arial;">leishmaniasis</span></font></u><font face="Arial" size="2"><span style="font-size: 10pt; font-family: Arial;">. This
important achievement will have enormous impact in many regions in the control
of this neglected tropical disease.</span></font></p>

<p style="margin-left: 35.4pt;"><font face="Arial" size="2"><span style="font-size: 10pt; font-family: Arial;">The reduction is effective from now. Interested can
enter in contact directly with sanofi-Aventis commercials in each country. If
you have any question, contact WHO, please.</span></font></p>

<p style="margin-left: 35.4pt;"><font face="Arial" size="2"><span style="font-size: 10pt; font-family: Arial;" lang="EN-GB">Please,
circulate this important information.</span></font><span lang="EN-GB"> </span></p>

<p style="margin-left: 35.4pt;"><font face="Arial" size="2"><span style="font-size: 10pt; font-family: Arial;" lang="EN-GB">Yours
sincerely,</span></font><span lang="EN-GB"> </span></p>

<p style="margin-left: 35.4pt;"><font face="Courier New" size="2"><span style="font-size: 10pt;" lang="EN-US">Dr
Jorge Alvar</span></font><span lang="EN-US"> </span></p>

<p style="margin-left: 35.4pt;"><font face="Courier New" size="2"><span style="font-size: 10pt;" lang="EN-US">Medical
Officer (Leishmaniasis Control)</span></font> <br>
<b><font face="Courier New" size="2"><span style="font-size: 10pt; font-weight: bold;" lang="EN-US">Control of
Neglected Tropical Diseases</span></font></b><span lang="EN-US"> </span><br>
<font face="Courier New" size="2"><span style="font-size: 10pt;" lang="EN-US">Innovative and Intensified
Disease Management</span></font> <br>
<font face="Courier New" size="2"><span style="font-size: 10pt;" lang="EN-US">Communicable Diseases
Cluster</span></font> <br>
<b><font face="Courier New" size="2"><span style="font-size: 10pt; font-weight: bold;" lang="EN-US">World
Health Organization</span></font></b> <br>
<font face="Courier New" size="2"><span style="font-size: 10pt;" lang="EN-US">20, Avenue Appia;
CH-1211&nbsp; Geneva 27</span></font> <br>
<font face="Courier New" size="2"><span style="font-size: 10pt;" lang="EN-US">Tel.&nbsp;&nbsp;&nbsp; <span onmouseup="SetCallButtonPressed(this, 0,1)" onmousedown="SetCallButtonPressed(this, 1,1)" onmouseover="SetCallButton(this, 1,1);skype_active=CheckCallButton(this);" onmouseout="SetCallButton(this, 0,1);HideSkypeMenu();" class="skype_tb_injection" id="__skype_highlight_id">
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<font face="Courier New" size="2"><span style="font-size: 10pt;" lang="EN-US">Fax&nbsp;&nbsp;&nbsp;&nbsp;
+41 22 791 4877</span></font> <br>
<font face="Courier New" size="2"><span style="font-size: 10pt;" lang="EN-US">e-mail: <a href="mailto:alvarj@who.int" target="_blank" onclick="return top.js.OpenExtLink(window,event,this)">alvarj@who.int</a></span></font>
</p>