[Leish-l] cutaneous form of leish in Indian region

[Chang, Kwang-Poo]

Great if Dr. Sharma would be able to send serum samples to you for
evaluating your species-specific exo-antigens.

 

KP

 

________________________________

From: Raj [mailto:raj at cellabs.com.au] 
Sent: Tuesday, May 31, 2011 9:18 PM
To: Hanafi, Hanafi CTR EG NAMRU3 ; Chang, Kwang-Poo;
nandlals at hotmail.com; leish-l at lineu.icb.usp.br
Subject: cutaneous form of leish in Indian region

 

G'Day Dr Hanafi,

My enquiry was to know whether L. donovani in India produces a cutaneous
form of lesion or not (I am not referring to PKDL form). There are many
reports from SriLanka about the cutaneous manifestations by L. donovani.
The PKDL although is a  cutaneous response appears very late in the
infection process and this is ascribed to be a protective response
against the parasite. 

 

Prof Chang mentioned 

"Analyses of several batches of basically clinical CL samples from Dr.
Sharma showed evidence of L infantum, but also L tropica as well as a
mixture of the two in one sample. This is the same picture we have noted
for samples from Hatay, Turkey." This is from Sutlej region." It means
this cutaneous  complex requires some investigation. 

 

I raise species-specific exo-antigens from L. tropica and L infantum and
I am prepared to test the serum /plasma samples for presence of
antibodies.  If Dr NL Sharma is prepared to send me specimens as well as
clinical plasma or serum samples I would be interested to investigate
the antibody response in these situations. 

 

Dr Raj

Cellabs

----- Original Message ----- 

From: "Hanafi, Hanafi CTR EG NAMRU3 "
<hanafi.hanafi.ctr.eg at med.navy.mil>

To: "Raj" <raj at cellabs.com.au>; <leish-l at lineu.icb.usp.br>

Sent: Tuesday, May 31, 2011 6:19 PM

Subject: RE: [Leish-l] Leish-l Digest, Vol 41, Issue 9

 

> Dear Dr Raj:
> 
> I think you mean PKDL (post kala azar dermal leishmanisis) caused by
L.
> donovani and it usually seen as a late complication of the disease.
PKDL has
> been reported in India, Kenya and Sudan.
> 
> Thank you 
> R/
> Hanafi
>   
> Hanafi  A.  Hanafi, Ph. D.
> Medical Research Scientist
> Vector Biology Research Program
> U.S. Naval Medical Research Unit No.3
> Cairo, Egypt
> Tel & Fax:  ++2-02-2342-3090
> E-mail: hanafi.hanafi.ctr.eg at med.navy.mil
>        yahanafi at yahoo.com
> 






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