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Sat Feb 18 11:22:33 BRST 2006
Tomas Hospital and Gorgas Memorial Laboratory to study the etiology,
epidemiology and clinical characteristics of mucocutaneous leishmaniasis
. Seventeen were males and 16 females, 14 to 80 years old from the
endemic rural areas of the provinces of Panama, Colón, Coclé, Darién
, Veraguas, Bocas del Toro and San Blas. In 8 patients the respiratory
mucosa involvement occurred at the time of the primary infection and 25
had the involvement after an incubation period of 2 to 30 years. Twenty
one of these 25 patients had a clear history of cutaneous leishmaniasis
and the characteristic depressed and hyperpigmented scar of a previous
leishmanial infection. The Montenegro skin test was positive in all the
patients, serology in 84%, direct smear in 47%, histopathology in 37%
and culture in 26%. The strains were characterized as L. braziliensis
panamensis by electrophoresis of isoenzymes. Possible risk factors in
development of MCL were found to be female sex and the lack of past
treatment of CL. The mucosal involvement was mild in the majority of the
patients, the infection was localized in the nasal mucosal (nasal
septum and inferior turbinate) in 91% of the patients, and the most
common symptoms were epistaxis, nasal obstruction and rhinorrhea.
PMID: 3347765
TITLE: [Cutaneous leishmaniasis caused by Leishmania mexicana amazonensis in
Panama]
AUTHORS: J Petersen, C M Johnson, A M de Vázquez, R Sáenz
REFERENCE: Rev Med Panama 1988 Jan 13(1):158-64
PMID: 3423320
TITLE: [Cutaneous leishmaniasis caused by Leishmania mexicana amazonensis in
Panama]
AUTHORS: J Petersen, C M Johnson, A M de Vásquez, R Sáenz
REFERENCE: Rev Med Panama 1987 Sep 12(3):158-64
PMID: 2827242
TITLE: [Evaluation of the effectiveness and toxicity of pentostam and glucantime
in the treatment of cutaneous leishmaniasis]
AUTHORS: R E Sáenz, H M Paz, C M Johnson, E Narvaez, A M de Vásquez
REFERENCE: Rev Med Panama 1987 Sep 12(3):148-57
PMID: 2892231
TITLE: [Outline of principal diseases transmitted by insects in Panama]
AUTHORS: B Chaniotis, E Méndez
REFERENCE: Rev Med Panama 1987 Sep 12(3):205-16
PMID: 6494504
TITLE: [Cutaneous leishmaniasis in Panama. A brief review]
AUTHORS: H A Christensen, C M Johnson, A M de Vásquez
REFERENCE: Rev Med Panama 1984 Sep 9(3):182-7
REQUEST: [ leishmania ]
(21 articles match this request. 16 articles matching other requests removed)
PMID: 15301978
TITLE: Detection of high rates of in-village transmission of Leishmania donovani
in eastern Sudan.
AUTHORS: M M Hassan, F M A Elraba'a, R D Ward, R D C Maingon, D A Elnaiem
AFFILIATION: Department of Zoology, Faculty of Science, University of Khartoum,
P. O. Box 321, Khartoum, Sudan.
REFERENCE: Acta Trop 2004 Sep 92(1):77-82
PMID: 15147677
TITLE: Genetics and visceral leishmaniasis in the Sudan: seeking a link.
AUTHORS: Jenefer M Blackwell, Hiba S Mohamed, Muntaser E Ibrahim
AFFILIATION: Cambridge Institute for Medical Research, Wellcome Trust/MRC
Building, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, U.K.
jennie.blackwell at cimr.cam.ac.kr
REFERENCE: Trends Parasitol 2004 Jun 20(6):268-74
PMID: 15305702
TITLE: [Coxiella burnetii: which reality?]
AUTHORS: F Capuano, A Parisi, M A Cafiero, L Pitaro, D Fenizia
AFFILIATION: Istituto Zooprofilattico Sperimentale del Mezzogiomo, Portici.
REFERENCE: Parassitologia 2004 Jun 46(1-2):131-4
After the Second World War, in Italy Q Fever or Coxiellosis has been
shown a significant relevance, a recrudescence with an epidemic state
for over ten years. Later, the infectious disease occurred as endemic
since the 80s, the outbreaks were just isolated. Workflows analysis of
some authors has demonstrated the spread out of the infection throughout
Italian herds with a prevalence ranging from 1.2 per cent to 10 per
cent. Our survey carried out throughout Campania area in cattle has
shown a real positivity over 14 per cent performing the IFAT for the
detection of IgG antibodies for Coxiella burnetii. Therefore, it has
been so important to stress the influence of cattle farming management
in stables as a real risk of Coxiellosis. For example, the Relative Risk
(RR) has been registrated about 6.84 (2.18<RR<21.4) in
comparison with some herds permanently housed than those kept unhoused
and about 8.4 (1.8<RR<38.6) in housed herds and those
permanently kept at pasture. Therefore, we have detected a
seroprevalence of Q Fever about 11.8 per cent within sheep and about 6.3
per cent within goats. The investigations have focused buffaloes too,
tested by several authors, especially from India, but in Italy, only
Galiero has recorded significant results: the overall seroprevalence (1.
