[Leish-l] Leishmania genomes and Mapviewer in NCBI news
fred opperdoes
fred.opperdoes at uclouvain.be
Tue Apr 15 11:10:16 BRT 2008
Leishmania Genomes
Leishmaniasis, a parasitic disease caused by various species of the
protozoan genus Leishmania, is an important health problem in much of
the tropical parts of the world, causing disfiguring cutaneous lesions
and more serious complications. NCBI (http://www.ncbi.nlm.nih.gov/)
now has the genomes of two of the human pathogenic species of
Leishmania (L. braziliensis and L. infantum). Both genomes will be
important in further understanding the biology of these parasites and
will help in developing new strategies to combat this disease. The
braziliensis and infantum genomes are comprised of completely
annotated chromosome records with associated genes and model
transcripts. The braziliensis genome was submitted by the Wellcome
Trust Sanger Institute and has 31.4 Megabases comprising the 35
chromosomes with 8,129 annotated genes and gene models. The infantum
genome submitted by a consortium that included The Wellcome Trust
Sanger Institute, Imperial College, and University of Glasgow has 32.1
Megabases comprising the 36 chromosomes with 8,186 annotated genes and
gene models. For the Leishmania genomes, the contig, gene, and
transcript maps are available within Map Viewer (http://www.ncbi.nlm.nih.gov/projects/mapview/map_search.cgi?taxid=5664
).
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