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Dear Colleague,<BR>
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I am searching for motivated individuals to fill 2 post-doctoral positions that I have the resources to fund. The positions are at New York University Medical School in the Department of Medical and Molecular Parasitology, located in Manhattan. Their research will focus on human Trypanosome Lytic Factors (TLFs). These factors are 2 novel forms of high-density lipoprotein particles that kill T. b. brucei, the bovine infective subspecies of African trypanosomes. The human infective subspecies, T. b. rhodesiense and T. b. gambiense are refractory to these lytic factors.<BR>
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For relevant references see :<BR>
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S. Tomlinson and J. Raper (1998) Natural human immunity to trypanosomes. Parasitol. Today . 14, 354-359. <BR>
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J. Raper, R. Fung, G. Ghiso, V,. Nussenzweig and S. Tomlinson. (1999) The characterisation of a novel trypanosome lytic factor in human serum. Infection and Immunity, 67,1910-6. <BR>
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</I> The goal of one position will be to clone a novel Trypanosome receptor that mediates killing by TLFs. Desirable skills include library construction, and library screening by low-stringency methods or antibodies.<BR>
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The other position will focus on the role of TLFs in the development of atherosclerosis. Familiarity with lipoproteins and their metabolism is a big plus.<BR>
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Interested candidates should send their CV and the names of 3 references to Jayne Raper at:<BR>
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jr57@is2.nyu.edu<BR>
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Please feel free to post or forward this message to any candidates that you think might be interested. <BR>
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Thanks for your time.<BR>
Sincerely,<BR>
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Jayne Raper, Ph.D.<BR>
Department of Medical and Molecular Parasitology <BR>
New York University School of Medicine <BR>
341 East 25th St.<BR>
New York, NY 10010<BR>
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