Anti-leishmanial drug from Galipea logiflora

[desjeuxp at who.ch]

Dear Jacques


Yes, the plant exists in Bolivia and Perou and is used by Indians Chimanes
living in tropical forest of "Alto Beni" in Bolivia, to cure cutaneous
leishmaniasis lesions. The plant has been comprehensively studied by a
Bolivian/French team at IBBA, La Paz, Bolivia. In vitro and in vivo assays were
carried out. The chemical structure is well known. For any complementary
information please contact the "Institut pour la Recherche et Développement"
(IRD), ex ORSTOM, 213 Rue Lafayette, 75480 Paris Cedex 10, France. Fax: (0033) 1
48 03 78 06.

Best personal regards.


P. Desjeux, WHO, CSR/EDC  

____________________Reply Separator____________________
Subject:    Anti-leishmanial drug from Galipea logiflora
Author: Jacques Mauel <Jacques.Mauel at ib.unil.ch>
Date:       6-Jan-2000 08:34

Dear colleagues,

This is a request for information regarding a potential 
anti-leishmanial agent isolated from the plant Galipea longiflora 
(Eventa) said to be relatively common in the Peruvian forest. 
Apparently, a new drug called "chimanine", obtained from this plant, 
has been patented by the "Coopératrion française"

Has anyone any further information regarding this product ? Does it 
exist ? Is it actually being tested ? Are the results available ?

Thanks for your help.
Jacques Mauël
Jacques Mauel
Institute of Biochemistry
Ch. des Boveresses 155
CH-1066 EPALINGES
Switzerland
Tel ++41 21 692 57 04
Fax ++41 21 692 57 05