2 per cent) was observed within 1012 buffaloes. Other studies have
demonstrated that dogs may transmit Q Fever to humans by infected birth
fluids and membranes and by urine. Because of this observation,
addressed some of our search projects to assess possible relation among
other pathogens, such as Leishmania infantum, Rickettsia conori and
Ehrlichia canis. The results have confirmed the presence of C. burnetii
(seroprevalence about 7 per cent) within tested dogs in southern Italy
. There was no direct estimated relationship between C. burnetii and E.
canis and R. conori, instead of significant relation has been shown for
L. infantum. The investigation focused on the direct interaction between
seropositivity and the age of ruminants. For example, the highest
prevalence has been observed in cows and sheep ranging from 3-5 years in
which the infection risk was higher than in younger herds. In
accordance with the workflows serological analysis, C. burnetii is
widespread in Italy among housed ruminants. PCR assay was, therefore
performed to test cows with clinical signs of abortion and neonatal
mortality. All the survey involved 305 animals (267 foeti and 38
stillborn) with 77 positive herds showing DNA of C. burnetii. To detect
C. burnetii pathogen in milk samples, two methods have been combined:
the immunomagnetic separation (IMS) and PCR assay, obtaining an
increasing of sensitivity (10(-17)) more than only PCR technique (10(-8
)). The overall analysis of serological and biomolecular results has
demonstrated that C. burnetii is really widespread and may have
detrimental effects on farm management system.
PMID: 15305707
TITLE: [Histology in diagnosis of parasitic diseases]
AUTHORS: S Papparella
AFFILIATION: Dipartimento di Patologia e Sanità animale-settore di Anatomia
patologica Facoltà di Medicina Veterinaria, Università degli Studi di Napoli
Federico II.
REFERENCE: Parassitologia 2004 Jun 46(1-2):157-8
Many pathogenic organisms cause inflammatory lesions and microscopic
findings are a useful diagnostic tool for the aetiological diagnosis.
However, the histological lesions are limited in respect to many
biological agents that can damage the tissues. The histologic hallmark
of parasitic diseases is mostly granulomatous inflammation. It is
characterized by a focal infiltration of macrophages and epithelioid
cells. Many giant cells, lymphocytes, plasma cells, fibroblasts and
granulocytes can be found. Agents inducing granulomas include helminths
and parasites that replicate intracellularly. Some special stains are
utilized in histopathology, for example Giemsa's stain is useful to
identify Leishmania. Using specific antibodies, immunohistochemical
methods provide an aetiological diagnosis. Sometimes, tissue damage can
be immuno-mediated depending on deposit of circulating immunocomplexes
or T-lymphocytes involvement rather than by direct parasitic injury.
Generally, the lesions which can be observed are respectively vasculitis
and inflammatory reactions predominantly composed of mononuclear cells
, as observed in many viral or bacterial diseases. In these cases,
aetiological diagnosis is improved by in situ-PCR. For microscopic
identification of parasites in tissues it is also important to be
familiar with the kind of parasites most likely to be found in the
examined tissue and in that particular host. Localization of parasites
can induce hyperplastic-neoplastic lesions. Many parasites have been
associated with the occurrence of specific types of neoplasms, but the
mechanisms involved are still not well defined. Chronic inflammation and
/or immune suppression seem to induce neoplastic proliferation.
PMID: 15307425
TITLE: Clinical status and parasitic infection in a Wichà Aboriginal community
in Salta, Argentina.
AUTHORS: N J Taranto, S P Cajal, M C De Marzi, M M Fernández, F M Frank, A M
Brú, M C Minvielle, J A Basualdo, E L Malchiodi
AFFILIATION: Instituto de Investigaciones en Enfermedades Tropicales and
Cátedra de MicrobiologÃa y ParasitologÃa, Sede Regional Orán, Universidad
Nacional de Salta, Salta, Argentina.
REFERENCE: Trans R Soc Trop Med Hyg 2003 Sep-Oct 97(5):554-8
In a study, carried out in 2000, of the clinical and parasitological
status of a Wichi Aboriginal community living in the suburbs of Tartagal
, northern Salta, Argentina, 154 individuals were screened for parasitic
infections. Ninety-five faecal samples were also obtained from the same
population. Ninety-three percent of the subjects were positive for 1 or
more of the parasites investigated by direct test and 70.5% of them had
parasitic superinfection. The most frequent helminths were
Strongyloides stercoralis (50.5%) and hookworm (47.4%). We found low
reinfection rates and a long reinfection period after treatment and
provision of safe water and sanitation. Serum reactivity of these
patients was analysed by enzyme-linked immunosorbent assay and indirect
immunofluorescent assay and 22.1% of them had anti-Toxocara antibodies,
16.2% were positive for a complex antigen of Leishmania braziliensis, 29
.9% were positive for a complex Trypanosoma cruzi antigen, and 17.5%
were positive for a specific Trypanosoma cruzi antigen, Ag 163B6/
cruzipain.
REQUEST: [ sand fly ]
(0 articles match this request)
REQUEST: [ sandfly ]
(1 article matches this request. 1 article matching other requests removed)
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